University of Leeds Featured PhD Programmes
Engineering and Physical Sciences Research Council Featured PhD Programmes
University of Dundee Featured PhD Programmes
Sheffield Hallam University Featured PhD Programmes
University of Reading Featured PhD Programmes
"information" AND "studie…×
10 miles

Pharmacology / Toxicology (information studies) PhD Projects, Programs & Scholarships

We have 35 Pharmacology / Toxicology (information studies) PhD Projects, Programs & Scholarships

  • "information" AND "studies" ×
  • Pharmacology / Toxicology×
  • clear all
Order by 
Showing 1 to 30 of 35
  Inhibition of PRMT5 as a cancer therapy
  Dr K. Sheppard
Applications accepted all year round

Funding Type

PhD Type

Targeted therapy has had profound impact on outcomes for cancer patients.
  RNA Methylation in normal and malignant blood development
  Dr L. Kats
Applications accepted all year round

Funding Type

PhD Type

As is the case with DNA and histones, RNA can also be modified and indeed more than 100 chemical groups that decorate all four canonical RNA nucleotides have been described.
  Cutting off the fuel supply to calcium pumps in pancreatic cancer: a novel therapeutic strategy
  Dr J Bruce, Prof K Williams, Dr A P Gilmore
Applications accepted all year round

Funding Type

PhD Type

Background and Rationale. Pancreatic ductal adenocarcinoma (PDAC) has the poorest survival and limited treatment options. Therefore, the search for novel therapeutic targets and drugs designed to selectively kill PDAC cells must remain a central research strategy.
  GW4 BioMed MRC DTP PhD studentship: Advances in clinical management and laboratory detection of synthetic cannabinoids (“Spice”)
  Dr T P Freeman
Application Deadline: 25 November 2019

Funding Type

PhD Type

This project is one of a number that are in competition for funding from the ‘GW4 BioMed MRC Doctoral Training Partnership’ which is offering up to 18 studentships for entry in September 2020.
  Cardiac energetics and integrative physiology: Studying key components of the creatine kinase system to understand how they contribute to the pathophysiology of ischaemic heart disease and chronic heart failure.
  Prof C Lygate, Dr S Zervou
Application Deadline: 10 January 2020

Funding Type

PhD Type

Studying key components of the creatine kinase system to understand how they contribute to the pathophysiology of ischaemic heart disease and chronic heart failure.
  SWBio DTP PhD project: Role of microRNAs in regulating sex differences in stress responsive neurocircuitry across the lifespan
  Prof M Lindsay, Dr S J Bailey
Application Deadline: 2 December 2019

Funding Type

PhD Type

This project is one of a number that are in competition for funding from the South West Biosciences Doctoral Training Partnership (SWBio DTP).
  Metabolic Reprogramming in Liver Cancer: delineating the role of reactive oxygen species (ROS) in tumour development
  Prof T. Tiganis
Applications accepted all year round

Funding Type

PhD Type

The Tiganis Laboratory is seeking a highly enthusiastic student to conduct research in cancer metabolism and obesity-associated liver cancer.
  Quantitative Allele-Specific Proteomics in Drug Metabolism and Disposition
  Dr J Barber, Dr B Achour, Prof A Rostami
Applications accepted all year round

Funding Type

PhD Type

The effective dose of a drug is subject to considerable inter-individual variation because the enzymes that metabolise drugs and the proteins that transport them in and out of cells exist, in many cases, in different polymorphic forms and are expressed in varying concentration.
  MASTERS BY RESEARCH PROJECT: Can we improve patient outcomes by providing a more personalized approach to antiplatelet therapies?
  Dr S Mundell
Applications accepted all year round

Funding Type

PhD Type

Start 23 September 2019. This MSc by Research is a laboratory-based project which offers the exciting opportunity to spend 1 year in one of our State-of-the-Art laboratories (plus 1 year thesis writing) at the University of Bristol and experience life as a researcher.
  MRC DiMeN Doctoral Training Partnership: Understanding zinc-dependent regulation of TRPC5 channels and its role in diabetes
  Dr R.S. Bon, Dr S Muench, Dr P Sukumar
Application Deadline: 6 January 2020

Funding Type

PhD Type

TRPC5 ion channels are emerging drug targets, for example for CNS disorders, renal disease, cancer and cardiovascular disease (Cells 2018, 7, pii.
  Longitudinal trajectories of renal function, and dynamic prediction of progression to end-stage renal disease: a data-driven analysis and validation using regression and machine learning methods in a bi-national population-based cohort #NDORMS-2020/1
  Prof D Prieto-Alhambra, Dr V Strauss, Dr S Khalid, Dr D Robinson
Application Deadline: 10 January 2020

Funding Type

PhD Type

1. Prof Daniel Prieto-Alhambra. 2. Dr V Strauss. 3. Dr Sara Khalid. 4. Dr Danielle Robinson. 5. Dr Laurie Tomlinson. There is a scarcity of data on the natural history of chronic kidney disease (CKD) in the general population, and on markers of rapid progression to end-stage renal disease (ESRD).
  Hydrogen sulphide as a treatment for respiratory disease.
  Dr R Roberts, Dr SPH Alexander
Applications accepted all year round

Funding Type

PhD Type

We have demonstrated that hydrogen sulphide (H2S) is synthesised within the airways in the lungs. H2S synthesis in the airways occurs through activation of the enzymes cystathionine  lyase, cystathionine β synthase, and mercaptopyruvate sulphurtransferase (MPST).
  Understanding structure and drug binding in the multidrug pump ABCG2
  Dr I Kerr, Dr R Layfield
Applications accepted all year round

Funding Type

PhD Type

ABCG2 is one of three human ATP binding cassette transporters that are functionally capable of exporting a diverse range of substrates from cells.
  Inhibiting cell metabolism to enhance tumour cell death
  Dr C Bubici, Dr S Papa
Application Deadline: 31 January 2020

Funding Type

PhD Type

As you read this, millions of your cells from your body are dying. Do not panic – this is not bad news. Most of them are either superfluous or potentially harmful, so you are better off without them.
  Epigenetic mechanisms of behavioural, placental and cognitive impairment in a neurodevelopmental model for schizophrenia
  Dr R Hager, Prof J Neill, Dr J Glazier
Applications accepted all year round

Funding Type

PhD Type

A fundamental question in disease research is how stressors experienced during critical developmental periods influence the genesis or ‘programming’ of adult disease (Estes & McAllister 2016).
  Exploring the influence of proteogenomics in patients receiving biologic drugs for treatment of psoriatic arthritis
  Prof A Barton, Dr James Bluett, Dr N Nair
Applications accepted all year round

Funding Type

PhD Type

Background. Psoriatic arthritis (PsA) is an inflammatory arthritis, associated with the chronic skin condition psoriasis, which causes joint inflammation.
  Exploring the influence of treatment on CD4+ T-cell sub-populations in patients receiving biologic drugs for their inflammatory arthritis
  Prof A Barton, Dr D Plant, Dr S Viatte
Applications accepted all year round

Funding Type

PhD Type

Background. Tumour necrosis factor inhibitor (TNFi) therapy is ineffective for approximately 20% of rheumatoid arthritis (RA) patients and there is currently no way to predict which patients will not benefit.
  In vitro assessment of drug sequestration into lysosomes and in silico prediction of implications for drug disposition and therapeutic efficacy
  Dr A Galetin, Dr D Hallifax
Applications accepted all year round

Funding Type

PhD Type

Intracellular concentration of a drug is an important determinant of its efficacy, toxicity, and potential drug-drug interactions [1].
  Is there a switch between prostamides and prostaglandins in women with dysmenorrhoea and heavy menstrual bleeding?
  Prof K Marshall, Dr D Fischer, Prof A Nicolaou
Applications accepted all year round

Funding Type

PhD Type

Dysmenorrhoea, painful menstrual cramps, and heavy menstrual bleeding are common debilitating symptoms in women with or without an underlying pelvic pathology.
  Targeting ERK5 to enhance the DNA damage response to radiotherapy and chemotherapy
  Dr K Finegan, Dr C Demonacos
Applications accepted all year round

Funding Type

PhD Type

ERK5 is a signalling protein that enables cells to transduce extracellular signals into responses. It is expressed in all tissues and is up-regulated in tumours.
  GW4 BioMed MRC DTP PhD studentship: Structure of ART Toxins: understanding toxicity through host receptor interactions
  Prof R Mrsny, Dr G Masuyer
Application Deadline: 25 November 2019

Funding Type

PhD Type

This project is one of a number that are in competition for funding from the ‘GW4 BioMed MRC Doctoral Training Partnership’ which is offering up to 18 studentships for entry in September 2020.
  Open PhD positions - IMPRS for Heart and Lung Research

Funding Type

PhD Type

The International Max Planck Research School for Heart and Lung Research (IMPRS-HLR) offers up to ten positions to talented and enthusiastic students holding a relevant Master‘s degree.
  Big data approach to systematically investigate adverse drug reactions in older people
  Dr P Nishtala
Application Deadline: 8 December 2019

Funding Type

PhD Type

The University of Bath is inviting applications for a PhD position under the supervision of Dr Prasad Nishtala https://researchportal.bath.ac.uk/en/persons/prasad-nishtala and Professor Neil McHugh https://researchportal.bath.ac.uk/en/persons/neil-mchugh.
  Is disease risk conferred during childhood set in stone? Using genetics to understand how modifiable lifestyle changes can help prevent disease in later life
  Dr T Richardson
Application Deadline: 25 November 2019

Funding Type

PhD Type

The University of Bristol is offering a 3.5 year full time PhD in research around Population Health to start in 2019. This studentship is funded through GW4 BioMed MRC Doctoral Training Partnership.
  Platelets and hypoxia: how do varying oxygen concentrations affect platelet function and signalling?
  Dr M Arman
Applications accepted all year round

Funding Type

PhD Type

Platelets have key functions in regulating haemostasis and maintaining vascular integrity, which can cause cardiovascular disease if unbalanced.
  4 year DPhil (PhD) in Cardiovascular Science

Funding Type

PhD Type

Cardiovascular disease, including heart attacks and strokes, remains the leading cause of premature death and disability in Europe and the USA.
  Neuropeptide Research - PhD Opportunity at a World Class Institution
  Assoc Prof M Muttenthaler, Assoc Prof I Vetter
Applications accepted all year round

Funding Type

PhD Type

We are seeking talented and highly motivated PhD candidates for the following multidisciplinary project. Neuropeptides are key mediators in many biological functions and understanding their interaction with target proteins is fundamental to unravel the underlying mechanism of diseases.
  Characterisation of novel inhibitors of vascular injury due to inflammation
  Dr V Ralevic
Applications accepted all year round

Funding Type

PhD Type

Myeloperoxidase (MPO) is a haemoprotein that is highly expressed in neutrophils and is secreted during injury and inflammation to assist in host defence reactions by producing antimicrobial reactive oxygen species.
  The impact of pain on the aging nervous system
  Dr G Hathway
Applications accepted all year round

Funding Type

PhD Type

The way in which pain is detected and processed changes significantly over the life-course.
  Telomere length elongation following treatment with chemotherapeutic drugs. Aim: To investigate the mechanisms which leads to telomere length elongation after treatment with tricostatin A and azacytidine.
  Dr T Roberts
Applications accepted all year round

Funding Type

PhD Type

Telomeres are specialised structures, which are present at the ends of chromosomes and serve to protect the chromosome from degradation during cell division.
Show 10 15 30 per page


FindAPhD. Copyright 2005-2019
All rights reserved.