Pharmacology (social science) PhD Projects, Programmes & Scholarships

Supervisors: Dr R Wheelhouse, Prof A Paradkar, Dr S Shnyder

Research Group: Medicines Development and Pharmaceutical Sciences

Next-generation temozolomide derivatives for the treatment of high-grade glioma have been developed at the University of Bradford. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

Breaking the resistance: alternative approaches to antibiotics discovery

Supervisor: Prof G Wagner

The World Health Organisation (WHO) identifies antimicrobial resistance (AMR) as one of the top 10 global threats to human health (http://www.who.int/). Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

The University of Manchester Faculty of Biology, Medicine and Health

Adverse Events to Methotrexate in Inflammatory Arthritis: Does Age Matter?

A consistent top-5 research priority for both children and adults with inflammatory arthritis is the tailoring of treatments to prevent or lessen adverse events. Read more

Supervisors: Dr S Shoop-Worrall, Prof K Hyrich, Dr S Verstappen

Year round applications PhD Research Project Self-Funded PhD Students Only

Targeting the MAPK scaffold protein KSR1 for the treatment of prostate cancer

Supervisors: Dr J Muller, Prof R Falconer

Research Group: Institute of Cancer Therapeutics

Prostate cancer is one of the leading causes of male cancer deaths. It arises when individual cells escape their normal growth control mechanisms and proliferate in an uncontrolled fashion. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

Pharmacokinetics Guided Natural Products Exploration for Drug Discovery, Development, Delivery and Therapy

Supervisor: Dr Muhammad Wahajuddin

Research Group: Institute of Cancer Therapeutics

Natural products have emerged as a key standard in novel and safe delivery of anticancer bioactive compounds. Apart from their ease of administration and delivery, natural/phytochemicals still face several hurdles, due to their physiochemical and pharmacokinetic properties. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

New Drugs for Brain Tumours: Prodrugs of Diazopropyne

Supervisors: Dr R Wheelhouse, Dr S Shnyder

Research Group: Medicines Development and Pharmaceutical Sciences

The propargyl group, introduced to temozolomide-like drugs for brain tumours by our colleagues in Nottingham, shows considerable pre-clinical promise and… Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

New Drugs for Brain Tumours: Defining the Physicochemical Parameters for Optimal Imidazotetrazine (Temozolomide) Derivative Prodrug Activation Kinetics

Supervisors: Dr R Wheelhouse, Dr S Shnyder, Dr A Ramachandra Kurup Sasikala

Research Group: Medicines Development and Pharmaceutical Sciences

The imidazotetrazine ring system that forms the core of the anticancer drug temozolomide is a fascinating prodrug delivery device. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

Biomaterial coatings with lubricious, slippery coatings for improved urinary catheter performance

Supervisors: Dr M Wylie, Prof C McCoy

Intermittent urinary catheterisation is commonly used to address chronic urinary retention in patients suffering from conditions such as spinal cord injury, stroke, and multiple sclerosis. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

Designing next-generation urinary catheter materials for clean intermittent self-catheterisation through control of the urinary microbiome

Supervisors: Dr M Wylie, Dr L Sherrard

Intermittent urinary catheterisation is commonly used to address chronic urinary retention in patients suffering from conditions such as spinal cord injury, stroke, and multiple sclerosis. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

University of Reading Department of Biomedical Sciences

How do hormones regulate memory?

Deficiencies of thyroid hormone are common throughout the globe. Adult-onset hypothyroidism is prevalent in around 8-10% of the population and is associated with reproductive disorders, anxiety, depression and impairment of memory. Read more

Supervisors: Dr N Vasudevan, Prof P G Knight

Year round applications PhD Research Project Self-Funded PhD Students Only

University of Reading Department of Biomedical Sciences

Understanding the molecular mechanisms of thrombosis and haemostasis

Project Overview: . The risk of heart attack or stroke is elevated in obesity and in people with metabolic disorders such as diabetes. Read more

Supervisors: Dr C.E. Hughes, Prof J M Gibbins

Year round applications PhD Research Project Self-Funded PhD Students Only

University of Reading Department of Biomedical Sciences

Using CRISPR in iPS cells to modify platelet function

Project Overview. Platelets are the small cells in the blood whose job it is to prevent bleeding. Under normal conditions, when they encounter a damaged blood vessel they become activated and form a thrombus. Read more

Supervisor: Dr C.E. Hughes

Year round applications PhD Research Project Self-Funded PhD Students Only

Self-Navigating Nanocarriers for Intracellular Protein Delivery

Supervisor: Dr W Al-Jamal

Protein-based therapeutics have shown remarkable success in modulating extracellular targets; however, effective intracellular delivery remains a key challenge in biotherapeutics. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

University of Reading Department of Biomedical Sciences

Examining the mechanisms that cause cardiovascular disease by studying the heart or adipose tissue

Heart failure has a serious impact on our society and once diagnosed has a poor survival rate. In the United Kingdom, there are about 1.5 million people living with the after-effects of a heart attack. Read more

Supervisor: Dr S Boateng

Year round applications PhD Research Project Self-Funded PhD Students Only

University of Reading Department of Ecology and Evolutionary Biology

Evolutionary Perspectives on Medicinal Plant Use

Project Overview. This project uses phylogenetic comparative methods to characterise medicinal plant use. You will use published data to identify the ethnobotanical uses of selected species, and the extent to which they are characterised in terms of phytochemistry and pharmacology. Read more

Supervisor: Prof J A Hawkins

Year round applications PhD Research Project Self-Funded PhD Students Only