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Pharmacology / Toxicology (human) PhD Projects, Programs & Scholarships

We have 62 Pharmacology / Toxicology (human) PhD Projects, Programs & Scholarships

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  Mechanism of interaction between phosphodiesterase type 5 inhibitors and selective oestrogen receptor modulators in human fibroblasts
  Prof S Cellek, Prof D Ralph
Application Deadline: 9 February 2020

Funding Type

PhD Type

This project is supported by colleagues in MTRC. Fibrosis is the overproduction of extracellular matrix proteins which can impedes the function of organs.
  Our Mission: to Educate, Nurture and Discover for the benefit of Human Health

Funding Type

PhD Type

Our ultimate purpose is to work in service of patients. RCSI was founded by Royal Charter on 11th February 1784, to set and support professional standards for surgical training and practice in Ireland.
  Understanding differential responses to retinoid treatments in human health and disease: a precision medicine approach
  Prof R Watson, Dr A Langton
Applications accepted all year round

Funding Type

PhD Type

Retinoids, such as all-trans retinoic acid (t-RA), are endogenous signalling molecules derived from vitamin A that influence a variety of cellular processes through mediation of transcription events in the cell nucleus.
  Precision-cut lung slices to investigate the effect of human rhinovirus on cough and airway inflammation
  Dr L Sadofsky
Application Deadline: 31 March 2020

Funding Type

PhD Type

The human Rhinovirus (RV) is the major cause of the common cold. There are no current treatments or vaccines for the virus other than over the counter preparations to alleviate symptoms.
  MSc by Research Programme: Assessment of plated cryopreserved hepatocytes as a tool to accurately determine the intrinsic clearance of low metabolism compounds
  Dr K Read
Application Deadline: 16 July 2020

Funding Type

PhD Type

This course allows you to work alongside our world renowned experts from the School of Life Sciences and gain a ’real research’ experience.
  Precision Medicine DTP - An integrated computational-experimental approach to identify and optimise combination drug therapy for non-alcoholic fatty liver disease (NAFLD)
  Research Group: Centre for Inflammation Research
  Prof J Fallowfield, Dr F Menolascina, Prof J Plevris
Application Deadline: 8 April 2020

Funding Type

PhD Type

Background. Non-alcoholic fatty liver disease (NAFLD) is the commonest cause of chronic liver disease (CLD), affecting 1 in 4 people worldwide.
  Electrophysiological changes in ion channels in human haploid and diploid (spermatozoa and lymphocytes) after nanoparticle exposure
  Research Group: Chemistry and Biosciences
  Dr L Shang, Dr M H Brinkworth, Prof D Anderson
Applications accepted all year round

Funding Type

PhD Type

Nanomaterial-mediated delivery represents a promising technique for repro- and geno- toxicology with a potential to improve the safety and efficacy of existing methodologies, including experimental gene therapy and sperm-mediated gene transfer.
  (BBSRC DTP CASE) Exploitation of P450 BM3 variants for production of valuable drug metabolites
  Prof A Munro, Prof D Leys
Application Deadline: 31 January 2020

Funding Type

PhD Type

The US Food and Drug Administration (FDA) have recommended that human drug metabolites (as well as their parent drugs) should be subject to testing for safety/toxicity.
  Investigating the role of bioactive lipids in skin health
  Prof A Nicolaou, Prof C A O'Neill
Applications accepted all year round

Funding Type

PhD Type

Human skin depends on systemic provision of fatty acids that are important to maintain the integrity of the epidermal barrier as well as to support the associated immune and inflammatory reactions.
  The role of gankyrin as a fertility sparing therapy in children with cancer and men with testicular germ cell tumours.
  Dr R Mitchell, Prof N Carragher
Application Deadline: 26 January 2020

Funding Type

PhD Type

The newly established four-year Medical Sciences & Translational Research PhD with integrated studies in Engagement for Impact Programme will combine medical…
  PhD Studentship Opportunity in Computational modelling of skin absorption of chemicals
  Dr T Chen, Prof G Lian
Application Deadline: 29 February 2020

Funding Type

PhD Type

Human skin is a complex organ of human body with multilayer tissues and multiple components such as sweat ducts and glands, sebaceous glands and hair follicles.
  Fully Funded Public Health England PhD Scholarship: Use of advanced multi-cellular models of the human respiratory system to investigate the mechanistic effects of particulate and gaseous air pollutants
  Dr M Clift
Application Deadline: 31 January 2020

Funding Type

PhD Type

This scholarship is funded by Public Health England (PHE). Start date. April 2020. Subject areas. In Vitro Systems; In Vivo Models; Cell Biology; Cell Culture; Toxicology; Air Pollution; Particulate; NO2.
  Development of a three dimensional in vitro model of the human cornea to dissect the inflammatory events associated with sight-threatening ocular pathogens
  Dr C Dobson, Dr C Maldonado-Codina, Prof P Morgan
Applications accepted all year round

Funding Type

PhD Type

The presence of microbes at the corneal surface may trigger low grade discomfort through to acute eye infection and permanent loss of vision.
  Proteomics to determine how defects in membrane trafficking within the secretory pathway cause human disease
  Prof M Lowe, Prof V Allan
Applications accepted all year round

Funding Type

PhD Type

Work in the Lowe laboratory is aimed at deciphering the molecular mechanisms that control membrane trafficking within cells. A major focus of our work is the trafficking of proteins to and through the Golgi apparatus, which lies at the heart of the secretory pathway.
  Impact of normal and premature ageing on human macro- and microvasculature
  Research Group: Centre for Skin Sciences
  Dr K Riches-Suman, Dr M J Thornton
Applications accepted all year round

Funding Type

PhD Type

The global population is growing, with the number of births consistently higher than the number of deaths. This is because people are living for longer, due at least in part to improved lifestyle and healthcare provision.
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