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We have 141 Pharmacy PhD Projects, Programmes & Scholarships

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Pharmacy PhD Projects, Programmes & Scholarships

We have 141 Pharmacy PhD Projects, Programmes & Scholarships

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Automated methodologies for analytes of biological and pharmaceutical interest based on luminiscence detection

Faculty of Pharmacy, Charles University, Department of Analytical Chemistry . Detection of fluorescence and chemiluminescence detection belong to the most sensitive techniques that can be used for analyte detection and quantification. Read more
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Green solvent extraction for pharmaceutical and contaminant analysis

Faculty of Pharmacy, Charles University, Department of Analytical Chemistry . During this thesis, the candidate should develop sample preparation methodologies using so-denoted tailored solvents that present alternatives to classical harmful extractants. Read more
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Development of electrophoretic methods for analysis of biologically active compounds

Faculty of Pharmacy, Charles University, Department of Analytical Chemistry . Due to its variety of separation mechanisms, capillary electrophoresis represents a complementary approach to liquid chromatography methods for the analysis of biologically active compounds in biological material. Read more

Peptide-mediated nanocarrier drug delivery for enhanced brain targeting and treatment of inflammation

This project involves the study of nanoparticles and drug delivery to the brain. The student would be required to make and characterise novel nanoparticles from special lipid molecules of various compositions more suitable for blood-brain barrier (BBB) targeting. Read more

How does the dynamic intra-membrane aggregation of phage lysis proteins kill bacterial pathogens?

This is an interdisciplinary project. It will provide a unique opportunity to obtain training in a wide range of interdisciplinary skills, including protein engineering techniques, protein purification, atomic force microscopy, neutron reflection and scattering as well as molecular dynamics simulations. Read more

Pharmacokinetics Guided Natural Products Exploration for Drug Discovery, Development, Delivery and Therapy

  Research Group: Institute of Cancer Therapeutics
Natural products have emerged as a key standard in novel and safe delivery of anticancer bioactive compounds. Apart from their ease of administration and delivery, natural/phytochemicals still face several hurdles, due to their physiochemical and pharmacokinetic properties. Read more

Enhancing treatment access to treatments for mental health and substance misuse in developing and emerging economies

Mental health problems and substance use disorder (SUD) are linked to poor health outcomes including adverse social outcomes such as homelessness and early mortality and are amongst growing global public health problem. Read more

Engineering extracellular vesicles/exosomes for the treatment of ocular disease

Extracellular vesicles, also referred to as exosomes, are membrane‐bound particles containing huge numbers of proteins as well as genetic material in the form of RNA (mRNA and miRNA). Read more
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Elucidating the role of lipids in fibrotic capsule formation at the surface of implanted medical devices.

Implanted medical devices are crucial in healthcare, valued at around £400 billion globally, however there is a high failure rate, often due to the foreign body reaction, where a fibrotic capsule forms around the implant with associated inflammation, loosening and infection. Read more

Inflammatory Arthritis in Childhood: Impact, Outcomes and Safety of Treatment

Juvenile Idiopathic Arthritis is the most common inflammatory arthritis of childhood. Although less common than arthritis in adults, a diagnosis of arthritis in a child can have lasting impacts on that child and their families through their entire lifespan. Read more

Therapeutic resolution of pulmonary arterial hypertension (PAH) by natural products

  Research Group: Pharmacology and Experimental Therapeutics
Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more

Therapeutic resolution of coronavirus (COVID-19) diseases by natural products

  Research Group: Pharmacology and Experimental Therapeutics
Coronavirus now labelled as Covid-19 has become a global pandemic affecting around 200 countries. Currently neither any cure nor any vaccine for Covid-19 has been established. Read more

Novel strategy for treatment of chronic wounds via multi-functional liposomal nanocarriers

  Research Group: Medicines Development and Pharmaceutical Sciences
A confounding issue of non-healing skin wounds is the presence of pathogenic bacteria, that protect themselves from conventional antibiotic treatments by encasing themselves within protective shields (biofilms). Read more

New Drugs for Brain Tumours: Prodrugs of Diazopropyne

  Research Group: Medicines Development and Pharmaceutical Sciences
The propargyl group, introduced to temozolomide-like drugs for brain tumours by our colleagues in Nottingham, shows considerable pre-clinical promise and… Read more

New Drugs for Brain Tumours: A Locoregional Implant Brain Tumours

  Research Group: Medicines Development and Pharmaceutical Sciences
Next-generation temozolomide derivatives for the treatment of high-grade glioma have been developed at the University of Bradford. Read more

Identifying cognitive and biochemical changes underlying lifestyle risk factors for dementia

  Research Group: Pharmacology and Experimental Therapeutics
Dementia describes a group of age-associated conditions of which cognitive decline is a major feature. Alzheimer’s disease (AD) is the most common cause of dementia and is characterised by the onset of a gradual cognitive decline. Read more

ERK5 MAPK signalling in Alzheimer’s disease

  Research Group: Pharmacology and Experimental Therapeutics
Neurodegenerative diseases have devastating effects on individuals’ lives and our society, with no effective treatments available. Read more

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