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Pharmacy / Pharmaceutics (clinical chemistry) PhD Projects, Programs & Scholarships

We have 13 Pharmacy / Pharmaceutics (clinical chemistry) PhD Projects, Programs & Scholarships

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We have 13 Pharmacy / Pharmaceutics (clinical chemistry) PhD Projects, Programs & Scholarships

Non-Ubiquitin Mediated Targeted Degradation of Pathogenic Protein Aggregates

Start Date. 1st October 2021. Background. The ability to degrade targeted proteins is an exciting and emerging new field of drug discovery, with the first drug candidates undergoing clinical evaluation. Read more

Polmorphisms in cytosolic drug metabolising enzymes: a combined proteomics and modelling approach to clinical impact

Cytosolic drug metabolising enzymes such as aldehyde oxidase play a pivotal role in metabolism of drugs. However, research into cytosolic enzymes has been relatively neglected in comparison with membrane bound enzymes such as cytochrome P450 (CYP) and uridine 5’-glucuronosyltransferases (UGTs). Read more

Towards the development of a novel class of broad-spectrum anti-infective drugs

Through exceptionally strong research collaborations at the interface of chemistry, biology, and medicine, we have applied innovative thinking to the field of (Minor Groove Binders) MGBs to develop a novel platform for drug discovery with the potential to treat an impressive range of diseases, including bacterial, fungal, parasitic, and viral infections. Read more

Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

  Research Group: Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more

Novel design and formulation strategies to enhance drug delivery

The main research activities of my research group concern the improvement of traditional drug formulation and development of novel drug and formulation strategies to enhance bioavailability and patient acceptability. Read more

Nanotherapeutics for Improved Ocular Drug Delivery of Biologics

Eye diseases, such as age-related macular degeneration (AMD) are major causes of vision loss in the UK and worldwide. For example, approximately 600,000 people in the UK suffer from vision loss due to AMD. Read more

SMART Nanocarriers for Cancer

An important limitation in the treatment of cancer with therapeutics is the inability to achieve therapeutically effective local drug concentrations avoiding healthy tissue damage. Read more
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