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University of Reading, School of Pharmacy PhD Research Projects

We have 16 University of Reading, School of Pharmacy PhD Research Projects

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School of Pharmacy  University of Reading

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We have 16 University of Reading, School of Pharmacy PhD Research Projects

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Investigation of the critical roles of platelets at the interface between thrombosis and inflammation in order to develop improved therapeutic strategies for the treatment and/or prevention of cardiovascular/inflammatory diseases

Platelets (small circulating blood cells) are involved in blood clotting to prevent excessive bleeding, however, their inappropriate activation under pathological conditions leads to thrombosis resulting in major cardiovascular diseases such as heart attack and stroke. Read more

Understanding the biological role of the i-motif

The DNA i-motif is an important biological target which has recently been shown to form inside the nucleus of human cells. Current understanding of this structure is limited as it has received little research focus over the last 30 years, primarily because it was thought it couldn’t exist within biological environment. Read more

Developing novel formulations and materials for transmucosal drug delivery

Mucosal routes of drug administration offer numerous advantages including ease of application, non-invasive nature and sometimes possibility of targeting particular organs. Read more

Health behaviours in sport

Why do people behave the way they do? What impact can an individual’s behaviour have on their physical health? What are the unique challenges and opportunities experienced by people who participate in sport?. Read more

Biological role of neuropeptides and their receptors

Cell signalling is critical to the co-ordination and functioning of all cells. Cell signalling allows cells to co-ordinate activities within the intracellular environment as well as ensuring cells know how to correctly respond to other cells and to an ever-changing extracellular environment as well. Read more

Novel strategies for the diagnosis and treatment of snakebites

Snakebite envenomation (SBE), a high priority neglected tropical disease affects several million people worldwide resulting in as many as 150,000 deaths and around 500,000 permanent disabilities every year. Read more

TARGETING MITOPHAGY TO REDUCE CHEMOTHERAPY-INDUCED PAIN

"Background. Chemotherapy-induced peripheral neuropathy (CIPN) is the most commonly reported side effect of chemotherapeutic drugs, affecting quality of life in many cancer patients. Read more

Resilient dementia medication management in the home

Dementia medication management is a broad area. This project will focus specifically on medication management within people’s own homes, applying a Resilient Healthcare approach. Read more

Formulation of poorly-soluble drugs

Poorly water-soluble drugs is an important class of pharmaceutical compounds that are finding numerous applications for the therapy of different pathological conditions. Read more

Ion channel regulation in models of neurodegeneration

Ion channels are important regulators of cellular physiology. There is now growing awareness that these proteins are invovled in pathological states, with relation to neurodegeneration voltage-gated potassium and voltage-gated calicum channels have been implicated. Read more

Mechanisms of Cancer Stem Cell Survival, Metastasis Formation and Immune Evasion in Cancer

Recent research suggests that cancer cells within a tumour represent a highly heterogeneous cell population. In particular many tumours contain small percentage of cells that share several characteristics with stem cells. Read more

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