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We have 23 zebrafish PhD Research Projects PhD Projects, Programmes & Scholarships

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zebrafish PhD Research Projects PhD Projects, Programmes & Scholarships

We have 23 zebrafish PhD Research Projects PhD Projects, Programmes & Scholarships

Exploring a novel neurodevelopmental disease gene using a zebrafish model

The Rare Disorder Genetics / Bicknell lab is interested in characterising novel genetic syndromes, with three core motivations. -the difference we can make to families with rare disorders, through providing them with more information. Read more

Understanding the role of pigmentation in retinal and vision development

Establishing structure-function correlations in vision development  . The aim of this project is to develop methods to study the relationship between pigmentation and vision development in humans and zebrafish.  . Read more

Exploring Molecular Pathways for Improved Neural Regeneration in Spinal Cord Injury

In the UK, 50,000 people currently live with spinal cord injury (SCI), and an additional 2,500 new cases are reported annually. SCI results in a permanent loss of sensation and movement, serving as a primary cause of paralysis for which effective treatments are currently unavailable. Read more

Understanding Spinal Cord Regeneration: The role of dynamic gene expression

Spinal cord injury(SCI) paralysis is a devastating disease that affects at least 2500 people per year in the UK. It carries substantial individual and societal costs with most SCI sufferers experiencing chronic pain. Read more

Investigating monogenic disorders of the protein synthesis machinery

Translation of mRNA into proteins is a critical cellular biological process. We recently described a novel human disorder, now called Faundes-Banka Syndrome (FABAS), caused by heterozygous variants in EIF5A1 that encodes a translation factor. Read more

The analysis of HIF function in DNA repair and genome stability

DNA damage is a factor that underlies many human diseases. Such damage results in mutations, and if such genetic alterations occur in tumour suppressor or proto-oncogenes it can lead to cancer. Read more

Morphology, motion, and mechanics of vertebral joints in fish

We depend on healthy joints to stay active, independent and productive. Disorders of the joints of our spine (intervertebral joints) are particularly disruptive, with back pain and disorders impacting millions of people. Read more

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