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We have 22 Pharmacology (structure) PhD Projects, Programmes & Scholarships

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Pharmacology (structure) PhD Projects, Programmes & Scholarships

We have 22 Pharmacology (structure) PhD Projects, Programmes & Scholarships

Structure-based design of allosteric modulators for G protein-coupled receptors using molecular modelling and pharmacology experiments

Almost all physiological processes are regulated through the activation of G protein-coupled receptors (GPCRs). It has become widely accepted that most GPCRs possess binding sites spatially distinct from their natural ligand binding site (orthosteric site), termed as allosteric sites. Read more

Biological role of neuropeptides and their receptors

Cell signalling is critical to the co-ordination and functioning of all cells. Cell signalling allows cells to co-ordinate activities within the intracellular environment as well as ensuring cells know how to correctly respond to other cells and to an ever-changing extracellular environment as well. Read more

Pharmacological effects of cannabidiol (CBD) on mesenchymal stem cells in endometriosis

Endometriosis is a common long-term health condition that affects around 190 million women of reproductive age worldwide. It causes severe pain during periods, sex, going to the toilet, and sometimes just general pelvic discomfort, bloating, and tiredness. Read more

Using lipid nano-particles to study G-protein-coupled receptors (GPCRs).

This exciting PhD project in the laboratory of Professor Mark Wheatley, Professor of Biochemical Pharmacology is a joint PhD between Coventry University and Stellenbosch University with the student being registered for a PhD at both universities. Read more

Therapeutic resolution of coronavirus (COVID-19) diseases by natural products

  Research Group: Pharmacology and Experimental Therapeutics
Coronavirus now labelled as Covid-19 has become a global pandemic affecting around 200 countries. Currently neither any cure nor any vaccine for Covid-19 has been established. Read more

Synthetic Protein-Transporters for Enhanced Transduction Activity

Intracellular protein delivery is key to probing important cellular processes and developing advanced biotherapeutics. However, protein trafficking into the cell, and more specifically to the cytosol remains a significant challenge. Read more

Investigating the role of P2X7 receptor intracellular domains in cell signalling

Project description. P2X7 receptors are ion channels that are found on the surface of immune cells, where they respond to the binding of extracellular ATP, a damage signal released by dying cells in infection and injury. Read more

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