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Biochemistry PhD Research Projects

We have 687 Biochemistry PhD Research Projects

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We have 687 Biochemistry PhD Research Projects

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Chemo-enzymatic Synthesis and Potential Applications of Novel antimicrobial peptides

Antimicrobial resistance (AMR) is rising to dangerously high levels in all parts of the world. In Europe alone, drug-resistant bacteria are estimated to cause 25,000 deaths annually and cost more than US$1.5 billion every year in healthcare expenses and productivity losses. Read more

EASTBIO CASE Molecular engineering of the ubiquitin-proteasome system: A new approach to pathogen resistance in plants

  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
Barley (Hordeum vulgare) is the fourth most important crop worldwide and second in the UK. Diseases, including those caused by the brown rust pathogen, Puccinia hordei, cause barley yield losses of up to 40%. Read more

EASTBIO Ubiquitin dynamics during host-pathogen interaction

  Research Group: Institute of Immunology & Infection Research
Protein ubiquitination is a key regulatory process that controls many aspects of eukaryotic life. Both free living and pathogenic organisms employ ubiquitination mediated protein networks to adapt to their environment. Read more

EASTBIO Bioengineering novel platforms for one-pot plastic upcycling

  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
Background. Plastic pollution is a major environmental threat and sequesters carbon-rich materials derived from finite, petrochemical resources. Read more

EASTBIO The role of host membrane protein interactions in herpesvirus nuclear egress and SARS-CoV-2 double membrane vesicle formation

  Research Group: Institute of Cell Biology
    Viruses have many critical interactions with host cell membranes that mostly take advantage of host cell proteins. The Schirmer and Graham labs have 2 lines of investigation involving virus interactions with host cell membrane proteins that could be individually or jointly carried further in this PhD project. . Read more

EASTBIO Dynamics of mitochondrial genome complexity in trypanosomes

  Research Group: Institute of Immunology & Infection Research
Human and livestock diseases caused by trypanosomatid parasites threaten health and livelihood of millions of people in Africa, South America and Asia. Read more

PhD student position available in macronutrition and signaling regulated RNA metabolism

PhD student position available in macronutrition and signaling  regulated RNA metabolism. The main research focus of our laboratory is to understand the participation of RNA processing in the regulation of energy metabolism in the context of obesity and diabetes. . Read more

EASTBIO Understanding barley-Puccinia interaction: the interaction between pathogen effectors and the host immune system

  Research Group: Institute of Molecular Plant Sciences
Barley (Hordeum vulgare) is the fourth most important arable crop worldwide and second in the UK. Diseases, including those caused by the brown rust pathogen Puccinia hordei, cause barley yield losses of up to 40%. Read more

EASTBIO Phospho-regulation of meiosis

  Research Group: Institute of Cell Biology
Genes must be passed on accurately from cell to cell and from parents to children. Failure to do so can be a cause or contributing factor in human illnesses, such as cancer or reproductive problems/congenital conditions. Read more

EASTBIO Do circadian rhythms in ion concentrations drive cellular metabolic rhythms?

  Research Group: Institute of Molecular Plant Sciences
In the living cell, virtually nothing stays the same over the day/night cycle. Endogenous ~24h rhythms are driven by a biological timekeeping system, the circadian clock, that dynamically regulates nearly all biological processes to match Earth's environmental cycle. Read more

EASTBIO: How cells prevent errors in chromosome inheritance during cell division

Human cells store their genetic information in 46 chromosomes. To maintain this vital genetic information, a complete set of chromosomes must be inherited precisely by each daughter cell after cell division. Read more

EASTBIO: Your Best Face Forward - how cereals regulate their epidermal surfaces

Plants living on land face brutal conditions with threats from pests, dehydration and temperature extremes. To survive and thrive on land, plants evolved a specialised surface, sealed by a waxy ‘cuticle’ and distinctive epidermal cells such as gas pores and defensive barbs. Read more

EASTBIO Bone biomineralisation

This project will investigate the fundamental mechanisms which regulate bone mineralisation through extracellular vesicles. A deeper understanding of this process will expose new therapeutic targets for the treatment of bone disorders. Read more

EASTBIO Expanding the chemistry of non-heme enzymes

Chemical synthesis is widely viewed as being unsustainable. Whilst this is an oversimplification, in many cases chemical production still relies on petrochemicals, rare metals and high energy consumption to make the products we need for modern life. Read more

EASTBIO New chemical tools to understand and exploit tubulin diversity

Microtubules are long polymers important for cell division, intracellular transport and polarity. Many isotypes of microtubules co-exist in human cells and levels of expression vary with the cell type. Read more

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