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We have 37 Queen’s University Belfast Pharmacy PhD Projects, Programmes & Scholarships

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Queen’s University Belfast Pharmacy PhD Projects, Programmes & Scholarships

We have 37 Queen’s University Belfast Pharmacy PhD Projects, Programmes & Scholarships

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High throughput exploration of the design space for antifungal nanocarrier development

Queen’s University Belfast School of Pharmacy
Fungal and bacterial infections contribute to over 7 million deaths yearly, affecting over 300 million people globally (GAFFI). Read more
 Supervisor: Dr J Tian
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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A systematic screening tool for nanocarrier design and efficient drug delivery against biological barriers.

Queen’s University Belfast School of Pharmacy
Encapsulation of APIs in a liposome can dramatically alter the distribution by controlling the release to normal tissue while facilitating the accumulation to the site of inflammation. Read more
 Supervisor: Dr J Tian
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Designing and evaluating novel nanotherapeutics to enhance the effectiveness of radiotherapy in the treatment of solid cancers.

Queen’s University Belfast School of Pharmacy
One in two cancer patients will receive radiotherapy as part of their treatment. For patients with a localised cancer diagnosis effective radiotherapy represents the best chance of a curative outcome, however, is not without risk. Read more
 Supervisor: Dr J Coulter
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Synthetic Protein-Transporters for Enhanced Transduction Activity

Queen’s University Belfast School of Pharmacy
Intracellular protein delivery is key to probing important cellular processes and developing advanced biotherapeutics. However, protein trafficking into the cell, and more specifically to the cytosol remains a significant challenge. Read more
 Supervisor: Dr S Carmali
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigation of novel protease-antiprotease imbalances associated with cystic fibrosis and the effect of CFTR correction.

Queen’s University Belfast School of Pharmacy
Cystic fibrosis (CF) is a progressive life-limiting airways disease that affects over 162,000 people worldwide. Read more
 Supervisor: Prof L Martin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Selective targeting of furin for the treatment of fibrotic lung disease.

Queen’s University Belfast School of Pharmacy
Furin, a proprotein convertase has been established as a therapeutic target across several disease areas to include chronic airways diseases and infectious disease, such as COVID-19 (reviewed in our recent publication, Douglas et al, 2023). Read more
 Supervisor: Prof L Martin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Developing biodegradable long acting drug delivery systems for the treatment of chronic conditions

Queen’s University Belfast School of Pharmacy
Non-adherence to treatment costs the NHS more than £500M each year. Adherence is especially important when treating patients with chronic conditions that require lifetime pharmacological treatment, such as schizophrenia, Parkinson’s disease, HIV and Alzheimer’s disease. Read more
 Supervisors: Dr E Larraneta, Prof R Donnelly
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Peptide-based nanoparticles for brain targeted gene delivery.

Queen’s University Belfast School of Pharmacy
Gene therapy has the potential to provide therapeutic benefit to millions of people with neurodegenerative diseases and cancer. Delivery into the brain is hampered by the blood-brain barrier (BBB), which limits the efficacy of both conventional and novel therapies at the target site. Read more
 Supervisors: Dr E McErlean, Prof H McCarthy
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Genetic Engineering of Immune Effector Cells for CAR therapies using a Peptide Technology

Queen’s University Belfast School of Pharmacy
Chimeric antigen receptor (CAR)-T therapies have demonstrated remarkable treatment outcomes and several CAR-T therapies now approved for treatment of haematological malignancies. Read more
 Supervisors: Dr E McErlean, Prof H McCarthy
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Characterising biofilm-forming microbes in endotracheal tubes to direct a new strategy for preventing ventilator-associated pneumonia in critically ill adults

Queen’s University Belfast School of Pharmacy
Endotracheal tubes (ETTs) are employed for invasive mechanical ventilation of critically ill patients with acute respiratory failure. Read more
 Supervisors: Dr L Sherrard, Dr M Wylie
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Developing novel therapeutic strategies to better treat Triple Negative Breast Cancer

Queen’s University Belfast School of Pharmacy
One in two people will develop cancer in their lifetime and it is a leading cause of death.  While significant progress has been made in the treatment of some cancers, there still remain some forms of the disease with limited treatment options and poor outcome. . Read more
 Supervisor: Dr N Buckley
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Self-regulating, self-cleaning biomaterials

Queen’s University Belfast School of Pharmacy
A major problem associated with medical devices is infection. With infection rates of approaching 100% in some devices, ways to prevent formation of bacterial biofilm on medical device surfaces are urgently required. Read more
 Supervisors: Prof C McCoy, Dr M Wylie
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Enzyme-responsive peptide hydrogels as in situ forming long-acting drug delivery implants

Queen’s University Belfast School of Pharmacy
One of the key issues in the treatment and prevention of disease is that patients struggle to adhere to the complex dosage regimens of therapies, which often require multiple dosing at very specific times each day. Read more
 Supervisor: Dr G Laverty
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Self-Navigating Nanocarriers for Intracellular Protein Delivery

Queen’s University Belfast School of Pharmacy
Protein-based therapeutics have shown remarkable success in modulating extracellular targets; however, effective intracellular delivery remains a key challenge in biotherapeutics. Read more
 Supervisor: Dr W Al-Jamal
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development of multifunctional biomaterials for urinary catheters to eradicate catheter-associated urinary tract infections

Queen’s University Belfast School of Pharmacy
Catheter-associated urinary tract infections (CAUTIs) are among the most common hospital-acquired infections worldwide threatening over 150 million people annually, imposing substantial burdens on the health system. Read more
 Supervisor: Dr SZ Zhang
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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