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Pharmacy / Pharmaceutics (metabolism) PhD Projects, Programs & Scholarships

We have 9 Pharmacy / Pharmaceutics (metabolism) PhD Projects, Programs & Scholarships

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Showing 1 to 9 of 9
  Determining brain glycosylation in ageing and Alzheimer’s disease
  Research Group: Pharmacology and Experimental Therapeutics
  Dr R Williamson, Dr C Sutton
Applications accepted all year round

Funding Type

PhD Type

Increasing age is associated with lower levels of cognitive performance; concomitant with this is a decrease in brain glucose metabolism.
  Imaging cancer response and resistance to therapy using the chick CAM and isolated perfused tumour
  Dr T Witney, Dr R Southworth
Applications accepted all year round

Funding Type

PhD Type

Drug-resistance is a major obstacle for the effective treatment of patients with high grade metastatic cancer. Currently, there is no satisfactory way to identify patients that will respond and those that will fail standard-of-care therapy.
  Is there a switch between prostamides and prostaglandins in women with dysmenorrhoea and heavy menstrual bleeding?
  Prof K Marshall, Dr D Fischer, Prof A Nicolaou
Applications accepted all year round

Funding Type

PhD Type

Dysmenorrhoea, painful menstrual cramps, and heavy menstrual bleeding are common debilitating symptoms in women with or without an underlying pelvic pathology.
  Activity based proteomic probes for profiling CYP2W1 in cancer tissues
  Research Group: Institute of Cancer Therapeutics
  Dr C Sutton, Dr K Pors
Applications accepted all year round

Funding Type

PhD Type

Cytochromes P450 (CYPs) are a superfamily of mixed function oxidases of which CYP1-4 subfamily members are unique in their ability to oxidise drugs.
  Exploration of 5-fluorouracil resistance mechanisms in colorectal cancer using 5-FU-resistant xenograft models
  Research Group: Institute of Cancer Therapeutics
  Dr S Shnyder, Dr C Sutton
Applications accepted all year round

Funding Type

PhD Type

Despite therapeutic advances, colorectal cancer (CRC) still has a 45% mortality rate, and one of the major problems is the development of acquired resistance to treatment with anticancer drugs.
  Identifying glucose-dependent mechanisms underlying risk factors for Alzheimer’s disease
  Research Group: Pharmacology and Experimental Therapeutics
  Dr R Williamson, Dr S McLean
Applications accepted all year round

Funding Type

PhD Type

Several risk factors for Alzheimer’s disease including diabetes and midlife obesity are age-dependent and have an obvious metabolic component resulting in impaired glucose metabolism.
  Quantitative structure/skin-permeation relationships (QSPeRs); an investigation of the relevance of parameters determined with biomembrane-mimicking systems for the predictability of drug partitioning into skin
  Research Group: Medicines Development and Pharmaceutical Sciences
  Dr X Liu, Prof D J Tobin
Applications accepted all year round

Funding Type

PhD Type

The transdermal route has many advantages over other routes for the delivery of drugs with systemic activity. These include the ease of use (and withdrawal in the occurrence of side-effects), avoidance of first-pass metabolism, and improved patient compliance.
  Patterns and predictors of mortality during and after opiate substitution treatment in primary care
  Prof D Ashcroft, Prof R Webb, Dr M Carr, Prof T Millar
Application Deadline: 25 May 2019

Funding Type

PhD Type

Hypothesis. There may be varying individual-level clinical and sociodemographic factors, area-level socioeconomic patterns, and temporal trends in risks for natural and unnatural causes of death in patients receiving opiate substitution treatment across the UK that may provide important novel insights into prevention.
  Transdermal and Topical Drug Delivery: developing novel formulations to increase drug delivery into and through skin
  Prof A Williams
Applications accepted all year round

Funding Type

PhD Type

Human skin is a remarkable self-repairing barrier that controls the ingress of environmental contaminants and regulates water loss from the body.
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