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University of Birmingham Biophysics PhD Projects

We have 4 University of Birmingham Biophysics PhD Projects

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  Multimerisation of ELAV/Hu proteins – a key mechanism ensuring specificity for RNA recognition in health and disease
  Dr M Soller, Dr T Knowles
Applications accepted all year round

Funding Type

PhD Type

Aims. Determine the structure of the ELAV dodecameric complex bound to target RNA by cryoEM and functionally probe interaction interfaces in vitro and in vivo in transgenic Drosophila models for neurodegeneration and cancer.
  Structure and Function Studies on Proteins from Predatory Bacteria
  Dr A Lovering
Applications accepted all year round

Funding Type

PhD Type

Bdellovibrio bacteriovorus is a small predatory bacterium able to invade and kill many different Gram-negative bacterial prey (including human, animal and crop pathogens; e.g.
  Advanced in vitro and in silico models to predict and prevent deep venous thrombosis
  Dr D Vigolo, Dr A Alexiadis
Applications accepted all year round

Funding Type

PhD Type

Deep vein thrombosis (DVT) is a life-threatening and debilitating condition where blood clots form within the deep veins (e.g. the femoral vein in the leg).
  Novel approaches for imaging nucleic acids in the cell
  Dr R K Neely
Applications accepted all year round

Funding Type

PhD Type

Applications are invited for a PhD studentship with the Neely group, School of Chemistry, University of Birmingham. Work in the group focusses on imaging of the DNA molecule and this PhD will build on our work using the DNA methyltransferases to target specific DNA sequences for labelling and analysis.
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