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Biochemistry PhD Research Projects

We have 745 Biochemistry PhD Research Projects

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We have 745 Biochemistry PhD Research Projects

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Control of Cell Polarity in Plants (COEN_J22DTP)

Cell polarity is fundamental for growth and division in plants. The BASL protein is localised to one end of stomatal precursors and plays a critical role in asymmetric division and stomatal spacing. Read more

Engineering enhanced vitamin synthesis in bacteria (WARRENM_Q22CASE)

This project aims to apply synthetic biology and metabolic engineering strategies to one of the most complex biochemical pathways found in nature in order to address a current need for a cheaper and more reliable source of vitamin B12, the so-called anti-pernicious anaemia factor. Read more

Are bacteria building toxic biofilms in your gut? (NARBAD_Q22DTP2)

Think of a corroded pipe. Now think of an inflamed gut. These conditions may be caused by similar bacteria. Sulphate reducing bacteria (SRB) are anaerobic bacteria, common in the environment and the gastrointestinal tract. Read more

Can we use bacteriocins to improve gut health? (NARBAD_Q22DTP1)

Many bacteria produce antimicrobial compounds to help them compete in mixed communities. Antimicrobial peptides called bacteriocins from food and dairy strains have already been exploited successfully to prevent food poisoning or mastitis. Read more

*Eastbio*: Serum albumin glycation and its impact on Zn2+-dependent haemostasis and insulin dynamics

Zinc is an essential micronutrient in mammals, vital to virtually all physiological pathways and processes. High nanomolar concentrations of free zinc ions (Zn2+) are cytotoxic; therefore, extracellular zinc is usually well-buffered. Read more

Chemo-enzymatic Synthesis and Potential Applications of Novel antimicrobial peptides

Antimicrobial resistance (AMR) is rising to dangerously high levels in all parts of the world. In Europe alone, drug-resistant bacteria are estimated to cause 25,000 deaths annually and cost more than US$1.5 billion every year in healthcare expenses and productivity losses. Read more

EASTBIO CASE Molecular engineering of the ubiquitin-proteasome system: A new approach to pathogen resistance in plants

  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
Barley (Hordeum vulgare) is the fourth most important crop worldwide and second in the UK. Diseases, including those caused by the brown rust pathogen, Puccinia hordei, cause barley yield losses of up to 40%. Read more

EASTBIO Ubiquitin dynamics during host-pathogen interaction

  Research Group: Institute of Immunology & Infection Research
Protein ubiquitination is a key regulatory process that controls many aspects of eukaryotic life. Both free living and pathogenic organisms employ ubiquitination mediated protein networks to adapt to their environment. Read more

EASTBIO Bioengineering novel platforms for one-pot plastic upcycling

  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
Background. Plastic pollution is a major environmental threat and sequesters carbon-rich materials derived from finite, petrochemical resources. Read more

EASTBIO The role of host membrane protein interactions in herpesvirus nuclear egress and SARS-CoV-2 double membrane vesicle formation

  Research Group: Institute of Cell Biology
    Viruses have many critical interactions with host cell membranes that mostly take advantage of host cell proteins. The Schirmer and Graham labs have 2 lines of investigation involving virus interactions with host cell membrane proteins that could be individually or jointly carried further in this PhD project. . Read more

EASTBIO Dynamics of mitochondrial genome complexity in trypanosomes

  Research Group: Institute of Immunology & Infection Research
Human and livestock diseases caused by trypanosomatid parasites threaten health and livelihood of millions of people in Africa, South America and Asia. Read more

PhD student position available in macronutrition and signaling regulated RNA metabolism

PhD student position available in macronutrition and signaling  regulated RNA metabolism. The main research focus of our laboratory is to understand the participation of RNA processing in the regulation of energy metabolism in the context of obesity and diabetes. . Read more

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