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We have 19 Pharmacology (computational) PhD Projects, Programmes & Scholarships

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Pharmacology (computational) PhD Projects, Programmes & Scholarships

We have 19 Pharmacology (computational) PhD Projects, Programmes & Scholarships

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Structure-based design of allosteric modulators for G protein-coupled receptors using molecular modelling and pharmacology experiments

Queen’s University Belfast School of Pharmacy
Almost all physiological processes are regulated through the activation of G protein-coupled receptors (GPCRs). It has become widely accepted that most GPCRs possess binding sites spatially distinct from their natural ligand binding site (orthosteric site), termed as allosteric sites. Read more
 Supervisors: Dr I Tikhonova, Dr B Plouffe
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Funded PhD - The mechanisms of cognition in bees and flies

University of Bristol School of Physiology, Pharmacology & Neuroscience
This project will be part of the Bristol-Macquarie Cotutelle Programme, funded by EPSRC. Read more
 Supervisor: Prof J Hodge
 1 August 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Development of chemical tools and bioactive compounds to explore the importance of enzyme activity in cancer diseases

University of Bradford Faculty of Life Sciences
Diversity-oriented synthesis (DOS) is a modern chemical methodology, which aims to synthesise small molecules that cover new chemical space with the possibility of finding unexplored biological targets or pathways that may be important for disease progression. Read more
 Supervisors: Prof K Pors, Dr V Vangala
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents

University of Bradford Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs). Read more
 Supervisors: Prof R Falconer, Dr S Shnyder
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MScR - Advancing novel methods of assessing apathy-related behaviour in rodents

University of Bristol School of Physiology, Pharmacology & Neuroscience
Apathy is a multidimensional syndrome consisting of behavioural, emotional and cognitive components that ultimately lead to a loss of motivation to engage with daily life. Read more
 Supervisors: Prof E S J Robinson, Dr M Jackson
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Pharmacology of ion channels in human genetic disorders

University of Leeds Faculty of Biological Sciences
The School of Biomedical Sciences invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more
 Supervisors: Dr J D Lippiat, Dr S Clapcote, Dr K Simmons, Dr S Muench
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Funded PhD - Determining the genetic and circadian basis of bipolar disorder

University of Bristol School of Physiology, Pharmacology & Neuroscience
This project will be part of the University of Bristol - University of Kent Cotutelle Programme. It will be jointly supervised by Prof James Hodge (http://www.bristol.ac.uk/phys-pharm-neuro/people-new/hodge/) and Dr Alice French at the University of Bristol, and by Prof Gurprit Lall at University of Kent. Read more
 Supervisors: Prof J Hodge, Dr AF French
 12 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Dissecting behaviourally relevant feedback microcircuits in the brain

Queen Mary University of London Blizard Institute
Interactions between distinct neural circuits in the brain help in sensory-guided perceptual decisions. We have recently reported that task/context-switching behaviour is dependent upon specific populations of neurons in the frontal cortex which encode and convey rule-related information (Banerjee et al. Read more
 Supervisor: Prof A.B Banerjee
 10 May 2024  PhD Research Project  Funded PhD Project (European/UK Students Only)
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Targeting the MAPK scaffold protein KSR1 for the treatment of prostate cancer

University of Bradford Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Prostate cancer is one of the leading causes of male cancer deaths. It arises when individual cells escape their normal growth control mechanisms and proliferate in an uncontrolled fashion. Read more
 Supervisors: Dr J Muller, Prof R Falconer
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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SLS SF3: PhD in Pharmacological intervention of ion channels for the treatment of cardiac disease

University of Westminster School of Life Sciences
Within our lab we study human ion channels, mainly potassium channels, that contain genetic mutations which lead to disease states. Read more
 Supervisors: Dr KP Cunningham, Dr S Getting, Dr DG Gaze
 17 May 2024  PhD Research Project  Self-Funded PhD Students Only
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Pharmacokinetics Guided Natural Products Exploration for Drug Discovery, Development, Delivery and Therapy

University of Bradford Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Natural products have emerged as a key standard in novel and safe delivery of anticancer bioactive compounds. Apart from their ease of administration and delivery, natural/phytochemicals still face several hurdles, due to their physiochemical and pharmacokinetic properties. Read more
 Supervisor: Dr Muhammad Wahajuddin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Polysialyltransferases as a target in metastatic cancer

University of Bradford Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases. Read more
 Supervisors: Prof R Falconer, Dr S Shnyder
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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New Drugs for Brain Tumours: Prodrugs of Diazopropyne

University of Bradford Faculty of Life Sciences
  Research Group: Medicines Development and Pharmaceutical Sciences
The propargyl group, introduced to temozolomide-like drugs for brain tumours by our colleagues in Nottingham, shows considerable pre-clinical promise and… Read more
 Supervisors: Dr R Wheelhouse, Dr S Shnyder
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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New Drugs for Brain Tumours: Defining the Physicochemical Parameters for Optimal Imidazotetrazine (Temozolomide) Derivative Prodrug Activation Kinetics

University of Bradford Faculty of Life Sciences
  Research Group: Medicines Development and Pharmaceutical Sciences
The imidazotetrazine ring system that forms the core of the anticancer drug temozolomide is a fascinating prodrug delivery device. Read more
 Supervisors: Dr R Wheelhouse, Dr S Shnyder, Dr A Ramachandra Kurup Sasikala
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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New Drugs for Brain Tumours: A Locoregional Implant Brain Tumours

University of Bradford Faculty of Life Sciences
  Research Group: Medicines Development and Pharmaceutical Sciences
Next-generation temozolomide derivatives for the treatment of high-grade glioma have been developed at the University of Bradford. Read more
 Supervisors: Dr R Wheelhouse, Prof A Paradkar, Dr S Shnyder
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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