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We have 21 Pharmacology (death) PhD Projects, Programmes & Scholarships

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Pharmacology (death) PhD Projects, Programmes & Scholarships

We have 21 Pharmacology (death) PhD Projects, Programmes & Scholarships

Inducing ferroptotic death to kill cancer cells

Ferroptosis is an iron-dependent form of regulated necrotic cell death triggered by oxidative degradation of lipids in membrane bilayers and subsequent irreparable damages to the plasma membrane (1). Read more

SLS 3: Investigating the anti-inflammatory effects of artemisinin compounds on macrophages under systemic inflammatory conditions

Artemisinin compounds are safe and effective antimalarials. Recent evidence in our lab has shown these compounds also exert a potent anti-inflammatory effect by inhibiting neutrophil migration and the release of cytokines, chemokines and neutrophil extracellular traps. Read more

Development of miRNAs as a new therapeutic tool in the treatment of cardiovascular diseases

Ischemic heart diseases and their pathological consequences belong to the leading causes of death worldwide. In the acute treatment of myocardial ischemia one of the most important tasks is the restoration of the tissue perfusion. Read more

(MRC DTP CASE) Understanding how tumour associated macrophages control the tumour immune landscape in NF2-Schwannomatosis

Type 2 Neurofibromatosis (NF2), now referred to as NF2-Schwannomatosis (or NF2-SWN), is a rare autosomal dominant tumour pre-disposition syndrome characterised by growth of typically benign tumours throughout the nervous system. Read more

Therapeutic resolution of pulmonary arterial hypertension (PAH) by natural products

  Research Group: Pharmacology and Experimental Therapeutics
Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more

Development of a personalized therapy for pulmonary arterial hypertension (PAH)

  Research Group: Pharmacology and Experimental Therapeutics
Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more

Re-purposing established drugs for the resolution of pulmonary arterial hypertension (PAH)

  Research Group: Pharmacology and Experimental Therapeutics
Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more

Developing novel therapeutic strategies to better treat Triple Negative Breast Cancer

One in two people will develop cancer in their lifetime and it is a leading cause of death.  While significant progress has been made in the treatment of some cancers, there still remain some forms of the disease with limited treatment options and poor outcome. . Read more

Personalising cancer treatment with tumour evolution modelling using AI-based genomics biomarkers and PK/PD

Tumour heterogeneity is a major problem limiting the efficacy of targeted oncological therapies. Most advanced tumours eventually become resistant to the treatments, ultimately making the patient succumb to metastatic disease. Read more

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