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Pharmacology / Toxicology (career) PhD Projects, Programs & Scholarships

We have 27 Pharmacology / Toxicology (career) PhD Projects, Programs & Scholarships

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  PhD in Chemical Biology -- Neuropeptide Research -- University of Vienna
  Prof M Muttenthaler
Applications accepted all year round

Funding Type

PhD Type

Neuropeptides are key mediators in many biological functions and understanding their interaction with target proteins is fundamental to unravel the underlying mechanism of diseases.
  Using lipid nano-particles to study G-protein-coupled receptors
  Prof M Wheatley
Application Deadline: 31 March 2020

Funding Type

PhD Type

We are seeking a highly-motivated candidate for this exciting PhD project in the laboratory of Professor Mark Wheatley, Professor of Biochemical Pharmacology.
  Inhibition of PRMT5 as a cancer therapy
  Dr K. Sheppard
Applications accepted all year round

Funding Type

PhD Type

Targeted therapy has had profound impact on outcomes for cancer patients.
  Metabolic Reprogramming in Liver Cancer: delineating the role of reactive oxygen species (ROS) in tumour development
  Prof T. Tiganis
Applications accepted all year round

Funding Type

PhD Type

The Tiganis Laboratory is seeking a highly enthusiastic student to conduct research in cancer metabolism and obesity-associated liver cancer.
  RNA Methylation in normal and malignant blood development
  Dr L. Kats
Applications accepted all year round

Funding Type

PhD Type

As is the case with DNA and histones, RNA can also be modified and indeed more than 100 chemical groups that decorate all four canonical RNA nucleotides have been described.
  Fostering development of ‘smart’, responsive therapeutics against cancer-related microRNAs.
  Dr E Bichenkova, Prof D Clarke, Dr H Aojula
Applications accepted all year round

Funding Type

PhD Type

Short functional non-coding microRNAs are implicated in many types of cancer, and thus can be used as biological targets for development of more selective and powerful anticancer therapies.
  Modelling a myelination disorder in the zebrafish: drug discovery and gene editing
  Prof T T Whitfield
Application Deadline: 31 March 2020

Funding Type

PhD Type

Adhesion G protein-coupled receptors (aGPCRs) have exciting potential as therapeutic targets for drug discovery. The aGPCR Adgrg6 (Gpr126) has a conserved role in myelination of the vertebrate peripheral nervous system, and is of considerable clinical interest.
  PhD position/Graduate Research Assistantship in the area of Allergy, Asthma and Immunology
  Dr A Mishra
Applications accepted all year round

Funding Type

PhD Type

The Laboratory of Lung Inflammation, Department of Pathobiology, College of Veterinary Medicine at Auburn University have opening for highly motivated PhD candidate/ Graduate Research Assistant to work on NIH-funded research project in the area of Allergy, Asthma and Immunology.
  Discovery of novel cancer immunotherapeutic agents
  Dr Y Mehellou
Applications accepted all year round

Funding Type

PhD Type

Although cancer therapeutics, mainly chemotherapy and radiotherapy, have been extremely useful in the treatment of cancer, this disease is still associated with high morbidity and mortality.
  EPSRC Centre for Doctoral Training (CDT) in Smart Medical Imaging

Funding Type

PhD Type

The new EPSRC Centre for Doctoral Training (CDT) in Smart Medical Imaging at King's College London and Imperial College London continues the successful…
  EPSRC Centre for Doctoral Training (CDT) in Smart Medical Imaging

Funding Type

PhD Type

The new EPSRC Centre for Doctoral Training (CDT) in Smart Medical Imaging at King's College London and Imperial College London continues the successful…
  Open PhD positions - IMPRS for Heart and Lung Research

Funding Type

PhD Type

The International Max Planck Research School for Heart and Lung Research (IMPRS-HLR) offers up to ten positions to talented and enthusiastic students holding a relevant Master‘s degree.
  Our Mission: to Educate, Nurture and Discover for the benefit of Human Health

Funding Type

PhD Type

Our ultimate purpose is to work in service of patients. RCSI was founded by Royal Charter on 11th February 1784, to set and support professional standards for surgical training and practice in Ireland.
  PhD: Molecular mechanisms of chronic pain
  Dr P McHugh
Application Deadline: 31 March 2020

Funding Type

PhD Type

Chronic pain (CP) is a major cause of long term disability. Through a previous RNA seq analysis of human pain patients and animal models of neuropathic pain, we have identified several key pathways and molecules that could be important in disease process.
  Developing and applying computational methods to understand the genetics of ageing
  Dr JP de Magalhaes
Applications accepted all year round

Funding Type

PhD Type

Ageing is the chief biomedical challenge of the 21st century, yet it remains a major puzzle of biology. Although it is clear that the process of ageing has a strong genetic component, much work remains to elucidate how the genome regulates ageing.
  Targeting ageing: Genes and compounds with pro-longevity, health-preserving effects
  Dr JP de Magalhaes
Applications accepted all year round

Funding Type

PhD Type

Ageing is arguably the major biomedical challenge of the 21st century. In model organisms, the process of ageing can be manipulated by both genetic manipulations and dietary interventions.
  Live imaging of neural circuits mediating pain
  Dr A Nikolaev, Dr E Seward
Applications accepted all year round

Funding Type

PhD Type

The aim of this project is to characterize the neuronal circuitry involved in pain signaling in genetically modified zebrafish expressing fluorescent reporters of activity.
  Novel therapeutic approaches for the treatment of Duchenne muscular dystrophy.
  Prof S Winder
Applications accepted all year round

Funding Type

PhD Type

Duchenne muscular dystrophy (DMD) is caused by mutations in the DMD gene leading to loss of the cytoskeletal protein dystrophin.
  Characterisation of novel inhibitors of vascular injury due to inflammation
  Dr V Ralevic
Applications accepted all year round

Funding Type

PhD Type

Myeloperoxidase (MPO) is a haemoprotein that is highly expressed in neutrophils and is secreted during injury and inflammation to assist in host defence reactions by producing antimicrobial reactive oxygen species.
  Hydrogen sulphide as a treatment for respiratory disease.
  Dr R Roberts, Dr SPH Alexander
Applications accepted all year round

Funding Type

PhD Type

We have demonstrated that hydrogen sulphide (H2S) is synthesised within the airways in the lungs. H2S synthesis in the airways occurs through activation of the enzymes cystathionine  lyase, cystathionine β synthase, and mercaptopyruvate sulphurtransferase (MPST).
  The impact of pain on the aging nervous system
  Dr G Hathway
Applications accepted all year round

Funding Type

PhD Type

The way in which pain is detected and processed changes significantly over the life-course.
  Understanding structure and drug binding in the multidrug pump ABCG2
  Dr I Kerr, Dr R Layfield
Applications accepted all year round

Funding Type

PhD Type

ABCG2 is one of three human ATP binding cassette transporters that are functionally capable of exporting a diverse range of substrates from cells.
  Cardiac energetics and integrative physiology: Studying key components of the creatine kinase system to understand how they contribute to the pathophysiology of ischaemic heart disease and chronic heart failure.
  Prof C Lygate, Dr S Zervou
Application Deadline: 24 July 2020

Funding Type

PhD Type

Studying key components of the creatine kinase system to understand how they contribute to the pathophysiology of ischaemic heart disease and chronic heart failure.
  Immunity to Influenza and Ebola viruses
  Prof A Townsend
Application Deadline: 24 July 2020

Funding Type

PhD Type

This started with the investigation of T cell recognition of peptides derived from intracellular proteins of Influenza (Townsend et al 1986), that evolved into the development of a live attenuated, single cycle Influenza vaccine, based on these principles (Powell et al, 2012; Baz et al, 2015, Holzer 2018).
  Therapeutic targeting of chemokines in inflammation
  Prof S Bhattacharya
Application Deadline: 24 July 2020

Funding Type

PhD Type

Inflammation, driven by leucocytes, adversely affects organ function in diseases such as myocarditis, myocardial infarction, acute lung injury, sepsis and pancreatitis,.
  Immunity to Influenza and Ebola viruses
  Prof A Townsend
Application Deadline: 24 July 2020

Funding Type

PhD Type

This started with the investigation of T cell recognition of peptides derived from intracellular proteins of Influenza (Townsend et al 1986), that evolved into the development of a live attenuated, single cycle Influenza vaccine, based on these principles (Powell et al, 2012; Baz et al, 2015, Holzer 2018).
  Using CRISPR in iPS cells to modify platelet function
  Dr C.E. Hughes
Applications accepted all year round

Funding Type

PhD Type

"Platelets are the small cells in the blood whose job it is to prevent bleeding. Under normal conditions, when they encounter a damaged blood vessel they become activated and form a thrombus.
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