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Biotechnology PhD Research Projects

We have 442 Biotechnology PhD Research Projects

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I am a non-European student


We have 442 Biotechnology PhD Research Projects

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Understanding the effects of immunomodulatory therapies on radiation response

Radiotherapy can ablate tumours through inducing both DNA damage and anti-tumour inflammatory responses. However, innate immunity pathways mounting inflammatory responses can also afford cell intrinsic radioresistance. Read more

The crosstalk between tumour microenvironments and MAFF to determine transcriptional activation or repression

Radiation is effective in treating many types of cancers by inducing oxidative stress through the generation of reactive oxygen species (ROS) that result in DNA damage, in particular, DNA double strand breaks (DSBs). Read more

RNA-therapeutic approaches for metabolic pathologies

  Research Group: Metabolism & Gene Regulation
Analysis of the proteome and transcriptome has demonstrated the existence of a far greater transcriptomic complexity than previously catalogued. Read more

Targeting polymerase theta as a way to improve radiotherapy and immunotherapy.

Despite technical improvements in radiation delivery, survival rates following radical radiotherapy remain poor for many tumour types and the radiation delivered to adjacent tissues is still frequently associated with significant side-effects. Read more

Ubiquitin signalling in the pathogenesis and radiotherapy of glioblastoma

Glioblastoma accounts for more than 4000 deaths every year in the UK. The cornerstone of glioblastoma treatment is constituted by maximal surgical resection, radiotherapy and chemotherapy. Read more

EASTBIO Investigating the Assembly of Bacterial Encapsulins for the Efficient Engineering of Nanoscale Bioreactors

Encapsulins are bacterial capsid-like nanocompartments roughly 25-30 nm in diameter. These large protein assemblies are made up of either 60 or 180 copies of a single 30 kDa protomers which assemble to form a hollow icosahedral protein cage. Read more

Physical health status and its impact on surgery outcomes - Risk assessment in peri-operative care using a machine learning approach

The quality of life for patients with serious and life-threatening conditions can be transformed with surgery. However, surgery itself is associated with a significant risk of morbidity and mortality because surgical procedures place high stress onto organ systems. Read more

Investigating the genetics of progressive pulmonary fibrosis in multi-ancestry populations

Idiopathic pulmonary fibrosis (IPF) is a chronic disease where the lungs become increasingly scarred. This leads to a reduced quality of life and is eventually fatal however not all individuals experience the same form of the disease. Read more

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