Imperial College London Featured PhD Programmes
Gdansk University of Technology Featured PhD Programmes
Solent University Featured PhD Programmes

Pharmacology (metabolism) PhD Projects, Programmes & Scholarships

We have 17 Pharmacology (metabolism) PhD Projects, Programmes & Scholarships

Discipline

Discipline

Medicine

Location

Location

All locations

Institution

Institution

All Institutions

PhD Type

PhD Type

All PhD Types

Funding

Funding

I am a self funded student


We have 17 Pharmacology (metabolism) PhD Projects, Programmes & Scholarships

PhD saved successfully

Polmorphisms in cytosolic drug metabolising enzymes: a combined proteomics and modelling approach to clinical impact

Cytosolic drug metabolising enzymes such as aldehyde oxidase play a pivotal role in metabolism of drugs. However, research into cytosolic enzymes has been relatively neglected in comparison with membrane bound enzymes such as cytochrome P450 (CYP) and uridine 5’-glucuronosyltransferases (UGTs). Read more

Determining brain glycosylation in ageing and Alzheimer’s disease

  Research Group: Pharmacology and Experimental Therapeutics
Increasing age is associated with lower levels of cognitive performance; concomitant with this is a decrease in brain glucose metabolism. Read more

Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

  Research Group: Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more

Cutting off the fuel supply to calcium pumps in pancreatic cancer: a novel therapeutic strategy

Background and Rationale. Pancreatic ductal adenocarcinoma (PDAC) has the poorest survival and limited treatment options. Therefore, the search for novel therapeutic targets and drugs designed to selectively kill PDAC cells must remain a central research strategy. Read more

Targeting the MAPK scaffold protein KSR1 for the treatment of prostate cancer

  Research Group: Institute of Cancer Therapeutics
Prostate cancer is one of the leading causes of male cancer deaths. It arises when individual cells escape their normal growth control mechanisms and proliferate in an uncontrolled fashion. Read more

Development of a Long Acting Parathyroid Hormone Fusion for the Treatment of Hypoparathyroidism

Parathyroid hormone (PTH) is an 84 aa peptide produced by the parathyroid glands and is responsible for calcium homeostasis. Hypoparathyroidism is a rare condition in which the parathyroid glands are either absent or damaged and therefore cannot produce any or sufficient amounts of parathyroid hormone. Read more

Understanding why cardiovascular dysfunction is one of the leading causes of mortality in patients with Non-Alcoholic Fatty Liver disease (NAFLD)

Background. Liver disease accounts for 3.5% of all global deaths/year (~2 million people) and is the third leading cause of premature death in the UK with some of the highest hospitalisations in the country seen in areas of socioeconomic deprivation. Read more

Development of antibody-drug conjugates (ADCs) for oncology indications

  Research Group: Institute of Cancer Therapeutics
A major challenge in cancer therapy is to develop therapeutic agents that selectively target tumour cells but are not harmful to normal tissue. Read more

Dietary intervention and efficacy in improving lipoedema symptoms among patients in the UK

About the Project. An ambitious and enthusiastic candidate is invited for one full-time PhD (self-funded or through an external fellow-ship application), starting any time between September 2021 and September 2022 (several intake times possible in this period). Read more

10+ fully funded PhD positions at the IMPRS for Molecular Organ Biology

 . PhD Studies in the Heart of Europe. The International Max Planck Research School for Molecular Organ Biology (IMPRS-MOB) offers fully funded positions to talented and enthusiastic students holding a relevant Master‘s degree. Read more

Filtering Results