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action research PhD Research Projects PhD Projects, Programmes & Scholarships

We have 195 action research PhD Research Projects PhD Projects, Programmes & Scholarships

Exploring and understanding inclusivity of LGBTQIA+ recreational athletes in the UK

Researchers, practitioners, and policy makers have shown that physical, mental, and social health research disparities exist between lesbian, gay, bisexual, transgender, queer, intersex, asexual (LGBTQIA+) populations and others. Read more

Molecular mechanisms of pacemaker (sinus node) dysfunction in ageing, heart failure and athletes

  Research Group: Chemistry and Biosciences
The heart’s pacemaker, the sinus node, initiates the action potential that causes the heart to beat, and the atrioventricular node conducts the action potential from the atria to the ventricles, the pumping chambers of the heart. Read more

Living with allergy during the transition to secondary school

Allergy, the immune system’s hypersensitive reaction to typically harmless substances, can be severe and lead to a potentially life-threatening reaction or anaphylaxis (Turner et al, 2019). Read more

Targeting the MAPK scaffold protein KSR1 for the treatment of prostate cancer

  Research Group: Institute of Cancer Therapeutics
Prostate cancer is one of the leading causes of male cancer deaths. It arises when individual cells escape their normal growth control mechanisms and proliferate in an uncontrolled fashion. Read more

Pharmacokinetics Guided Natural Products Exploration for Drug Discovery, Development, Delivery and Therapy

  Research Group: Institute of Cancer Therapeutics
Natural products have emerged as a key standard in novel and safe delivery of anticancer bioactive compounds. Apart from their ease of administration and delivery, natural/phytochemicals still face several hurdles, due to their physiochemical and pharmacokinetic properties. Read more

Computer Vision with Deep Learning for Human Data Modelling

This project is focused on learning algorithms to model human data such as human images/video, 3D skeletal motion, 3D body/facial surfaces for computer vision tasks such as recognition, prediction and reconstruction. Read more

The role of vitamin D3 in treating skin cancer and preventing drug resistance

  Research Group: Chemistry and Biosciences
During the last decade numerous studies have alluded to vitamin D. 3. playing a role in the prevention of cancer. Recent clinical trials looking at the potential role of vitamin D. Read more

Mechanisms underlying the effects of activated protein C (APC) in cardiac muscle

  Research Group: Chemistry and Biosciences
APC is an anticoagulant enzyme that also exerts antithrombotic, anti-inflammatory, antiapoptotic and a variety of other cytoprotective effects in different tissues, where the mechanism of action is thought to involve the endothelial protein C receptor (EPCR) and a protease activated receptor (PAR). Read more

Characterisation of adrenoceptor and muscarinic receptor subtypes coupled to potassium channels in chondrocytes from bovine cartilage

  Research Group: Chemistry and Biosciences
Several outward potassium currents have been identified in bovine chondrocytes (review Mobasheri et al. 2012). These include ATP-sensitive and a Calcium-activated potassium currents (Sanches & Lopez-Zapata, 2011). Read more

Microbiology of Hip Arthroplasty Cements

  Research Group: Centre for Skin Sciences
Replacement hip and knee arthroplasties are common surgeries, with 31,000 hip and 90,000 knee replacements performed in England in 2020-21. Read more

Language Model-Grounded User Simulation for Personalised Conversational Systems

This PhD project aims to advance the development of personalised conversational systems by leveraging user simulation, an area of research supported by recent advancements in large language models known for their strong capability in natural language understanding and generation. Read more

New Drugs for Brain Tumours: Prodrugs of Diazopropyne

  Research Group: Medicines Development and Pharmaceutical Sciences
The propargyl group, introduced to temozolomide-like drugs for brain tumours by our colleagues in Nottingham, shows considerable pre-clinical promise and… Read more

New Drugs for Brain Tumours: A Locoregional Implant Brain Tumours

  Research Group: Medicines Development and Pharmaceutical Sciences
Next-generation temozolomide derivatives for the treatment of high-grade glioma have been developed at the University of Bradford. Read more

Neuronal control of appetite: investigating the role of the extracellular matrix in controlling neuronal activity in the hypothalamus

  Research Group: Chemistry and Biosciences
Appetite regulation is complex, and its dysregulation has serious implications for health, being observed in multiple conditions e.g., obesity, anorexia, and type 2 diabetes. Read more

Investigation of the extracellular matrix as a regulator of Parkinson’s progression

  Research Group: Chemistry and Biosciences
Parkinson’s is the 2nd most common neurodegenerative disease, affecting around 1 in 20 people aged over 65. In the UK, the number of affected people is set to rise by 50% over the next 50 years due to ageing populations. Read more
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The development of a risk assessment tool for under 18-year-olds who display harmful sexual behaviour, both offline and online

Around a third of sexual abuse is perpetrated by children and young people. However, current assessment tools have primarily been informed by what is known about the treatment needs of adult sexual offenders, and there is a lack of research involving young people and their families. Read more

MSc by Research: How are SUMO substrates selected for modification ?

SUMO has diverse roles in cellular physiology that in most cases are mediated by its ability to interact non-covalently with hydrophobic patches of low sequence complexity known as SUMO Interaction Motifs (SIMs). Read more

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