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Bioinformatics PhD Research Projects

We have 13 Bioinformatics PhD Research Projects

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Maths & Computing

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PhD Research Projects

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I am a non-European student


We have 13 Bioinformatics PhD Research Projects

Successfully added to shortlist

Genome-wide translational responses to stress

We are interested in gene regulation in responses to stress, using both simple model organisms, human and plant pathogens. Cells respond to stress conditions by launching complex programs of gene expression, both transcriptional and posttranscriptional, and which are often closely linked with each other. Read more

Exploiting aberrated DNA damage signalling signatures to identify personalised combination therapies for paediatric cancer treatment

  Research Group: Translational Tumour Biology
More than 140 children with cancer die in Australia each year due to the occurrence of resistance to traditional chemotherapy. To improve overall survival rates for high-risk paediatric cancer patients, treatment developments have been shifted to personalised approaches. Read more

Immune Profiling and Immunotherapy for High-Risk Paediatric Sarcomas

  Research Group: Translational Tumour Biology
Sarcomas are a diverse group of connective tissue tumours that account for ~10% of childhood cancers. However, they are relatively understudied and poorly understood. Read more

Explaining unexplained drug responses in childhood sarcomas

  Research Group: Translational Tumour Biology
Despite aggressive treatments, survival of young, high-risk sarcoma patients is poor and side-effects are frequent. No targeted treatment is available, underlining the unmet need for better and less toxic treatments. Read more

Integrative data analysis: from novel biomarker-drug response associations to predicting effective drug combinations

  Research Group: Translational Tumour Biology
More than 140 children with cancer die in Australia each year due to the occurrence of resistance to traditional chemotherapy. To improve overall survival rates for high-risk paediatric cancer patients, the Children’s Cancer Institute initiated the Zero Childhood Cancer national personalised medicine trial (PRISM). Read more

In vitro immunotherapy testing: towards next level personalised treatment identification

  Research Group: Translational Tumour Biology
Around 200 children are diagnosed with high-risk cancer in Australia each year. Over 140 of these children still die due to the occurrence of resistance to traditional chemotherapy. Read more

Tailored PROTACs to target the undruggable in paediatric cancer

  Research Group: Translational Tumour Biology
Around 200 children are diagnosed with high-risk cancer in Australia each year. Over 140 of these children still die due to the occurrence of resistance to traditional chemotherapy. Read more

Single-cell lineage maps of blood/immune cells in human organoids

Blood/immune cells sustain life through oxygen supply, resistance to infection, and gatekeeping cancer cells. We developed a powerful stem cell culture system that allowed us to recapitulate blood/immune cell development in human organoids. Read more
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