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We have 18 Pharmacology (cell signalling) PhD Projects, Programmes & Scholarships

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Pharmacology (cell signalling) PhD Projects, Programmes & Scholarships

We have 18 Pharmacology (cell signalling) PhD Projects, Programmes & Scholarships

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Biological role of neuropeptides and their receptors

University of Reading School of Pharmacy
Cell signalling is critical to the co-ordination and functioning of all cells. Cell signalling allows cells to co-ordinate activities within the intracellular environment as well as ensuring cells know how to correctly respond to other cells and to an ever-changing extracellular environment as well. Read more
 Supervisor: Dr L Lander
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the role of P2X7 receptor intracellular domains in cell signalling

Cardiff University Cardiff School of Biosciences
Project description. P2X7 receptors are ion channels that are found on the surface of immune cells, where they respond to the binding of extracellular ATP, a damage signal released by dying cells in infection and injury. Read more
 Supervisors: Dr M Young, Dr J Parker
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the roles that G protein coupled receptors play in hypertension

University of Leicester Molecular and Cell Biology
G protein-coupled receptors (GPCRs) constitute a very large family of heptahelical, integral membrane proteins that mediate a wide variety of physiological processes ranging from the transmission of light and odorant signals to the mediation of neurotransmission and hormonal actions. Read more
 Supervisor: Dr J Willets
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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School of Life Sciences Black Scholars Programme

University of Dundee
The School of Life Sciences and the University of Dundee are committed to addressing under-representation in postgraduate research and we are pleased to offer our first Masters by Research Scholarships for UK students from Black or Black-Mixed Backgrounds. Read more
 Funded PhD Programme (Students Worldwide)  PhD Opportunities
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Self funded MSc by Research or PhD in Biology: Ion channel signalling in cancer cells

University of York Department of Biology
Lead supervisor: Dr W Brackenbury. The student will be registered with the Department of Biology. Our cells constantly sense and transport ions present in their environment. Read more
 Supervisor: Dr W Brackenbury
 30 June 2024  PhD Research Project  Self-Funded PhD Students Only
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Gaining mechanistic insights into Atrial Fibrillation: Bench to bedside approaches

University of Liverpool Department of Pharmacology and Therapeutics
Atrial fibrillation (AF) is a common arrhythmia with symptoms like irregular heart rate, palpitations, shortness of breath, tiredness, and dizziness. Read more
 Supervisor: Dr RB Burton
 1 July 2024  PhD Research Project  Self-Funded PhD Students Only
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The role of extracellular vesicles in signalling between cardiovascular cell types in metabolic diseases and in cardioprotective therapies

Semmelweis University Budapest Department of Pharmacology and Pharmacotherapy
We are to understand how EVs induce and affect cardiovascular diseases. To this end, we investigate its changes in disease models of the cardiovascular system and in its comorbidities, e.g., metabolic diseases. Read more
 Supervisor: Dr Z Giricz
 Year round applications  PhD Research Project  Funded PhD Project (European/UK Students Only)
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Targeting the MAPK scaffold protein KSR1 for the treatment of prostate cancer

University of Bradford Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Prostate cancer is one of the leading causes of male cancer deaths. It arises when individual cells escape their normal growth control mechanisms and proliferate in an uncontrolled fashion. Read more
 Supervisors: Dr J Muller, Prof R Falconer
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Inducing ferroptotic death to kill cancer cells

The University of Manchester Faculty of Biology, Medicine and Health
Ferroptosis is an iron-dependent form of regulated necrotic cell death triggered by oxidative degradation of lipids in membrane bilayers and subsequent irreparable damages to the plasma membrane (1). Read more
 Supervisors: Dr C Tournier, Dr K Finegan
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cancer Neuroscience: Investigating the impact of non-CNS tumours on neuronal plasticity in the brain

University of Nottingham School of Life Sciences
Cancer is one of the leading causes of death worldwide, resulting in approximately 18 million new cases and 10 million deaths each year. Read more
 Supervisor: Dr G Sheridan
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigation of the critical roles of platelets at the interface between thrombosis and inflammation in order to develop improved therapeutic strategies for the treatment and/or prevention of cardiovascular/inflammatory diseases

University of Reading School of Pharmacy
Platelets (small circulating blood cells) are involved in blood clotting to prevent excessive bleeding, however, their inappropriate activation under pathological conditions leads to thrombosis resulting in major cardiovascular diseases such as heart attack and stroke. Read more
 Supervisor: Prof SV Vaiyapuri
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Using chemical-genetics to inhibit and characterise “undruggable” enzymes

University of Dundee School of Medicine
The ability to inhibit kinases with small molecule drugs has transformed our understanding of signalling networks. It has allowed us to define the substrates and processes that each kinase controls, and to map how these enzymes cooperate within signalling pathways. Read more
 Supervisors: Dr A Saurin, Dr T Ly
 30 June 2024  PhD Research Project  Self-Funded PhD Students Only
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Investigating the neuro-stromal-immune interactions in inflammageing and osteoarthritis.

University of Greenwich School of Pharmacy (Medway Campus)
Ageing is associated with a higher risk of developing multiple chronic conditions (multimorbidity) including osteoarthritis. Age-associated chronic low-grade inflammation (inflammageing) is a hallmark of osteoarthritis. Read more
 Supervisor: Dr S Ashraf
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Analysis of the role of liver sinusoidal endothelial cells in methotrexate-induced liver toxicity

University of Liverpool Department of Pharmacology and Therapeutics
Liver sinusoidal endothelial cells (LSECs) comprise approximately 50% of the non-parenchymal hepatic cells. They play a vital role in hepatic microcirculation and provide a physiological barrier to the movement of xenobiotics from the bloodstream to hepatic tissue. Read more
 Supervisors: Dr M Cross, Prof C Goldring
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the links between β-amyloid, osteoporosis and frailty in Alzheimer’s disease

Queen Mary University of London Institute of Dentistry
Background. Individuals with Alzheimer’s disease are more likely to suffer from osteoporosis (the loss of bone mass and strength) than age-matched individuals1, significantly contributing to the frailty associated with dementia. Read more
 Supervisors: Dr S McArthur, Dr SCF Rawlinson
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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