Pharmacology (biomedical science) PhD Projects, Programmes & Scholarships

Understanding the molecular mechanisms of thrombosis and haemostasis

University of Reading Department of Biomedical Sciences

Project Overview: . The risk of heart attack or stroke is elevated in obesity and in people with metabolic disorders such as diabetes. Read more

Supervisors: Dr C.E. Hughes, Prof J M Gibbins

Year round applications PhD Research Project Self-Funded PhD Students Only

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Determine the efficacy of growth hormone receptor antagonism in hepatocellular carcinoma spheroid culture models

University of Auckland Liggins Institute

Hepatocellular carcinoma (HCC) is an aggressive and difficult to treat cancer with poor survival rates and limited systemic treatment options for advanced-stage disease. Read more

Supervisors: Dr Y Wang, Dr J Perry

28 February 2025 PhD Research Project Self-Funded PhD Students Only

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Use of a novel conjugation approach to generate a long-acting growth hormone receptor antagonist

University of Auckland Liggins Institute

Targeting the growth hormone (GH) signalling pathway could be an effective therapeutic approach for certain types of cancer. However, a lack of access to therapeutics that target GH or the GH receptor has hindered preclinical studies in this field. Read more

Supervisors: Dr Y Wang, Dr J Perry

30 August 2024 PhD Research Project Self-Funded PhD Students Only

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Possible role of mutant vimentin in cancer progression and metastasis

Queen Mary University of London Institute of Dentistry

Background. This project will investigate the role of the cytoskeletal protein vimentin in cancer progression and metastasis using cell and molecular biology approaches. Read more

Supervisors: Prof A Waseem, Dr F Flores-Borja, Dr H Tummala

Year round applications PhD Research Project Self-Funded PhD Students Only

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Gaining mechanistic insights into Atrial Fibrillation: Bench to bedside approaches

University of Liverpool Department of Pharmacology and Therapeutics

Atrial fibrillation (AF) is a common arrhythmia with symptoms like irregular heart rate, palpitations, shortness of breath, tiredness, and dizziness. Read more

Supervisor: Dr RB Burton

1 July 2024 PhD Research Project Self-Funded PhD Students Only

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MRes in Clinical Science

University of East Anglia Norwich Medical School

Our MRes Clinical Science is your chance to experience the reality of cutting-edge clinical or biomedical research. You’ll develop a broader, more considered approach to a specific area of medical research, gaining expertise in the intellectual and practical skills of scientific research in the process. Read more

Supervisor: Dr K Tyler

Year round applications PhD Research Project Self-Funded PhD Students Only

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Predicting harm from prescribed drugs in people with polypharmacy, multimorbidity and frailty

University of Edinburgh College of Medicine and Veterinary Medicine

The Advanced Care Research Centre (ACRC) is an interdisciplinary, £20M research centre at the University of Edinburgh. Read more

Supervisors: Prof B. Guthrie, Prof J Fleuriot

22 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Using CRISPR in iPS cells to modify platelet function

University of Reading Department of Biomedical Sciences

Project Overview. Platelets are the small cells in the blood whose job it is to prevent bleeding. Under normal conditions, when they encounter a damaged blood vessel they become activated and form a thrombus. Read more

Supervisor: Dr C.E. Hughes

Year round applications PhD Research Project Self-Funded PhD Students Only

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Elucidating the role of lipids in fibrotic capsule formation at the surface of implanted medical devices.

University of Nottingham School of Medicine

Implanted medical devices are crucial in healthcare, valued at around £400 billion globally, however there is a high failure rate, often due to the foreign body reaction, where a fibrotic capsule forms around the implant with associated inflammation, loosening and infection. Read more

Supervisors: Prof M Alexander, Prof AG Ghaemmaghami, Dr D H Kim, Prof BO Ollivere

30 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Infection-responsive coatings for the prevention of catheter-associated urinary tract infections

Queen’s University Belfast School of Pharmacy

Medical care has transformed over the last century with significant improvements in the variety and extent to which various diseases can be treated and/or prevented. Read more

Supervisors: Dr M Wylie, Prof C McCoy

Year round applications PhD Research Project Self-Funded PhD Students Only

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Biomaterial coatings with lubricious, slippery coatings for improved urinary catheter performance

Queen’s University Belfast School of Pharmacy

Intermittent urinary catheterisation is commonly used to address chronic urinary retention in patients suffering from conditions such as spinal cord injury, stroke, and multiple sclerosis. Read more

Supervisors: Dr M Wylie, Prof C McCoy

Year round applications PhD Research Project Self-Funded PhD Students Only

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Designing next-generation urinary catheter materials for clean intermittent self-catheterisation through control of the urinary microbiome

Queen’s University Belfast School of Pharmacy

Intermittent urinary catheterisation is commonly used to address chronic urinary retention in patients suffering from conditions such as spinal cord injury, stroke, and multiple sclerosis. Read more

Supervisors: Dr M Wylie, Dr L Sherrard

Year round applications PhD Research Project Self-Funded PhD Students Only

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How do hormones regulate memory?

University of Reading Department of Biomedical Sciences

Deficiencies of thyroid hormone are common throughout the globe. Adult-onset hypothyroidism is prevalent in around 8-10% of the population and is associated with reproductive disorders, anxiety, depression and impairment of memory. Read more

Supervisors: Dr N Vasudevan, Prof P G Knight

Year round applications PhD Research Project Self-Funded PhD Students Only

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Analysing the role of statins in cardiovascular protection

University of Liverpool Department of Pharmacology and Therapeutics

Drug-induced cardiovascular toxicity is a major problem affecting a number of cancer chemotherapy drugs (Cross et al., 2015). Read more

Supervisors: Dr M Cross, Dr B Wilm, Dr AM Mondru

Year round applications PhD Research Project Self-Funded PhD Students Only

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Development of carbohydrate-functionalised materials for detection and prevention of medical device-associated infections

Queen’s University Belfast School of Pharmacy

Antibiotic-resistant bacteria are a growing problem in the 21st century, causing longer and more serious infections, and resulting in poor outcomes for vulnerable patients. . Read more

Supervisor: Dr M Wylie

Year round applications PhD Research Project Self-Funded PhD Students Only

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Analysis of the role of liver sinusoidal endothelial cells in methotrexate-induced liver toxicity

University of Liverpool Department of Pharmacology and Therapeutics

Liver sinusoidal endothelial cells (LSECs) comprise approximately 50% of the non-parenchymal hepatic cells. They play a vital role in hepatic microcirculation and provide a physiological barrier to the movement of xenobiotics from the bloodstream to hepatic tissue. Read more

Supervisors: Dr M Cross, Prof C Goldring

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigation of novel protease-antiprotease imbalances associated with cystic fibrosis and the effect of CFTR correction.

Queen’s University Belfast School of Pharmacy

Cystic fibrosis (CF) is a progressive life-limiting airways disease that affects over 162,000 people worldwide. Read more

Supervisor: Prof L Martin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Selective targeting of furin for the treatment of fibrotic lung disease.

Queen’s University Belfast School of Pharmacy

Furin, a proprotein convertase has been established as a therapeutic target across several disease areas to include chronic airways diseases and infectious disease, such as COVID-19 (reviewed in our recent publication, Douglas et al, 2023). Read more

Supervisor: Prof L Martin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Tackling health inequity in pharmaceuticals

University College London UCL School of Pharmacy

Tackling health inequity in pharmaceuticals. Research has been increasingly highlighting the disparities in the investigation of gender-specific responses to medicines. Read more

Supervisor: Prof A Basit

Year round applications PhD Research Project Self-Funded PhD Students Only

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Self-Navigating Nanocarriers for Intracellular Protein Delivery

Queen’s University Belfast School of Pharmacy

Protein-based therapeutics have shown remarkable success in modulating extracellular targets; however, effective intracellular delivery remains a key challenge in biotherapeutics. Read more

Supervisor: Dr W Al-Jamal

Year round applications PhD Research Project Self-Funded PhD Students Only

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Examining the mechanisms that cause cardiovascular disease by studying the heart or adipose tissue

University of Reading Department of Biomedical Sciences

Heart failure has a serious impact on our society and once diagnosed has a poor survival rate. In the United Kingdom, there are about 1.5 million people living with the after-effects of a heart attack. Read more

Supervisor: Dr S Boateng

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 21 Pharmacology (biomedical science) PhD Projects, Programmes & Scholarships

Pharmacology (biomedical science) PhD Projects, Programmes & Scholarships

We have 21 Pharmacology (biomedical science) PhD Projects, Programmes & Scholarships

Understanding the molecular mechanisms of thrombosis and haemostasis

Determine the efficacy of growth hormone receptor antagonism in hepatocellular carcinoma spheroid culture models

Use of a novel conjugation approach to generate a long-acting growth hormone receptor antagonist

Possible role of mutant vimentin in cancer progression and metastasis

Gaining mechanistic insights into Atrial Fibrillation: Bench to bedside approaches

MRes in Clinical Science

Predicting harm from prescribed drugs in people with polypharmacy, multimorbidity and frailty

Using CRISPR in iPS cells to modify platelet function

Elucidating the role of lipids in fibrotic capsule formation at the surface of implanted medical devices.

Infection-responsive coatings for the prevention of catheter-associated urinary tract infections

Biomaterial coatings with lubricious, slippery coatings for improved urinary catheter performance

Designing next-generation urinary catheter materials for clean intermittent self-catheterisation through control of the urinary microbiome

How do hormones regulate memory?

Analysing the role of statins in cardiovascular protection

Development of carbohydrate-functionalised materials for detection and prevention of medical device-associated infections

Analysis of the role of liver sinusoidal endothelial cells in methotrexate-induced liver toxicity

Investigation of novel protease-antiprotease imbalances associated with cystic fibrosis and the effect of CFTR correction.

Selective targeting of furin for the treatment of fibrotic lung disease.

Tackling health inequity in pharmaceuticals

Self-Navigating Nanocarriers for Intracellular Protein Delivery

Examining the mechanisms that cause cardiovascular disease by studying the heart or adipose tissue

We have 21 Pharmacology (biomedical science) PhD Projects, Programmes & Scholarships

Pharmacology (biomedical science) PhD Projects, Programmes & Scholarships

We have 21 Pharmacology (biomedical science) PhD Projects, Programmes & Scholarships

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