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We have 33 chromatin PhD Research Projects PhD Projects, Programmes & Scholarships

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chromatin PhD Research Projects PhD Projects, Programmes & Scholarships

We have 33 chromatin PhD Research Projects PhD Projects, Programmes & Scholarships

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Understanding control of genome folding by cohesin

University of Leicester Molecular and Cell Biology
Our basic goal is to understand how chromatin structure influences gene regulation. Chromatin is generally repressive in nature but its structure is manipulated by cells in a regulated way to determine which genes are potentially transcriptionally active and which genes remain repressed in a given cell type. Read more
 Supervisors: Prof D Panne, Dr T Schalch
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Structural insights into genome control by cohesin

University of Leicester Molecular and Cell Biology
Our basic goal is to understand how chromatin structure influences gene regulation. Chromatin is generally repressive in nature but its structure is manipulated by cells in a regulated way to determine which genes are potentially transcriptionally active and which genes remain repressed in a given cell type. Read more
 Supervisor: Prof D Panne
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Chromatin remodelling complexes in human brain development

King’s College London Faculty of Life Sciences & Medicine
Chromatin regulators are a group of proteins that control the way the rest of the genome is opened up and “read” by the cellular machinery, with fundamental roles in development and disease. Read more
 Supervisors: Dr CD Dias, Dr JA Atherton
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc By Research: How does SAF-A controls DNA replication and cell proliferation via open chromatin?

Aberdeen University School of Medicine, Medical Sciences & Nutrition
The MSc by Research programme at the University of Aberdeen is for students interested in a research-intensive master's degree. It is designed specifically to enhance your skills for a PhD or research career. Read more
 Supervisors: Dr S Hiraga, Prof A Donaldson
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Biological pathways supporting the formation and function of chromatin (Scholarship)

University of Liverpool Institute of Systems, Molecular and Integrative Biology
Every cell in our body contains the same DNA yet each cell expresses a different set of genes. These changes in gene expression are heavily influenced by histone proteins, their role in packaging DNA into chromatin and the “epigenetic” information they carry. Read more
 Supervisor: Dr CM Hammond
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Investigating the tumor suppressor functions of chromatin remodelling

University of Dundee School of Life Sciences
One of the unanticipated outcomes of population based genome sequencing has been the finding that genes involved in the regulation of many genes are mutated at high frequency in tissue specific cancers. Read more
 Supervisor: Prof T A Owen-hughes
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Chromatin regulation of oncogenic transcription and replication stress: mechanism and functional implications in acute myeloid leukemia

University of Liverpool Institute of Systems, Molecular and Integrative Biology
This project focuses on the molecular mechanisms promoting acute myeloid leukaemia (AML), a disease of great unmet need. AML is an aggressive blood and bone marrow cancer characterized by abnormal proliferation and differentiation of myeloid cells. Read more
 Supervisors: Dr M Papamichos Chronakis, Prof D MacEwan, Dr A Kanhere
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Unlocking the Secrets of Genome Regulation through cryo-EM

University of Leicester Molecular and Cell Biology
Are you an ambitious spirit, ready to make breakthrough discoveries at the frontier of epigenetics? Dive deep into the fascinating world of eukaryotic genomes with us! . Read more
 Supervisors: Dr T Schalch, Dr AC Chaplin
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Understanding gene regulation by HDAC1 complexes in development and cancer

University of Leicester Molecular and Cell Biology
Packaging DNA into nucleosomes helps protect the long fragile genomes of eukaryotic species. However, in doing so it becomes an ever-present physical barrier to the machinery required for its replication, repair and transcription. Read more
 Supervisor: Prof S Cowley
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Human Genetics, Genomics and Disease: Integrating fusion-proteins molecular signatures for advancing sarcoma diagnosis and therapy

University of Edinburgh College of Medicine and Veterinary Medicine
  Research Group: MRC Human Genetics Unit
Location. MRC Human Genetics Unit, University of Edinburgh, UK & Max Delbrück Center, Berlin, Germany. Supervisors. Dr Nezha Benabdallah, Dr Daria Bunina. Read more
 Supervisor: Dr NB Benabdallah
 19 May 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Investigating the role of dietary fructose in the development of early-onset colorectal cancer

University of Bristol Bristol Medical School
Project Background. This project will investigate the role of fructose in the development of early-onset colorectal cancer (EOCRC) in adults <50 years. Read more
 Supervisors: Dr E Vincent, Dr A Chambers, Dr R Richmond, Dr NM Murphy
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Mechanisms of control of 3D genome organisation

University of Leicester Molecular and Cell Biology
We have an exciting opportunity for exceptional PhD students to join us in a world-class research environment. We can offer a funded 3.5-year PhD scholarship open to UK and Overseas applicants. Read more
 Supervisor: Prof D Panne
 29 April 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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Self funded PhD in Biology: Structure and function of CIZ1

University of York Department of Biology
Lead supervisor: Prof Dawn Coverley. Co-supervisors: Prof Fred Antson. The student will be registered with the Department of Biology. Read more
 Supervisors: Prof D Coverley, Prof F Antson
 30 June 2024  PhD Research Project  Self-Funded PhD Students Only
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Unlocking the genetic potential of barley by modulating recombination

University of Leicester Department of Genetics and Genome Biology
Barley is a major worldwide crop used for malting and animal feed. However, breeding new varieties is constrained by the frequency of genetic crossovers (1-3 crossovers per chromosome pair) and their distribution (biased towards the chromosome ends) that underpin crop improvement1,2. Read more
 Supervisors: Dr J Higgins, Dr D Guttery
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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(MRC DTP CASE) Multiomic evaluation of differential drug response in metastatic breast cancers

The University of Manchester Faculty of Biology, Medicine and Health
Breast cancers are the most common cancers in women. Estrogen Receptor (ER) plays a major role in breast cancer growth. To stop the cancer from growing further, clinically successful ER-targeting therapies like Fulvestrant, etc were developed. Read more
 Supervisors: Dr S Nagarajan, Dr HH Harrison, Prof R Clarke, Dr I Iqbal
 13 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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