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Pharmacy / Pharmaceutics (january) PhD Projects, Programs & Scholarships

We have 30 Pharmacy / Pharmaceutics (january) PhD Projects, Programs & Scholarships

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  Research Assistantship is Available for PhD in Pharmaceutical Sciences

Funding Type

PhD Type

The Graduate Program in Pharmaceutical Sciences at Texas Tech University Health Sciences Center (TTUHSC) School of Pharmacy in Amarillo, Texas is accepting applications from highly competent college graduates for admission into the Ph.D.
  Analysing the factors that regulate expression of blood-brain barrier drug transporter proteins
  Dr J L Penny, Dr C Demonacos
Applications accepted all year round

Funding Type

PhD Type

In order to treat diseases associated with the central nervous system (CNS), e.g. cancer, Parkinson’s disease, depression, it is essential for therapeutic drugs to be able to penetrate into the brain.
  It’s all in the Structure: Transforming drug design by bringing together molecular simulations and machine learning
  Dr G.C. Sosso
Applications accepted all year round

Funding Type

PhD Type

The solubility of pharmaceutical drugs determines to what extent they can be absorbed. Machine learning algorithms can predict the solubility of novel drugs without the need of actually synthetizing them - thus saving substantial time and money.
  Moving the tipping point: the decision to anticoagulate patients with atrial fibrillation
  Dr RW Wilkinson, Dr IS Siekmann, Prof G Lip, Prof P Lisboa
Applications accepted all year round

Funding Type

PhD Type

Atrial fibrillation (AF) is a heart condition that causes an irregular and often abnormally fast heart rate, and leads to a high risk of stroke and death.
  3D printing of drug delivery implants
  Dr P Boyd, Prof K Malcolm
Applications accepted all year round

Funding Type

PhD Type

Additive manufacturing (AM) or 3D printing (3DP) encompasses a wide range of. processes that create structures through deposition or binding of materials in successive.
  A randomised pilot study of a theory-based intervention to improve appropriate polypharmacy in older people in primary care (PolyPrime)
  Prof C Hughes, Dr H Barry
Applications accepted all year round

Funding Type

PhD Type

Historically, polypharmacy was viewed negatively (too many medicines), but the advent of multimorbidity and the plethora of treatment guidelines have led to prescribing of multiple medicines, particularly in the older population.
  Adaptation of Pseudomonas aeruginosa in people with bronchiectasis during chronic inhaled treatment
  Dr L Sherrard, Dr M Tunney
Applications accepted all year round

Funding Type

PhD Type

Some individuals with bronchiectasis have respiratory infections with Pseudomonas aeruginosa which may lead to a worse clinical trajectory.
  Antimicrobial prescribing in hospice and palliative care
  Dr C Parsons, Dr D Gilpin
Applications accepted all year round

Funding Type

PhD Type

Terminally ill patients are at high risk of infections and antimicrobial exposure near the end of life. However, the evidence-base to guide prescribers in the use of antibiotics for the treatment of infections in patients receiving hospice and palliative care is currently lacking.
  Clinical application of machine learning algorithms to determine appropriate antibiotic use in children with Gram-negative bacteria infections
  Dr Y Hsia, Prof C Hughes
Application Deadline: 29 February 2020

Funding Type

PhD Type

Digital health is a growing and productive field in recent years. The application of machine learning (ML) techniques in electronic healthcare databases has been successfully used for clinical diagnosis, outcome prediction, and disease progression.
  Computational prospecting of bacteriophage genomes and prophages for biotechnologically and pharmaceutically relevant enzymes
  Dr T Skvortsov
Applications accepted all year round

Funding Type

PhD Type

The number of bacteriophage genomes available in public databases keeps growing, but the problem of accurate prediction of functions of bacteriophage genes remains far from being solved.
  Computer Simulations of G protein-coupled Receptors
  Dr I Tikhonova
Applications accepted all year round

Funding Type

PhD Type

Many physiological processes are controlled through the activation of G protein-coupled receptors (GPCRs) by regulatory peptides, making peptide GPCRs particularly useful targets for major human diseases such as diabetes and CNS diseases.
  CONTRAsT - Cisplatin analogue gOld Nanoparticles for Tumour RAdiation Therapy
  Dr J Coulter
Application Deadline: 29 February 2020

Funding Type

PhD Type

This three year PhD position is an exciting industrial/academic collaboration which will afford the appointed student the opportunity to work closely with our partners Midatech Pharma.
  Deep learning analysis of large-scale sequence data in health and disease
  Dr B Devereux, Dr M Tunney
Application Deadline: 31 March 2020

Funding Type

PhD Type

As is the case in many other information processing domains, deep learning frameworks are emerging as powerful and highly effective tool in Bioinformatics and health analytics, including in the analysis of genetics, proteomics and clinical text data.
  Determining the microbiome of the homes of people with chronic respiratory diseases
  Dr D Gilpin, Dr D Downey
Applications accepted all year round

Funding Type

PhD Type

In recent years, our understanding of the microbial world in and around us has radically changed. The idea that we live with a complex and diverse community of microbes, has moved us away from a “hygiene hypothesis”, where having less bacteria was, to put it simply, better.
  Dissecting novel mechanisms of cysteine protease biology in tumourigenesis
  Dr R Burden, Prof C Scott
Applications accepted all year round

Funding Type

PhD Type

Proteases are known for their role in facilitating tumour development, primarily through processes such as proliferation and invasion.
  Enhancing Macrophage-Biofilm Interaction using Non-Thermal Plasma
  Prof B Gilmore, Dr P Flynn
Application Deadline: 29 February 2020

Funding Type

PhD Type

The ability to generate plasmas (quasi-neutral, wholly or partially ionised gases) at ambient or tissue tolerable temperatures has given rise to the nascent field of plasma medicine.
  Long-acting drug delivery from intravaginal rings for treatment of cervical intraepithelial neoplasia
  Prof K Malcolm, Dr P Boyd
Applications accepted all year round

Funding Type

PhD Type

Building on our world-renowned expertise in vaginal drug delivery, the aim of this project is to develop a long-acting vaginal ring device for treatment of cervical intraepithelial neoplasia.
  Microfabricated Engineered Systems for Sustained Ocular Drug Delivery
  Dr R Thakur, Dr D Lamprou
Applications accepted all year round

Funding Type

PhD Type

Retinal diseases that originate at the back of the eye, such as Age-related Macular Degeneration (AMD) and Diabetic Macular Edema (DME), represent the leading causes of vision loss in the Western world.
  Microfluidic Synthesis of Nanomedicines for the Delivery of Biologic Drugs
  Dr D Lamprou
Applications accepted all year round

Funding Type

PhD Type

Progress in drug design has led to the development of new molecules. However, the limited ability to selectively deliver these molecules at well-defined dosing regimens remains a significant challenge.
  Nanoparticle delivery of antibiotics for treatment of pulmonary infection
  Dr V Kett, Dr M Tunney
Applications accepted all year round

Funding Type

PhD Type

In respiratory diseases such as Cystic Fibrosis (CF) and COPD, the lungs are colonized by diverse polymicrobial bacterial communities.
  Novel drug delivery systems for Schizophrenia treatment
  Dr E Larraneta
Applications accepted all year round

Funding Type

PhD Type

This PhD project aims to develop, characterise and test a new type of implantable device to provide sustained antipsychotic drug delivery for schizophrenia treatment.
  Optimising pharmacological treatment of non-cognitive symptoms in people with dementia
  Dr H Barry, Prof C Hughes
Applications accepted all year round

Funding Type

PhD Type

Non-cognitive symptoms experienced by people with dementia may include agitation, aggression, distress, psychosis, anxiety and depression.
  Peptide hydrogels as a long-acting multipurpose drug delivery platform for combined contraception and HIV prevention
  Dr G Laverty, Prof K Malcolm
Applications accepted all year round

Funding Type

PhD Type

HIV/AIDS is the leading cause of death in women of reproductive age worldwide. HIV and unintended pregnancies are prevalent in developing nations due to the lack of effective female contraceptive choice.
  Peptide hydrogels as novel nanotherapeutic delivery agents enhancing the anti-tumour efficacy of radiotherapy
  Dr J Coulter, Dr G Laverty
Applications accepted all year round

Funding Type

PhD Type

There is a pressing clinical need for effective localised cancer treatments. Addressing this need we will develop a novel drug delivery system comprised of a nanoparticle/drug releasing hydrogel implant.
  Personalised Medicine for Breast and Ovarian Cancer
  Dr N Buckley, Dr H McCarthy
Applications accepted all year round

Funding Type

PhD Type

One in two people will develop cancer in their lifetime and it is a leading cause of death. While significant progress has been made in the treatment of some cancers, there still remain some forms of the disease with limited treatment options and poor outcome.
  Responsive hydrogel platforms towards the prevention of medical device-associated infections
  Dr N Irwin, Dr C McCoy
Applications accepted all year round

Funding Type

PhD Type

Catheter-associated urinary tract infections represent a high priority global healthcare challenge. We have recently identified a suite of non-antibiotic active agents with promising antibacterial and anti-encrustation activities.
  Self-triggered smart biomaterials
  Dr C McCoy, Dr N Irwin
Applications accepted all year round

Funding Type

PhD Type

A major problem associated with medical devices is infection. With infection rates of approaching 100% in some devices, ways to prevent formation of bacterial biofilm on medical device surfaces are urgently required.
  Surface-modified silicone elastomer for medical and drug delivery devices with reduced bacterial adherence and biofilm formation
  Dr L Carson, Prof K Malcolm
Applications accepted all year round

Funding Type

PhD Type

All implanted medical devices, including those fabricated from silicone elastomers, are susceptible colonisation with communities of microorganisms that colonise the surface of the device and rapidly establish biofilm populations.
  To develop an allosteric inhibitor of HDAC6 inhibition in cancer
  Dr F Furlong, Dr I Tikhonova
Applications accepted all year round

Funding Type

PhD Type

The HDAC6 protein is upregulated in cancer and associated with increased proliferation and metastasis. Several HDAC6 inhibitors have been developed and are in clinical trials.
  USP17 as a cancer therapeutic target
  Dr J Burrows
Applications accepted all year round

Funding Type

PhD Type

USP17 is over-expressed in a range of primary tumours including NSCLC, breast, colorectal, cervical, ovarian and osteosarcoma and its depletion has been shown to block the growth of cells from all these cancer types.
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