Pharmacology (cardiovascular disease) PhD Projects, Programmes & Scholarships

We have 17 Pharmacology (cardiovascular disease) PhD Projects, Programmes & Scholarships

Network-based predictive modelling of cardiovascular disease risk

University of Liverpool Institute of Systems, Molecular and Integrative Biology

The risk of cardiovascular disease (CVD) is orchestrated by multiple factors. QRISK models (currently QRISK3) have been used in the UK to estimate CVD risk within the next 10 years for individuals without CVD. Read more

Supervisor: Dr T You

Year round applications PhD Research Project Self-Funded PhD Students Only

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Application and development of bioinformatics and network theory methods in cardiovascular disease research and pharmacovigilance

Semmelweis University Budapest Department of Pharmacology and Pharmacotherapy

To be able to discover novel drug targets we aim to develop software based on network theoretic approaches that are capable to identify mediators and pathways involved in the pathomechanism of various cardiovascular diseases by the analysis of datasets assessed with high throughput molecular biological techniques (e.g. Read more

Supervisor: Dr B Ágg

Year round applications PhD Research Project Funded PhD Project (European/UK Students Only)

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Examining the mechanisms that cause cardiovascular disease by studying the heart or adipose tissue

University of Reading Department of Biomedical Sciences

Heart failure has a serious impact on our society and once diagnosed has a poor survival rate. In the United Kingdom, there are about 1.5 million people living with the after-effects of a heart attack. Read more

Supervisor: Dr S Boateng

Year round applications PhD Research Project Self-Funded PhD Students Only

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NIHR Leeds BRC: Force sensing mechanisms of haemostasis in heart failure and diabetes

University of Leeds Faculty of Medicine and Health

Since the original identification of the role of PIEZO1 in vascular integrity and endothelial cell biology by our group in Leeds in 2014, there have been many publications on the role of PIEZO1 in endothelial function and its role in processes such as atherosclerosis, hypertension, cell-cell junctions, vascular permeability and leukocyte diapedesis. Read more

Supervisors: Dr R Ariens, Prof D J Beech, Dr E Levelt

26 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Investigation of short-term effects of colchicine on blood proteins using proteomics

University of Dundee School of Medicine

The anti-inflammatory medication colchicine has been shown to significantly improve cardiovascular outcomes post heart attack and in chronic heart disease patient groups, suggesting it may be a suitable candidate for repurposing in cardiovascular diseases. Read more

Supervisors: Prof G Rena, Dr I Mordi, Prof C Lang

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Using CRISPR in iPS cells to modify platelet function

University of Reading Department of Biomedical Sciences

Project Overview. Platelets are the small cells in the blood whose job it is to prevent bleeding. Under normal conditions, when they encounter a damaged blood vessel they become activated and form a thrombus. Read more

Supervisor: Dr C.E. Hughes

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding the molecular mechanisms of thrombosis and haemostasis

University of Reading Department of Biomedical Sciences

Project Overview: . The risk of heart attack or stroke is elevated in obesity and in people with metabolic disorders such as diabetes. Read more

Supervisors: Dr C.E. Hughes, Prof J M Gibbins

Year round applications PhD Research Project Self-Funded PhD Students Only

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The role of extracellular vesicles in signalling between cardiovascular cell types in metabolic diseases and in cardioprotective therapies

Semmelweis University Budapest Department of Pharmacology and Pharmacotherapy

We are to understand how EVs induce and affect cardiovascular diseases. To this end, we investigate its changes in disease models of the cardiovascular system and in its comorbidities, e.g., metabolic diseases. Read more

Supervisor: Dr Z Giricz

Year round applications PhD Research Project Funded PhD Project (European/UK Students Only)

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Interaction between innate immune activation and endothelial cells, linked to adverse cardiovascular events

University of Liverpool Institute of Systems, Molecular and Integrative Biology

The complement system is a key component of the immune response. Maintaining a balance between activation and inhibition of the complement system is key to preserving tissue homeostasis and enabling immune surveillance. Read more

Supervisors: Dr N Liptrott, Dr R Rainbow, Prof C Dart

Year round applications PhD Research Project Self-Funded PhD Students Only

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Identification of novel inflammatory mechanisms as potential therapeutic targets in cardiovascular and metabolic diseases

Semmelweis University Budapest Department of Pharmacology and Pharmacotherapy

The prognosis of chronic heart failure resulting from a heart attack is very poor, even with modern therapeutic devices and drugs, about half of the patients die within 5 years of diagnosis. Read more

Supervisor: Dr Z Varga

Year round applications PhD Research Project Funded PhD Project (European/UK Students Only)

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Therapeutic resolution of pulmonary arterial hypertension (PAH) by natural products

University of Bradford Faculty of Life Sciences

Research Group: Pharmacology and Experimental Therapeutics

Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more

Supervisors: Dr T Nasim, Prof C Wright

Year round applications PhD Research Project Self-Funded PhD Students Only

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Re-purposing established drugs for the resolution of pulmonary arterial hypertension (PAH)

University of Bradford Faculty of Life Sciences

Research Group: Pharmacology and Experimental Therapeutics

Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more

Supervisors: Dr T Nasim, Dr K Assi

Year round applications PhD Research Project Self-Funded PhD Students Only

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Neurovascular coupling in cerebral hypoperfusion

The University of Manchester Faculty of Biology, Medicine and Health

There are almost a million people living with dementia in the UK. Most of these cases comprise Alzheimer’s Disease (AD), vascular dementia (VaD) or, as is increasingly recognised, a mixed picture phenotype with evidence of the two conditions co-existent in the same patient. Read more

Supervisors: Dr H Pritchard, Dr A Greenstein, Dr I Schiessl, Prof S Allan

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Gaining mechanistic insights into Atrial Fibrillation: Bench to bedside approaches

University of Liverpool Department of Pharmacology and Therapeutics

Atrial fibrillation (AF) is a common arrhythmia with symptoms like irregular heart rate, palpitations, shortness of breath, tiredness, and dizziness. Read more

Supervisor: Dr RB Burton

1 July 2024 PhD Research Project Self-Funded PhD Students Only

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Investigation of myocardial ischemic adaptation in the presence of comorbidity factors on in vitro cell culture models

Semmelweis University Budapest Department of Pharmacology and Pharmacotherapy

Metabolic derangements, such as obesity or diabetes, are major risk factors of cardiovascular diseases. Read more

Supervisor: Dr A Görbe

Year round applications PhD Research Project Funded PhD Project (European/UK Students Only)

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We have 17 Pharmacology (cardiovascular disease) PhD Projects, Programmes & Scholarships

Pharmacology (cardiovascular disease) PhD Projects, Programmes & Scholarships

We have 17 Pharmacology (cardiovascular disease) PhD Projects, Programmes & Scholarships

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