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Pharmacology / Toxicology PhD Projects, Programs & Scholarships

We have 138 Pharmacology / Toxicology PhD Projects, Programs & Scholarships

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  Images in the medical and life sciences
  Dr U Stegmann, Dr L Moretti
Applications accepted all year round

Funding Type

PhD Type

Pictorial representations and images (e.g. photographs and diagrams) are common in the medical and life sciences. Examples include fMRI images and micrographs.
  Development of ex vivo tissue culture models for developing next-generation biomaterial scaffolds for acellular regenerative medicine.
  Prof I Gibson, Prof N Vargesson
Applications accepted all year round

Funding Type

PhD Type

Bone repair and regeneration can be influenced by various guidance cues, including pharmacological cues, hypoxia environment and chemical cues released from scaffolds [1-3].
  EPSRC Centre for Doctoral Training in Engineered Tissues for Discovery, Industry and Medicine (LifETIME)

Funding Type

PhD Type

The CDT will train the next generation of leaders in developing in vitro tissues, sensing and diagnostics to develop humanised in vitro systems to drive better drug screening.
  Disrupting the regulatory mechanisms that allow hospital acquired infections to resist antibiotic therapy.
  Dr R McCarthy
Applications accepted all year round

Funding Type

PhD Type

The discovery of penicillin over 90 years ago and its subsequent uptake by healthcare systems around the world revolutionised global health and wellbeing.
  Inhibiting cell metabolism to enhance tumour cell death
  Dr C Bubici, Dr S Papa
Application Deadline: 31 January 2020

Funding Type

PhD Type

As you read this, millions of your cells from your body are dying. Do not panic – this is not bad news. Most of them are either superfluous or potentially harmful, so you are better off without them.
  Nanoparticles in drug delivery
  Dr G Stenbeck, Dr U Kishore
Applications accepted all year round

Funding Type

PhD Type

Nanoparticles (NPs) are materials with overall dimensions in the nano scale range (5nm-100nm). Due to their unique physicochemical properties, they have found a wide range of applications and are currently explored as drug and gene delivery vehicles.
  Telomere length elongation following treatment with chemotherapeutic drugs. Aim: To investigate the mechanisms which leads to telomere length elongation after treatment with tricostatin A and azacytidine.
  Dr T Roberts
Applications accepted all year round

Funding Type

PhD Type

Telomeres are specialised structures, which are present at the ends of chromosomes and serve to protect the chromosome from degradation during cell division.
  Discovering zinc signalling mechanisms to prevent breast cancer progression
  Dr K Taylor
Applications accepted all year round

Funding Type

PhD Type

Zinc is essential for all living cells, yet the true extent of its role is only now emerging and is fully suggestive of a complexity and importance of that attributed to calcium.
  Discovery of novel cancer immunotherapeutic agents
  Dr Y Mehellou
Applications accepted all year round

Funding Type

PhD Type

Although cancer therapeutics, mainly chemotherapy and radiotherapy, have been extremely useful in the treatment of cancer, this disease is still associated with high morbidity and mortality.
  Discovery of novel treatments for Parkinson’s disease
  Dr Y Mehellou, Dr E Lane
Applications accepted all year round

Funding Type

PhD Type

Parkinson’s disease (PD) is the second most common neurological disease in the world. Current PD therapies and medical interventions are very limited and only address the symptoms of this disease highlighting the need for new and effective treatments.
  PhD in Continuous Manufacturing and Advanced Crystallisation

Funding Type

PhD Type

CMAC, the EPSRC Future Manufacturing Research Hub in Continuous Manufacturing and Advanced Crystallisation, is a major initiative that aims to accelerate the adoption of continuous manufacturing technologies for high value chemical products such as pharmaceuticals.
  EPSRC Centre for Doctoral Training (CDT) in Smart Medical Imaging

Funding Type

PhD Type

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  Syntheses and characterization of compounds of forensic interest using novel methodologies/technologies.
  Dr G Dowling
Applications accepted all year round

Funding Type

PhD Type

The successful candidate will initially characterize new psychoactive substances (NPS) of forensic interest and then investigate the syntheses of these compounds, using microscale procedures, where the material is not isolated or characterized but its identity is deduced from spectral data and through certainty given by the synthetic route chosen.
  EPSRC Centre for Doctoral Training (CDT) in Smart Medical Imaging

Funding Type

PhD Type

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  Synthesis and Anti-Cancer Evaluation of New Heterocyclic Quinones
  Prof F Aldabbagh, Dr N Hill
Applications accepted all year round

Funding Type

PhD Type

The group has published on small molecules with specificity towards hypoxic cells associated with solid tumours, reductase enzymes over-expressed in cancer, as well as, aziridines that induce hypersensitivity from Fanconi anaemia cells and those carrying mutations in the BRCA (Breast Cancer Susceptibility) genes.
  Synthesis and identification of homoisoflavonoids and lignans for the treatment of wet active age-related macular degeneration based on their anti-vascular endothelial growth factor and anti-inflammatory activities
  Dr S Schwikkard, Dr E Opara
Applications accepted all year round

Funding Type

PhD Type

Age-related macular degeneration is reported to be the most common cause of visual impairment, and its certification, in the developed world.
  The influence of psychological stress on health and physical performance in British Army Recruits
  Prof N Walsh
Application Deadline: 30 September 2019

Funding Type

PhD Type

PhD Studentship (4 years). Applications are invited for a four-year, full-time PhD studentship supervised by Prof Neil Walsh and his team in the School of Sport and Exercise Sciences, Liverpool John Moores University.
  PhD in Continuous Manufacturing and Advanced Crystallisation

Funding Type

PhD Type

CMAC, the EPSRC Future Manufacturing Research Hub in Continuous Manufacturing and Advanced Crystallisation, is a major initiative that aims to accelerate the adoption of continuous manufacturing technologies for high value chemical products such as pharmaceuticals.
  Identification of novel complement evasion mechanisms developed by bacterial pathogens
  Prof A Blom, Prof S Rooijakkers
Application Deadline: 10 November 2019

Funding Type

PhD Type

The project is focused on discovery of new complement evasion mechanisms developed by bacterial pathogens. One of the studied bacteria will be opportunistic Filifactor alocis, a recently identified periodontal pathogen of major importance but still poorly studied.
  Mass spectrometric imaging of biological tissues
  Prof J Preisler, Ms M Machalkova
Application Deadline: 31 October 2019

Funding Type

PhD Type

Mass spectrometry imaging (MSI) exploits the ability of mass spectrometry to identify molecules according to their specific mass and image their distribution across the sample.
  Open PhD positions - IMPRS for Heart and Lung Research

Funding Type

PhD Type

The International Max Planck Research School for Heart and Lung Research (IMPRS-HLR) offers up to ten positions to talented and enthusiastic students holding a relevant Master‘s degree.
  Creating Materials to Deliver Stem Cell Products
  Dr Mark Del Borgo, Dr Ketav Kulkarni, Prof R Widdop, Prof Mibel Aguilar
Applications accepted all year round

Funding Type

PhD Type

Stem cell therapy holds immense potential as a treatment paradigm for a number of conditions. However, currently the therapeutic outcome is often limited by low cell survivability, poor integration within the host tissue of the stroke brain and non-sustained delivery over the period of treatment.
  EPSRC Centre for Doctoral Training in Engineered Tissues for Discovery, Industry and Medicine (LifETIME)

Funding Type

PhD Type

The CDT will train the next generation of leaders in developing in vitro tissues, sensing and diagnostics to develop humanised in vitro systems to drive better drug screening.
  Inhibition of PRMT5 as a cancer therapy
  Dr K. Sheppard
Applications accepted all year round

Funding Type

PhD Type

Targeted therapy has had profound impact on outcomes for cancer patients.
  Metabolic Reprogramming in Liver Cancer: delineating the role of reactive oxygen species (ROS) in tumour development
  Prof T. Tiganis
Applications accepted all year round

Funding Type

PhD Type

The Tiganis Laboratory is seeking a highly enthusiastic student to conduct research in cancer metabolism and obesity-associated liver cancer.
  Overcoming therapy induced reprogramming of metabolism in melanoma
  Dr K. Sheppard, Dr L Smith
Applications accepted all year round

Funding Type

PhD Type

Therapies that target oncogenes in cancer have revolutionised cancer care. The major benefits of targeted therapies are high response rates and manageable toxicities, however they do not result in cures in the vast majority of patients.
  RNA Methylation in normal and malignant blood development
  Dr L. Kats
Applications accepted all year round

Funding Type

PhD Type

As is the case with DNA and histones, RNA can also be modified and indeed more than 100 chemical groups that decorate all four canonical RNA nucleotides have been described.
  Pre-clinical targets for vascular dementia treatment
  Prof R Fern, Dr E Kramer, Dr K Glebov
Application Deadline: 6 October 2019

Funding Type

PhD Type

MPhil/PhD Studentship available full time and part-time. Project title. Pre-clinical targets for vascular dementia treatment. Reference Number.
  Modelling of Oral Neutrophil Epithelial interactions
  Dr E Hagi-Pavli
Applications accepted all year round

Funding Type

PhD Type

Background and Clinical Significance. Neutrophils are an important and vital cellular component of the innate immune system providing rapid protection against microbial invasion.
  DsbA Foldases from Multidrug Resistant Pathogens as Targets for New Antimicrobials
  Assoc Prof M Totsika
Application Deadline: 20 September 2019

Funding Type

PhD Type

In 2014 the World Health Organization declared antimicrobial resistance a global health priority. With 10 million deaths per year predicted by 2050 due to drug resistant infections, new therapies to tackle multidrug resistant pathogens need to be developed now.
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