Norwich Research Park Featured PhD Programmes
University of Oxford Featured PhD Programmes
Norwich Research Park Featured PhD Programmes

Biochemistry PhD Research Projects

We have 745 Biochemistry PhD Research Projects

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We have 745 Biochemistry PhD Research Projects

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Probing a novel allosteric binding site in Mycobacterium DNA gyrase to tackle TB and antimicrobial resistance

Human pathogenic bacteria, e.g. Mycobacterium tuberculosis (TB), show increasing resistance to current antibiotics. Antimicrobial resistance (AMR) is probably the biggest current threat to human health; it is estimated that 10 million people per year could die because of AMR by 2050. Read more

Exploring the health benefits of greater fitness - The health benefits of greater fitness across the life course

About the research project -. https://www.utas.edu.au/our-research/research-degrees/available-projects/health-and-medicine/area/menzies-institute-of-medical-research/fitness,-cardiovascular-risk,-and-exercise-blood-pressure. Read more

EASTBIO Biocatalyst cascades for drug synthesis

Project Details. Natural and engineered biocatalysts are already having impact in the manufacture of high value pharmaceuticals by catalysing the conversion of functional groups in high yield. Read more

Navigating through sequence space to understand Alpha-Synuclein Aggretion

The aggregation of the 140 residue protein a-synuclein into amyloid fibres is associated with neurodegenerative diseases known as synucleinopathies including Parkinson’s disease (the second most common neurodegenerative disease worldwide). Read more

Evolution and engineering of non-ribosomal peptide synthetases (WILKINSON_J22DTP1)

The discovery & development of penicillin sparked ‘The Golden Age of Antibiotics’ which spanned the 1940’s to 1960’s when most major classes of antibiotics were discovered. Read more

Understanding Streptomyces cell division to improve antibiotic production (SCHLIMPERT_J22DTP)

Every cell must divide to grow and to propagate. While most bacteria simply split in half, the decision when and where to divide is more complex in multicellular bacteria like the antibiotic producing soil bacteria Streptomyces. Read more

Deciphering the in vivo RNA structure code in regulating protein translation in plants (DING_J22DTP2)

Codon optimisation is a common method in synthetic biology to achieve high levels of protein expression. It relies on the creation of so-called “silent” or synonymous mutations within a coding sequence, such that the DNA/RNA sequence is altered but the resulting amino acid sequence remains unchanged. Read more

Investigating how Plants use RNA to Cope with Stress (DING_J22DTP1)

The diversity of RNA structure is wide and varied, from hairpins and bulges through to triplex and quadruplexes. These structures are able to control numerous biological functions from sensing of messenger compounds to dictating whether genes are switched on or off. Read more

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