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We have 21 Pharmacology (chemical) PhD Projects, Programmes & Scholarships

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Pharmacology (chemical) PhD Projects, Programmes & Scholarships

We have 21 Pharmacology (chemical) PhD Projects, Programmes & Scholarships

Development of chemical tools and bioactive compounds to explore the importance of enzyme activity in cancer diseases

Diversity-oriented synthesis (DOS) is a modern chemical methodology, which aims to synthesise small molecules that cover new chemical space with the possibility of finding unexplored biological targets or pathways that may be important for disease progression. Read more

Control of Granulation Process using Seeded Granulation

  Research Group: Advanced Materials Engineering
Chemical and Pharmaceutical sector delivers a significant contribution to the world economy and the population as a whole. Read more

Using chemical-genetics to inhibit and characterise “undruggable” enzymes

The ability to inhibit kinases with small molecule drugs has transformed our understanding of signalling networks. It has allowed us to define the substrates and processes that each kinase controls, and to map how these enzymes cooperate within signalling pathways. Read more

Drug metabolism - prediction, detection, and isolation

Electrosynthesis (ES) is a green methodology for preparing and interpreting drug metabolites linked to toxicology. ES describes the synthesis of chemical compounds in an electrochemical cell. Read more

Novel strategy for treatment of chronic wounds via multi-functional liposomal nanocarriers

  Research Group: Medicines Development and Pharmaceutical Sciences
A confounding issue of non-healing skin wounds is the presence of pathogenic bacteria, that protect themselves from conventional antibiotic treatments by encasing themselves within protective shields (biofilms). Read more

MSc by Research: Glueing proteins together with small molecules

Recent advances from the Ciulli Lab and others have contributed to the establishment of a game-changing new modality of chemical intervention into biological system – one that moves beyond the state-of-the-art. Read more

Synthetic Protein-Transporters for Enhanced Transduction Activity

Intracellular protein delivery is key to probing important cellular processes and developing advanced biotherapeutics. However, protein trafficking into the cell, and more specifically to the cytosol remains a significant challenge. Read more

Development of Nanomaterials for Targeting the Bacteria–Host Interface in Cystic Fibrosis Airways

The attachment of Pseudomonas aeruginosa (PA) to the airway mucus in the lungs of people with cystic fibrosis (CF) represents an important step in airway colonization and the subsequent development of lung infection. Read more

Novel strategies for the diagnosis and treatment of snakebites

Snakebite envenomation (SBE), a high priority neglected tropical disease affects several million people worldwide resulting in as many as 150,000 deaths and around 500,000 permanent disabilities every year. Read more

Novel strategies and innovative technologies to produce amorphous solid dispersion

Poor drug solubility presents a major challenge in drug product development of oral solid dosage (OSD) forms. However, many new development compounds exhibit poor solubility and only a few of them reach market approval. Read more

Self funded MSc by Research or PhD in Biology: Ion channel signalling in cancer cells

Lead supervisor: Dr W Brackenbury. The student will be registered with the Department of Biology. Our cells constantly sense and transport ions present in their environment. Read more

Targeting Ras palmitoylation for the treatment of cancer

Lay summary. Proteins can be thought of as molecular machines that carry out work within cells. Protein activity can be regulated through the reversible attachment of certain chemical groups to specific amino acids within proteins. Read more

Development of antibody-drug conjugates (ADCs) for oncology indications

  Research Group: Institute of Cancer Therapeutics
A major challenge in cancer therapy is to develop therapeutic agents that selectively target tumour cells but are not harmful to normal tissue. Read more

Faculty of Pharmacy, Masaryk University

Discover the art of developing life-changing pharmaceuticals through our Medicinal Chemistry program. The aim of this programme is to prepare qualified experts who will work professionally in scientific activities in the field of development and analysis of drugs and its application to other scientific fields. Read more
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