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We have 38 Pharmacology (information studies) PhD Projects, Programmes & Scholarships

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Pharmacology (information studies) PhD Projects, Programmes & Scholarships

We have 38 Pharmacology (information studies) PhD Projects, Programmes & Scholarships

The epigenomic, transcriptional and diagnostic architecture of neurodevelopmental disorders caused by exposure to maternal infection

A fundamental unknown in understanding mechanisms of disease, and therefore improving therapy, is how stressors experienced during critical developmental periods influence the genesis or ‘programming’ of adult disease (Estes & McAllister 2016). Read more

Selective targeting of furin for the treatment of fibrotic lung disease.

Furin, a proprotein convertase has been established as a therapeutic target across several disease areas to include chronic airways diseases and infectious disease, such as COVID-19 (reviewed in our recent publication, Douglas et al, 2023). Read more

Transcriptome biomarkers and mechanisms of chemoresistance

Project Summary. This project aims to identify biomarkers linked to the most potent multimodal anticancer therapy with the least toxicity to counteract hemoresistance in head and neck squamous cell carcinoma (HNSCC). Read more

Neurovascular coupling in cerebral hypoperfusion

There are almost a million people living with dementia in the UK. Most of these cases comprise Alzheimer’s Disease (AD), vascular dementia (VaD) or, as is increasingly recognised, a mixed picture phenotype with evidence of the two conditions co-existent in the same patient. Read more

Discovering off-target side-effects and drug repurposing candidates using expression perturbation data

The MRC Integrative Epidemiology Unit at the University of Bristol is the leading group for the development and application of causal analysis and evidence triangulation in health research to improve lives. Read more

MScR: Probing the projections of different types of dopamine neurons

What makes one neuron different from another? How can we define different “types” of cells? Are cell types important?. In Parkinson’s disease some dopamine neurons seem to be more vulnerable to neurodegeneration. Read more

Pharmacological and toxicological effects of pollutants on the cardiovascular system

Faculty of Pharmacy, Charles University, Department of Pharmacology and Toxicology. The majority of the world's population lives in medium or large cities where human activities (industry, transport, etc.) have a direct impact on the production of pollutants. Read more

Beyond the phenotype: Predictors of mental health, sleep and neurobiological outcomes following mild traumatic brain injury

Mild traumatic brain injury (mTBI) is common with 1.4 million hospital visits due to head injury annually in the UK. Although classified as mild it leads to disproportionate impact on future health with 31% unable to work at 12 months. Read more

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