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Pharmacy / Pharmaceutics (group) PhD Projects, Programs & Scholarships

We have 26 Pharmacy / Pharmaceutics (group) PhD Projects, Programs & Scholarships

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Showing 1 to 26 of 26
  EastBio Untangling the role of microglia in colonising brain tumours through targeted drug delivery
  Prof A N Hulme, Dr D Sieger, Prof V Brunton
Application Deadline: 5 January 2020

Funding Type

PhD Type

A PhD studentship is available in the group of Professor Alison Hulme (School of Chemistry, The University of Edinburgh; https://hulmegroup.wordpress.com/).
  Prevention of Gestational Diabetes in Obese Pregnant Women; Targeting Early Pregnancy Intervention to Women at Risk
  Dr S White, Dr A Flynn
Applications accepted all year round

Funding Type

PhD Type

Obesity in pregnancy increases the risk of gestational diabetes (GDM) and associated adverse outcomes. NICE guidelines recommend that all obese women have an oral glucose tolerance test at 24-28 weeks' gestation for detection of GDM.
  Developing the evidence for active intervention to support smoking cessation in cardiovascular disease
  Dr J Hartmann-Boyce, Dr N Lindson, Prof P Aveyard
Application Deadline: 10 January 2020

Funding Type

PhD Type

18% of people with incident heart disease smoke tobacco and less than half manage to stop. Clinicians intervene actively to support cessation for a small minority, when we know that continued smoking is a matter of addiction, not choice, for most of this group.
  Designing novel composite polysaccharide nanoparticles for combined diagnosis and treatment of cancers
  Dr E Barbu, Dr A Lalatsa
Applications accepted all year round

Funding Type

PhD Type

Cancer continues to impose a vast burden with regard to financial costs as well as human suffering but the progress in its treatment is hindered by the limited selectivity and significant side-effects that the current chemotherapy demonstrates, representing a major challenge for modern drug delivery.
  PhD in Chemical Biology -- Neuropeptide Research -- University of Vienna
  Prof M Muttenthaler
Applications accepted all year round

Funding Type

PhD Type

Neuropeptides are key mediators in many biological functions and understanding their interaction with target proteins is fundamental to unravel the underlying mechanism of diseases.
  EASTBIO: Understanding the pathogenesis of life-threatening Burkholderia cenocepacia infections using blocking antibodies and novel chemistry scaffolds to untangle complex aspects of AMR
  Prof A Porter, Dr S Palliyil, Prof M Jaspars
Application Deadline: 5 January 2020

Funding Type

PhD Type

Supervisors. Professor Andy Porter (University of Aberdeen). https://www.abdn.ac.uk/people/a.porter. Dr Soumya Palliyil (University of Aberdeen).
  MRC DiMeN Doctoral Training Partnership: Harnessing Autophagy for the Clinical benefit of Oropharyngeal Squamous Cell Carcinoma
  Prof P Lovat, Dr M Robinson
Application Deadline: 6 January 2020

Funding Type

PhD Type

Oropharyngeal squamous cell carcinoma (OPSCC) accounts for 97,000 deaths annually worldwide with an increasing incidence attributed to human papillomavirus (HPV).
  Direct Synthesis of Complex, Bioactive Molecules Through Control of Catalyst-Promoted Equilibria (ref: RDF20/APP/KNOWLES)
  Dr J Knowles
Application Deadline: 24 January 2020

Funding Type

PhD Type

Developing access to new areas of molecular space is a key objective for chemists,1 particularly to three-dimensional, sp3-rich compounds which show improved…
  MicroRNAs in the Pathogenesis Adverse Cardiomyocyte and Endothelial Cell Remodelling in Insulin Resistance
  Dr Q Su, Dr D Grieve
Application Deadline: 16 December 2019

Funding Type

PhD Type

Project details. Lipogenic diets-induced diabetes increases risk of cardiac stress and vascular dysfunction. Recent studies have established the pivotal role of non-coding microRNAs in the pathogenesis of cardiovascular disease (CVD).
  3D printing of drug delivery implants
  Dr P Boyd, Prof K Malcolm
Applications accepted all year round

Funding Type

PhD Type

Additive manufacturing (AM) or 3D printing (3DP) encompasses a wide range of. processes that create structures through deposition or binding of materials in successive.
  Dissecting novel mechanisms of cysteine protease biology in tumourigenesis
  Dr R Burden, Prof C Scott
Applications accepted all year round

Funding Type

PhD Type

Proteases are known for their role in facilitating tumour development, primarily through processes such as proliferation and invasion.
  Self-triggered smart biomaterials
  Dr C McCoy, Dr N Irwin
Applications accepted all year round

Funding Type

PhD Type

A major problem associated with medical devices is infection. With infection rates of approaching 100% in some devices, ways to prevent formation of bacterial biofilm on medical device surfaces are urgently required.
  Building scholarly communities of practice with an active and collaborative learning pedagogy (team-based learning (TBL))
  Research Group: Education Innovation Research and Development
  Dr G Quinn, Dr S Twedell
Applications accepted all year round

Funding Type

PhD Type

A ‘Community of Practice’ is a group of people who share a passion for something they do and learn how to do it better as they interact regularly.
  Design, synthesis and evaluation of protease-activated anti-cancer prodrugs
  Research Group: Institute of Cancer Therapeutics
  Dr R Falconer, Prof P Loadman
Applications accepted all year round

Funding Type

PhD Type

Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis.
  Formulation and evaluation of umbilical cord-derived mesenchymal stem cells exosomes and antioxidants, incorporated in nanoliposomes using microfluidics, for the treatment of solid tumours
  Research Group: Chemistry and Biosciences
  Dr M Najafzadeh, Prof D Anderson, Dr M Isreb
Applications accepted all year round

Funding Type

PhD Type

This project uses the Cord blood Stem Cells from healthy control and the white blood cells of blood cancer patients to investigate the efficacy and genotoxicity of different compounds in them by using various genetic endpoints.
  Informing Design of Novel Materials for Drug Pollution Remediation through Molecular Modelling
  Dr V Erastova
Applications accepted all year round

Funding Type

PhD Type

Summary. In this project, molecular modeling will be used to bring atomic-level understanding to the retention and release of contaminants by soils.
  Doctoral Candidate within the framework of the European project ULTIMATE - Investigation of functional molecules in ultra-high vacuum by scanning probe techniques
  Ms S Schmid
Application Deadline: 18 January 2020

Funding Type

PhD Type

The Single-Molecule Chemistry research group is looking for a Doctoral Candidate within the framework of the European project ULTIMATE.
  Re-purposing diabetes medicines to manage bleeding complications in myeloproliferative neoplasms.
  Prof Tim Palmer, Dr D Allsup
Application Deadline: 31 March 2020

Funding Type

PhD Type

Myeloproliferative neoplasms (MPNs) are a group of three related blood cancers in which the bone marrow overproduces one of the three cellular components of blood (erythrocytes, leukocytes and platelets).
  MRC DiMeN Doctoral Training Partnership: The in situ 3D molecular structure of Alzheimer’s disease-associated pathology by cryo-electron microscopy
  Dr R Frank, Prof S E Radford, Dr E W Hewitt
Application Deadline: 6 January 2020

Funding Type

PhD Type

Synapses are the microprocessors of the mind that encode and store memories. In Alzheimer’s disease (AD), synapses are damaged by the constituents of abnormal beta-amyloid plaques that accumulate in the brain.
  Prevalence, safety and efficacy of deprescribing cardio-protective medications in older adults
  Dr J Sheppard
Application Deadline: 10 January 2020

Funding Type

PhD Type

Cardiovascular disease is the leading cause of morbidity and mortality worldwide. Cardio-protective drugs such as statins, antihypertensives and antithrombotic medications have been shown to be effective at preventing cardiovascular disease in older high-risk patients.
  The molecular mechanisms underpinning individual variation in platelet function and their effect on the progression and treatment of cardiovascular disease.
  Dr CI Jones
Applications accepted all year round

Funding Type

PhD Type

Platelets are small blood cells that play a vital role in the chronic and acute progression of Cardiovascular Disease (CVD). Platelets respond to a range of agonists, which are released when blood vessels are damaged, by aggregating together to form thrombi.
  Design and synthesis of novel, targeted, anti-cancer agents
  Prof H Osborn, Dr F Greco
Applications accepted all year round

Funding Type

PhD Type

One of the major problems of cancer chemotherapy is that the drugs used have poor selectivities for cancer cells and cause damage to normal cells and organs.
  Developing novel formulations and materials for transmucosal drug delivery
  Prof V Khutoryanskiy
Applications accepted all year round

Funding Type

PhD Type

Mucosal routes of drug administration offer numerous advantages including ease of application, non-invasive nature and sometimes possibility of targeting particular organs.
  MRC DiMeN Doctoral Training Partnership: Activation of Aurora Kinase A by DNA damage – understanding the signalling pathway to improve radiotherapy response
  Dr H Bryant, Prof C Eyers, Prof P Eyers
Application Deadline: 6 January 2020

Funding Type

PhD Type

Radiation is a mainstay of cancer therapy, however radioresistance is a significant challenge in the treatment of locally advanced, recurrent and metastatic cancers.
  Discovery and characterisation of new antibiotics from uncultivated microbes.
  Dr J Owen
Applications accepted all year round

Funding Type

PhD Type

Recent developments in DNA sequencing technology have greatly enriched our understanding of the microbial world. By directly sequencing DNA extracted from communities of environmental microbes, we have been able to observe a hidden majority of microbial species that cannot be readily grown in the laboratory.
  Developing an Advanced Digital Twin for a Pharmaceutical Pilot Plant
  Dr PZ Moghadam, Dr P Soulatiantork, Prof M Zandi
Applications accepted all year round

Funding Type

PhD Type

The world-leading Diamond Pilot Plant Industry 4.0 Demonstrator (DiPP) already puts Sheffield and the UK at the centre stage of global research-led teaching facilities in process engineering and education.
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