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Pharmacology / Toxicology (cell culture) PhD Projects, Programs & Scholarships

We have 43 Pharmacology / Toxicology (cell culture) PhD Projects, Programs & Scholarships

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  Fully Funded Public Health England PhD Scholarship: Use of advanced multi-cellular models of the human respiratory system to investigate the mechanistic effects of particulate and gaseous air pollutants
  Dr M Clift
Application Deadline: 31 January 2020

Funding Type

PhD Type

This scholarship is funded by Public Health England (PHE). Start date. April 2020. Subject areas. In Vitro Systems; In Vivo Models; Cell Biology; Cell Culture; Toxicology; Air Pollution; Particulate; NO2.
  Understanding differential responses to retinoid treatments in human health and disease: a precision medicine approach
  Prof R Watson, Dr A Langton
Applications accepted all year round

Funding Type

PhD Type

Retinoids, such as all-trans retinoic acid (t-RA), are endogenous signalling molecules derived from vitamin A that influence a variety of cellular processes through mediation of transcription events in the cell nucleus.
  Cutting off the fuel supply to calcium pumps in pancreatic cancer: a novel therapeutic strategy
  Dr J Bruce, Prof K Williams, Dr A P Gilmore
Applications accepted all year round

Funding Type

PhD Type

Background and Rationale. Pancreatic ductal adenocarcinoma (PDAC) has the poorest survival and limited treatment options. Therefore, the search for novel therapeutic targets and drugs designed to selectively kill PDAC cells must remain a central research strategy.
  Molecular Pathology of Glaucoma
  Prof C Willoughby
Applications accepted all year round

Funding Type

PhD Type

Primary open-angle glaucoma (POAG) is a leading cause of blindness worldwide affecting over 64 million people. Glaucoma is a complex multifactorial ocular disease with significant health and socio-economic impact.
  Mechanisms of Cancer Stem Cell Survival, Metastasis Formation and Immune Evasion in Cancer
  Dr D Widera
Applications accepted all year round

Funding Type

PhD Type

Recent research suggests that cancer cells within a tumour represent a highly heterogeneous cell population. In particular many tumours contain small percentage of cells that share several characteristics with stem cells.
  In vitro assessment of drug sequestration into lysosomes and in silico prediction of implications for drug disposition and therapeutic efficacy
  Dr A Galetin, Dr D Hallifax
Applications accepted all year round

Funding Type

PhD Type

Intracellular concentration of a drug is an important determinant of its efficacy, toxicity, and potential drug-drug interactions [1].
  Precision Medicine DTP - An integrated computational-experimental approach to identify and optimise combination drug therapy for non-alcoholic fatty liver disease (NAFLD)
  Research Group: Centre for Inflammation Research
  Prof J Fallowfield, Dr F Menolascina, Prof J Plevris
Application Deadline: 8 April 2020

Funding Type

PhD Type

Background. Non-alcoholic fatty liver disease (NAFLD) is the commonest cause of chronic liver disease (CLD), affecting 1 in 4 people worldwide.
  Control of Parathyroid Hormone Secretion
  Dr D Ward, Dr J Bruce
Applications accepted all year round

Funding Type

PhD Type

The regulation of parathyroid hormone (PTH) secretion is of fundamental importance for calcium homeostasis and in mineral conditions affecting bone and the kidneys.
  Development and application of a multi-component 3-D in vitro model for predictive pharmacokinetics of environmental pharmaceuticals in fish
  Prof C Hogstrand
Application Deadline: 24 January 2020

Funding Type

PhD Type

Many medicinal drugs end up in the aquatic environment through patient use and the pharmaceutical industry is required to assess their risk to non-target organisms.
  Carbon Nanotubes Mediated Drug Delivery in 3D cancer models
  Dr H Ali-Boucetta
Applications accepted all year round

Funding Type

PhD Type

Current treatment with anticancer drugs suffers from the drawbacks of systemic toxicity, drug resistance and limited cellular entry.
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