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Biotechnology PhD Research Projects

We have 622 Biotechnology PhD Research Projects

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We have 622 Biotechnology PhD Research Projects

Successfully added to shortlist

EASTBIO Application of statistical methods to quantify telomere length with basepair resolution

  Research Group: Biomedical Sciences Research Centre
BACKGROUND. The sequencing of the human genome in 2001 was a landmark moment in biology. However it has taken 20 years for certain DNA regions such as telomeres to be included in the reference genome, and in most genomic studies they are still excluded. Read more

Design and characterisations of novel antimicrobial biomaterials

Self-assembled nanobiomaterials are becoming an important research theme due to their potential in infection control and wound care, gene and cell delivery, biodevices and tissue regeneration. Read more

EASTBIO COVID-19 Drug Discovery: Discovering Antiviral Compounds that Inhibit SARS-CoV-2 using a Cell-Based Approach.

  Research Group: Biomedical Sciences Research Centre
BACKGROUND. The COVID-19 pandemic is a global health and economic challenge. Despite successful vaccine development and ongoing vaccine rollout, effective treatment options are still urgently required for patients that succumb to serious disease. Read more

EASTBIO: Discovery and evolutionary dynamics of influenza A virus accessory genes

The relatively small coding capacity of RNA viruses means that most, if not all, have evolved a variety of transcriptional and/or translational mechanisms that diversify their coding repertoire such that one gene can produce multiple different polypeptides, often from overlapping open reading frames (ORFs). Read more

EASTBIO Mapping factors and modelling of epigenetic centromere propagation

  Research Group: Institute of Cell Biology
Centromeres are prominent genomic features, readily recognisable as the primary constriction on mitotic chromosomes. They play an essential role in chromosome segregation by connecting chromosomes to the mitotic spindle. Read more

EASTBIO Determining the role of phosphorylation in chronic Toxoplasma gondii cyst formation

  Research Group: Institute of Immunology & Infection Research
Toxoplasma gondii is a highly prevalent parasite, infecting 1/3 of the human population and a wide range of animals. The parasite is a master at subverting host cell processes for its own benefit. Read more

EASTBIO On the origin of environmental RNA interference: multicopy gene families silenced in nematodes

  Research Group: Institute of Evolutionary Biology
RNA molecules can be secreted by cells into their environment, move between cells, and even between different organisms, potentially encoding “messages” that can be understood by the receiver. Read more

EASTBIO Antiviral Defence in Bacillus subtilis

  Research Group: Biomedical Sciences Research Centre
BACKGROUND. All living things, from humans to bacteria, are subject to infection by viruses. For example, one third of the bacteria in the ocean are thought to be infected and killed every day. Read more

EASTBIO Understanding the peat microbiome and metabolome: from vegetation to organic matter molecules and microbes

Peatlands are organic matter rich soils that provide countless benefits and ecological services. They represent the largest terrestrial carbon store, containing twice as much carbon as the entire forest biomass on this planet. Read more

EASTBIO A synthetic biology approach to design intelligent organoids for the study of host-microbe interactions

  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
Organoids are self-organised, 3D structures generated in vitro from adult or pluripotent stem cells, that exhibit similar functionality as their tissue of origin. Read more

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