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We have 112 death PhD Research Projects

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We have 112 death PhD Research Projects

Identification of determinants of sudden cardiac death using population studies

Sudden cardiac death is a major cause of deaths from cardiovascular origin. Indeed, up to half of the deaths from cardiovascular diseases are caused by sudden cardiac death. Read more

Cancer: Inhibiting cell metabolism to enhance tumour cell death

All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. Read more

Metabolic reprogramming in cancer: starving tumors of essential nutrients to promote cell death

All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. Read more

Modulation of cell survival in cancer via the PERP route

Background. Programmed cell death (apoptosis) is a highly organised and tightly controlled physiological process used by all cells to control their survival or death in various conditions during their lifespan. Read more

Novel anti-pathogen regulatory mechanisms driven by Human Guanylate Binding Proteins

Human GBPs are a family of seven ~65kDa GTPases whose expression is upregulated by IFNg, for example during an infection. All mammalian GBPs contain a GTPase domain and a C-terminal helical region. Read more

Epigenetic regulation in heart failure and cardiac sudden death

A large proportion of heart failure patients die from cardiac sudden death (SCD), a direct result of lethal ventricular arrhythmias, which is the principal cause of mortality from heart disease worldwide and remains a major unresolved public health problem. Read more

Determining novel molecular regulators of necrosis controlling premature cell death

Necrosis, a form of premature cell death, is frequently caused by excessive insults such as trauma, infection and toxins. It has been implicated in many human diseases including cancer, neurodegenerative disorders and inflammatory diseases. Read more

Evaluating the impact of E-cigarettes on the innate immune response in chronic obstructive pulmonary disease

Research interests/description of main research theme. Cigarette smoking is the most common cause of chronic obstructive pulmonary disease (COPD), a progressively debilitating lung disease which is currently the fourth leading cause of death worldwide(1). Read more

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