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Pharmacology / Toxicology (education) PhD Projects, Programs & Scholarships

We have 10 Pharmacology / Toxicology (education) PhD Projects, Programs & Scholarships

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  Deciphering the role of fat tissues in maintaining systemic glucose and energy metabolism
  Dr K K Y Cheng
Applications accepted all year round

Funding Type

PhD Type

Background. Due to the changes in lifestyle and environment, the incidence of obesity has rapidly increased over the last two decades.
  Development of novel cancer treatments: structural studies of Nectin 4 in complex with bespoke anti-cancer peptides – to start October 2019 - for an MSc by Dissertation (MSD)
  Dr F Prischi, Dr V Bavro
Application Deadline: 1 July 2019

Funding Type

PhD Type

Scientific background. This project targets the current gap in therapeutic approaches targeting Triple Negative Breast Cancer (TNBC) that, unlike other breast cancer subtypes, lacks recommended chemotherapy treatment.
  Defining the role of p53 in cancer immunotherapy
  Prof Y. Haupt, Dr S. Haupt, Dr P. Neeson
Applications accepted all year round

Funding Type

PhD Type

Despite clear evidence of an association between the tumour suppressor p53 and immunity, a gap in knowledge exists regarding its role in modulating immune responses, or its value in predicting patient responses to immunotherapy.
  Development of targeted therapy for acute myeloid leukaemia with mutations in isocitrate dehysdrogenase
  Dr L. Kats
Applications accepted all year round

Funding Type

PhD Type

Acute Myeloid Leukaemia (AML) is an aggressive disease with poor prognosis and development of novel treatment options is urgently needed.
  Exploration of novel approaches to anti-cancer treatment: manipulation of mutant p53
  Prof Y. Haupt, Dr S. Haupt
Applications accepted all year round

Funding Type

PhD Type

P53 is the most mutated gene in human cancer, affecting about half the cases of human cancer. We have recently identified novel regulators of mutant p53 using sophisticated loss of function whole genome high through put screen (image 1).
  Impact of targeted therapy on the melanoma immune microenvironment
  Dr K. Sheppard, Prof G. McArthur
Applications accepted all year round

Funding Type

PhD Type

The treatment of melanoma is undergoing a fundamental change due to the success of both targeted therapies directed at the MAPK/ERK pathway and immunotherapies.
  Inhibition of PRMT5 as a cancer therapy
  Dr K. Sheppard, Prof G. McArthur
Applications accepted all year round

Funding Type

PhD Type

Targeted therapy has had profound impact on outcomes for cancer patients.
  Metabolic Reprogramming in Liver Cancer: delineating the role of reactive oxygen species (ROS) in tumour development
  Prof T. Tiganis
Applications accepted all year round

Funding Type

PhD Type

The Tiganis Laboratory is seeking a highly enthusiastic student to conduct research in cancer metabolism and obesity-associated liver cancer.
  Understanding the role of the lipid bilayer on receptor function
  Dr J Simms, Prof H Maddock
Application Deadline: 31 May 2019

Funding Type

PhD Type

Understanding how the binding of a single ligand influences the behaviour of a membrane protein target is of fundamental importance in drug discovery.
  Epigenetics of Melanoma Immunotherapy Response
  Prof M Eccles, Dr A Chatterjee
Application Deadline: 20 June 2019

Funding Type

PhD Type

Melanoma is a deadly cancer, which accounts for the majority of skin cancer related deaths. Recent development of immunotherapies has had a major impact in the treatment of advanced melanoma.
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