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Pharmacology / Toxicology (death) PhD Projects, Programs & Scholarships

We have 22 Pharmacology / Toxicology (death) PhD Projects, Programs & Scholarships

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We have 22 Pharmacology / Toxicology (death) PhD Projects, Programs & Scholarships

Cutting off the fuel supply to calcium pumps in pancreatic cancer: a novel therapeutic strategy

Background and Rationale. Pancreatic ductal adenocarcinoma (PDAC) has the poorest survival and limited treatment options. Therefore, the search for novel therapeutic targets and drugs designed to selectively kill PDAC cells must remain a central research strategy. Read more

Property based design of mitochondria targeted molecules

Applications are invited from Graduates in Chemistry, Pharmacy and Medicinal Chemistry Master’s level programs to join our group within the Faculty of Medical Sciences looking at novel approaches to the design of the next generation of mitochondria targeted therapeutic agents. Read more

Elphinstone Scholarship - Novel drug targets for pulmonary arterial hypertension: dissecting the phosphodiesterase 1 signalsome

Pulmonary arterial hypertension (PH), which is high blood pressure in the lung, is characterized by increased pulmonary artery smooth muscle cells (PASMC) in the walls of the blood vessels, raised pulmonary vascular resistance, right ventricular failure and premature death. Read more

Effects of glucocorticoid receptor antagonism on immune and tumour biology

Metastatic cancers are the deadliest of diseases with a low chance of survival. In women, metastatic breast cancer is the most frequent causes of cancer death. Read more

Brk and mTOR signalling: implications for Taxol resistance

One of the major causes of death amongst breast cancer patients is due to the development of distal metastases and the acquisition of resistance to chemotherapeutic agents. Read more

Development of a personalized therapy for pulmonary arterial hypertension (PAH)

  Research Group: Pharmacology and Experimental Therapeutics
Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more

Using ex-vivo genetic systems as models to detect genetic susceptibility to co-morbidities in Covid 19 infection, and to test specific anti-inflammatory / antiviral drugs in Covid 19 infection

  Research Group: Chemistry and Biosciences
Research has shown that certain individuals are more susceptible to SARS-CoV-2. Approximately, 20–51% of COVID-19 patients presented with a least one co-morbidity on admission, with diabetes (10–20%) hypertension (10–15%) and other cardiovascular and cerebrovascular diseases (7–40%) being most prevalent. Read more

Impact of RhoA deregulation on smooth muscle cell phenotypic dysfunction in Type 2 diabetes

  Research Group: Chemistry and Biosciences
Type 2 diabetes (T2D) is an escalating healthcare burden. It inflicts significant physical and emotional distress on patients and their carers, and treatment of T2D and its complications accounts for ~10% of the entire NHS budget. Read more

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