inhibitor PhD Research Projects PhD Projects, Programmes & Scholarships

We have 30 inhibitor PhD Research Projects PhD Projects, Programmes & Scholarships

Identifying Mechanisms of Tyrosine Kinase Inhibitor Resistance in Breast/Cervical Cancer (with emphasis on FGFR)

Kingston University Faculty of Health, Science, Social Care and Education

FGF signalling is implicated in cancer (e.g., breast and cervical cancer) susceptibility and progression, suggesting that this powerful developmental pathway is co-opted by cancer cells. Read more

Supervisor: Dr A Chioni

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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The role of vitamin D3 in treating skin cancer and preventing drug resistance

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

During the last decade numerous studies have alluded to vitamin D. 3. playing a role in the prevention of cancer. Recent clinical trials looking at the potential role of vitamin D. Read more

Supervisors: Dr M Sutherland, Dr H Sheldrake, Dr S Kauser

Year round applications PhD Research Project Self-Funded PhD Students Only

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Preclinical testing of collagen synthesis inhibitors for fibrotic disease

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology

Fibrotic disease is characterised by an excessive accumulation of collagen within tissues, which then impedes tissue function. Organ fibrosis specifically kidney fibrosis, liver fibrosis, cardiac fibrosis and lung fibrosis have limited treatment options, pose a huge clinical burden and are life-limiting diseases. Read more

Supervisor: Dr EG Laird

Year round applications PhD Research Project Self-Funded PhD Students Only

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Urokinase-plasminogen activator as a target to block osteoarthritic cartilage destruction

University of Liverpool Institute of Life Course and Medical Sciences

Osteoarthritis (OA) is one of the major causes of disability globally, which is particularly significant in an ageing population. Read more

Supervisor: Dr D Wilkinson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Role of mechanical signals in a 3D human model of alveolar differentiation

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

Alveolar epithelial type I (AT1) and type II (AT2) cells are essential for normal lung function following birth. Abnormal differentiation of AT1 and AT2 cells during development results in pulmonary pathology with associated neonatal mortality and long-term morbidity. Read more

Supervisors: Dr S Loukogeorgakis, Dr F Michielin, Prof P De Coppi

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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MSc By Research: Can PTP1B inhibition rewire macrophage function to improve anti-tumour immunity in breast cancer treatment?

Aberdeen University School of Medicine, Medical Sciences & Nutrition

The MSc by Research programme at the University of Aberdeen is for students interested in a research-intensive master's degree. It is designed specifically to enhance your skills for a PhD or research career. Read more

Supervisors: Prof H Wilson, Prof M Delibegovic, Prof V Speirs

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigation of novel protease-antiprotease imbalances associated with cystic fibrosis and the effect of CFTR correction.

Queen’s University Belfast School of Pharmacy

Cystic fibrosis (CF) is a progressive life-limiting airways disease that affects over 162,000 people worldwide. Read more

Supervisor: Prof L Martin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Selective targeting of furin for the treatment of fibrotic lung disease.

Queen’s University Belfast School of Pharmacy

Furin, a proprotein convertase has been established as a therapeutic target across several disease areas to include chronic airways diseases and infectious disease, such as COVID-19 (reviewed in our recent publication, Douglas et al, 2023). Read more

Supervisor: Prof L Martin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Molecular Glues as Novel Tools for Tackling Big Challenges in Human Health

University of Leicester Department of Chemistry

Background. The need for new medicines is greater than ever because of an ageing population and the complex clinical challenges brought about by drug resistance and/or side effects. Read more

Supervisors: Dr RD Doveston, Prof S Macip

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Deciphering the effect of antibody-dependent cell phagocytosis and cytotoxicity (ADCC/ADCP) in the regulation of cross-presentation and antigen spreading in liver cancer.

University of Oxford Nuffield Department of Medicine

Primary liver cancers (hepatocellular carcinoma [HCC] and intrahepatic cholangiocarcinoma) are the fourth leading cause of malignancy-related mortality worldwide. Read more

Supervisors: Dr F Galvez-Cancino, Prof I Melero Bermejo

6 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Exploring the multi-organ benefits of Rapamune in relation to ageing physiology

University of Nottingham School of Life Sciences

PhD Description. Drug repurposing is an emerging avenue of research in the field of Geroscience; a field whose stated aim is to “accelerate research into the basic mechanisms driving ageing which could lead to improved clinical interventions”. Read more

Supervisor: Prof P Atherton

22 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Gaining mechanistic insights into Atrial Fibrillation: Bench to bedside approaches

University of Liverpool Department of Pharmacology and Therapeutics

Atrial fibrillation (AF) is a common arrhythmia with symptoms like irregular heart rate, palpitations, shortness of breath, tiredness, and dizziness. Read more

Supervisor: Dr RB Burton

1 July 2024 PhD Research Project Self-Funded PhD Students Only

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BARIToNE: Using Next Generation Nitrogen Sources For Producing Spring Malting Barley and its Impact on Yield and Grain Malt Quality (Project code 24B)

University of Nottingham School of Life Sciences

Supervisors. Lead supervisor. Dr John Foulkes, University of Nottingham. Second supervisor. Dr Guillermina Mendiondo, University of Nottingham. Read more

Supervisors: Dr M J Foulkes, Dr G Mendiondo, Mr S Smith

31 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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The role of eIF2Bα in the response to Integrated Stress Response (ISR) modulation in cancer

Sheffield Hallam University Biomolecular Sciences Research Centre

The Industry and Innovation Research Institute (I2Ri) draws on talents, expertise and facilities across Sheffield Hallam University. Read more

Supervisors: Dr E Allen, Dr SC Campbell

10 May 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Use of a novel conjugation approach to generate a long-acting growth hormone receptor antagonist

University of Auckland Liggins Institute

Targeting the growth hormone (GH) signalling pathway could be an effective therapeutic approach for certain types of cancer. However, a lack of access to therapeutics that target GH or the GH receptor has hindered preclinical studies in this field. Read more

Supervisors: Dr Y Wang, Dr J Perry

30 August 2024 PhD Research Project Self-Funded PhD Students Only

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We have 30 inhibitor PhD Research Projects PhD Projects, Programmes & Scholarships

inhibitor PhD Research Projects PhD Projects, Programmes & Scholarships

We have 30 inhibitor PhD Research Projects PhD Projects, Programmes & Scholarships

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