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Pharmacy (metabolism) PhD Projects, Programmes & Scholarships
We have 7 Pharmacy (metabolism) PhD Projects, Programmes & Scholarships
We have 7 Pharmacy (metabolism) PhD Projects, Programmes & Scholarships
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Polmorphisms in cytosolic drug metabolising enzymes: a combined proteomics and modelling approach to clinical impact
Cytosolic drug metabolising enzymes such as aldehyde oxidase play a pivotal role in metabolism of drugs. However, research into cytosolic enzymes has been relatively neglected in comparison with membrane bound enzymes such as cytochrome P450 (CYP) and uridine 5’-glucuronosyltransferases (UGTs). Read more
Determining brain glycosylation in ageing and Alzheimer’s disease
Research Group:
Pharmacology and Experimental Therapeutics
Increasing age is associated with lower levels of cognitive performance; concomitant with this is a decrease in brain glucose metabolism. Read more
Design, synthesis and evaluation of protease-activated anti-cancer prodrugs
Research Group:
Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more
Is there a switch between prostamides and prostaglandins in women with dysmenorrhoea and heavy menstrual bleeding?
Dysmenorrhoea, painful menstrual cramps, and heavy menstrual bleeding are common debilitating symptoms in women with or without an underlying pelvic pathology. Read more
Targeting the MAPK scaffold protein KSR1 for the treatment of prostate cancer
Research Group:
Institute of Cancer Therapeutics
Prostate cancer is one of the leading causes of male cancer deaths. It arises when individual cells escape their normal growth control mechanisms and proliferate in an uncontrolled fashion. Read more
Development of antibody-drug conjugates (ADCs) for oncology indications
Research Group:
Institute of Cancer Therapeutics
A major challenge in cancer therapy is to develop therapeutic agents that selectively target tumour cells but are not harmful to normal tissue. Read more
Dietary intervention and efficacy in improving lipoedema symptoms among patients in the UK
About the Project. An ambitious and enthusiastic candidate is invited for one full-time PhD (self-funded or through an external fellow-ship application), starting any time between September 2021 and September 2022 (several intake times possible in this period). Read more
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