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Pharmacology / Toxicology (flow cytometry) PhD Projects, Programs & Scholarships

We have 11 Pharmacology / Toxicology (flow cytometry) PhD Projects, Programs & Scholarships

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  Characterising B cells in Rheumatoid Arthritis: Their role in susceptibility, pathogenesis, and treatment response
  Dr S Viatte, Dr Gemma Radley, Prof A Barton
Applications accepted all year round

Funding Type

PhD Type

Background. Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that primarily affects the joints. In the UK, some patients who fail to respond to methotrexate (MTX) and TNF inhibitors (TNFi) are started on rituximab, and 20% will experience a favourable clinical response.
  MRC DiMeN Doctoral Training Partnership: Design and Optimisation of Red/NIR Fluorescent Dyes for the Assessment of Antimicrobial Susceptibility
  Prof D Kell, Dr G Nixon
Application Deadline: 6 January 2020

Funding Type

PhD Type

The current anti-microbial resistance (AMR) crisis is well documented and the need for a very rapid antibiotic susceptibility test is key to preventing mis-diagnosis and subsequent mis-prescribing.
  Therapeutic targeting of chemokines in inflammation
  Prof S Bhattacharya
Application Deadline: 10 January 2020

Funding Type

PhD Type

Inflammation, driven by leucocytes, adversely affects organ function in diseases such as myocarditis, myocardial infarction, acute lung injury, sepsis and pancreatitis,.
  The molecular mechanisms of thrombosis and haemostasis
  Dr C.E. Hughes
Applications accepted all year round

Funding Type

PhD Type

A healthy cardiovascular system relies on the cells lining the blood vessels (endothelial cells) and heart cells (cardiomyocytes) to function normally.
  Structure based design of novel warheads for use in peptide-drug conjugates
  Dr S Butterworth, Dr A Tirella, Dr D Wiseman
Applications accepted all year round

Funding Type

PhD Type

Chronic Myelomonocytic Leukaemia (CMML) is an orphan disease defined by myeloid dysplasia, myeloproliferation and a malignant expansion of classical monocytes.
  Wellcome-MRC Cambridge Stem Cell Institute 4-year PhD Studentships

Funding Type

PhD Type

The University of Cambridge is exceptional in the depth and diversity of its research in Stem Cell Biology, and has a dynamic and interactive research community that is ranked amongst the foremost in the world.
  Feeding gut stem cells to keep them healthy (SOBOLEWSKIAU20SCIEC)
  Dr A Sobolewski, Prof M O'Connell
Application Deadline: 30 June 2020

Funding Type

PhD Type

A normal functioning epithelium is vital for a healthy gut. The epithelium forms a protective barrier between bacteria in the intestine & the underlying immune system, so preventing an immune response.
  More than skin-deep: the role of LC3-associated phagocytosis in epidermal pigmentation (MORRISCU20SCIO)
  Dr C Morris, Prof T Wileman
Application Deadline: 30 January 2020

Funding Type

PhD Type

The epidermis serves a number of key functions in maintaining human health. The production of the skin pigment, melanin, is triggered in response to UV radiation and serves to protect the skin from UV-induced DNA damage that causes premature ageing and predisposes to skin cancer.
  Modulation of platelet-mediated innate immune responses in chronic lymphocytic leukaemia
  Dr M Arman
Application Deadline: 31 March 2020

Funding Type

PhD Type

Chronic lymphocytic leukaemia (CLL) is the most common form of leukaemia in the Western World. B-cell receptor-induced intracellular signals are critical for the survival of leukaemia cells and disruption of this pathway by the Bruton’s tyrosine kinase (Btk) inhibitor ibrutinib is a highly effective CLL therapy.
  Platelets and hypoxia: how do varying oxygen concentrations affect platelet function and signalling?
  Dr M Arman
Applications accepted all year round

Funding Type

PhD Type

Platelets have key functions in regulating haemostasis and maintaining vascular integrity, which can cause cardiovascular disease if unbalanced.
  Using CRISPR in iPS cells to modify platelet function
  Dr C.E. Hughes
Applications accepted all year round

Funding Type

PhD Type

"Platelets are the small cells in the blood whose job it is to prevent bleeding. Under normal conditions, when they encounter a damaged blood vessel they become activated and form a thrombus.
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