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Pharmacology / Toxicology (entrepreneur) PhD Projects, Programs & Scholarships

We have 7 Pharmacology / Toxicology (entrepreneur) PhD Projects, Programs & Scholarships

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  Identification of novel complement evasion mechanisms developed by bacterial pathogens
  Prof A Blom, Prof S Rooijakkers
Application Deadline: 10 November 2019

Funding Type

PhD Type

The project is focused on discovery of new complement evasion mechanisms developed by bacterial pathogens. One of the studied bacteria will be opportunistic Filifactor alocis, a recently identified periodontal pathogen of major importance but still poorly studied.
  Development of immunoassays for specific classical and lectin pathway activation markers
  Prof Z Prohaszka, Prof R Würzner
Application Deadline: 10 November 2019

Funding Type

PhD Type

Infections and various immune-inflammation mediated conditions are characterized by the activation of the complement system. Antibodies (immune complexes) activate the classical pathway whereas repetitive carbohydrate structures give rise to the initiation of the lectin pathway.
  Complement resistance mechanisms by multi-drug resistant Klebsiella pneumonia
  Prof S Rooijakkers, Prof A Blom
Application Deadline: 10 November 2019

Funding Type

PhD Type

The aim of this project is to characterize complement evasion molecules in the opportunistic bacterium Klebsiella pneumoniae (K. pneumoniae) where carbapenem-resistance grew from 1.6% to 10.4% in 10 years.
  Evaluation of fungal complement evasion mechanisms via the lectin pathway
  Prof P Garred, Prof J Koehl
Application Deadline: 10 November 2019

Funding Type

PhD Type

The group of professor Peter Garred at the University of Copenhagen has deciphered the components of the lectin complement pathway.
  FH, FHR and PTX-3 binding to opportunistic bacteria and malaria parasites
  Prof S Meri, Prof C Garlanda
Application Deadline: 10 November 2019

Funding Type

PhD Type

Infections pose a global threat because of spread of antibiotic resistance, hospital infections and problems in the third world. On the other hand, rapidly increasing information of microbial genomes now provides new opportunities to tackle virulence mechanisms of pathogenic microbes.
  The impact of the MBL pathway on the outcome of infection with representative mycobacterial strains of the Mycobacterium tuberculosis complex
  Dr C Hölscher, Prof S Niemann
Application Deadline: 10 November 2019

Funding Type

PhD Type

Tuberculosis (TB) is the leading cause of death from a single infectious agent which are strains of the Mycobacterium tuberculosis complex (Mtbc).
  Single and double inhibition of complement and CD14 in opportunistic conditions
  Prof T Mollnes, Prof R Würzner, Prof P Garred
Application Deadline: 10 November 2019

Funding Type

PhD Type

The group of professor Mollnes has worked with a combined inhibition of complement (at the level of C3 and C5), and the Toll like receptors (TLRs) targeting CD14, a key co-receptor for TLR4, TLR2 and others, based on an hypothesis to attenuating the upstream innate immune activation when it is over- or dys-activated.
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