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Pharmacology / Toxicology (t cell) PhD Projects, Programs & Scholarships

We have 8 Pharmacology / Toxicology (t cell) PhD Projects, Programs & Scholarships

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  Exploring the influence of treatment on CD4+ T-cell sub-populations in patients receiving biologic drugs for their inflammatory arthritis
  Prof A Barton, Dr D Plant, Dr S Viatte
Applications accepted all year round

Funding Type

PhD Type

Background. Tumour necrosis factor inhibitor (TNFi) therapy is ineffective for approximately 20% of rheumatoid arthritis (RA) patients and there is currently no way to predict which patients will not benefit.
  Immunity to Influenza and Ebola viruses
  Prof A Townsend
Application Deadline: 10 January 2020

Funding Type

PhD Type

This started with the investigation of T cell recognition of peptides derived from intracellular proteins of Influenza (Townsend et al 1986), that evolved into the development of a live attenuated, single cycle Influenza vaccine, based on these principles (Powell et al, 2012; Baz et al, 2015, Holzer 2018).
  Immunity to Influenza and Ebola viruses
  Prof A Townsend
Application Deadline: 10 January 2020

Funding Type

PhD Type

This started with the investigation of T cell recognition of peptides derived from intracellular proteins of Influenza (Townsend et al 1986), that evolved into the development of a live attenuated, single cycle Influenza vaccine, based on these principles (Powell et al, 2012; Baz et al, 2015, Holzer 2018).
  BBSRC EASTBIO PhD Programme: Investigating therapeutic targeting of the mRNA cap methyltransferases
  Prof V Cowling, Dr D W Gray
Application Deadline: 5 January 2020

Funding Type

PhD Type

This 4 year PhD project is part of a competition funded by EASTBIO BBSRC Doctoral Training Partnership http://www.eastscotbiodtp.ac.uk/how-apply-0.
  MRC DiMeN Doctoral Training Partnership: Use of 3D skin models and patient-derived immune cells to elucidate the molecular mechanisms of skin detachment in severe drug-induced skin adverse reactions
  Dr D Carr, Prof D Naisbitt, Prof A Dickinson
Application Deadline: 6 January 2020

Funding Type

PhD Type

Background. Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening skin adverse drug reactions which can be caused by a multitude of prescriptions drugs.
  Understanding differential responses to retinoid treatments in human health and disease: a precision medicine approach
  Prof R Watson, Dr A Langton
Applications accepted all year round

Funding Type

PhD Type

Retinoids, such as all-trans retinoic acid (t-RA), are endogenous signalling molecules derived from vitamin A that influence a variety of cellular processes through mediation of transcription events in the cell nucleus.
  (MRC DTP) Insulin-mediated antimicrobial secretion from pancreatic acinar cells regulates the gut microbiome and barrier function: Link between diabetes and severity of acute pancreatitis
  Dr J Bruce, Prof I Roberts, Dr J Pennock
Application Deadline: 15 November 2019

Funding Type

PhD Type

Acute pancreatitis is a serious and sometimes fatal inflammatory disease of the pancreas. Severe cases are characterised by infected pancreatic necrosis, sepsis and multiple organ failure, which increases mortality and prolongs critical care occupancy.
  EASTBIO: Towards a systems-level understanding of visually-guided reaching
  Dr I Duguid, Dr M H Henning
Application Deadline: 5 January 2020

Funding Type

PhD Type

Reaching and grasping is an essential component of our everyday lives. We use visual information regarding object type and position and combine this with exquisite and adaptable motor control to successfully interact with objects in our environment.
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