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Pharmacology / Toxicology (investigation) PhD Projects, Programs & Scholarships

We have 8 Pharmacology / Toxicology (investigation) PhD Projects, Programs & Scholarships

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  Endosomal Sorting Complex Required for Transport (ESCRT): Investigation of the role in acquired drug resistance in colon cancer
  Research Group: Institute of Cancer Therapeutics
  Dr S Shnyder, Dr S Kantamneni
Applications accepted all year round

Funding Type

PhD Type

Despite treatment advances, one of the most common cancers, colorectal cancer (CRC), still has a 45% mortality rate, and one of the major problems is the build-up of resistance to cancer drugs during treatment (‘acquired resistance’) such that over time the drugs stop working.
  MRC DTP 4 Year PhD Programme: Interdisciplinary investigation of the role of amino acids in immunometabolic responses to metformin in human macrophages
  Dr G Rena, Prof C Lang
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  Telomere length elongation following treatment with chemotherapeutic drugs. Aim: To investigate the mechanisms which leads to telomere length elongation after treatment with tricostatin A and azacytidine.
  Dr T Roberts
Applications accepted all year round

Funding Type

PhD Type

Telomeres are specialised structures, which are present at the ends of chromosomes and serve to protect the chromosome from degradation during cell division.
  The impact of peri-operative analgesia on neuropharmacological outcomes in rodent models of chronic pain
  Dr K Bannister
Application Deadline: 2 March 2020

Funding Type

PhD Type

A fully funded PhD studentship is available in Dr Kirsty Bannister’s Descending Modulation of Pain Group, King’s College London. The project aim is to research the impact of peri-operative analgesia on rodent neuropharmacological modulation with a specific focus.
  Characterisation of the role of Panx1/Panx2 in primary endothelial cells
  Dr M Boumechache
Applications accepted all year round

Funding Type

PhD Type

Pannexins are a family of proteins that are evolutionary related to the gap-junction forming proteins, innexins (1). Three members have been identified, Panx1, Panx2 and Panx3, and they show distinct tissue distribution.
  Immunity to Influenza and Ebola viruses
  Prof A Townsend
Application Deadline: 24 July 2020

Funding Type

PhD Type

This started with the investigation of T cell recognition of peptides derived from intracellular proteins of Influenza (Townsend et al 1986), that evolved into the development of a live attenuated, single cycle Influenza vaccine, based on these principles (Powell et al, 2012; Baz et al, 2015, Holzer 2018).
  Immunity to Influenza and Ebola viruses
  Prof A Townsend
Application Deadline: 24 July 2020

Funding Type

PhD Type

This started with the investigation of T cell recognition of peptides derived from intracellular proteins of Influenza (Townsend et al 1986), that evolved into the development of a live attenuated, single cycle Influenza vaccine, based on these principles (Powell et al, 2012; Baz et al, 2015, Holzer 2018).
  Development of unique calcium channel pharmacological modulators
  Prof G Monteith, Dr B Ross
Application Deadline: 20 March 2020

Funding Type

PhD Type

This PhD project aims to develop isoform-specific modulators of a family of calcium permeable ion channels, which are prospective drug targets for various diseases.
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