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Molecular Biology PhD Projects in Birmingham

We have 56 Molecular Biology PhD Projects in Birmingham

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  Protein Disulfide Isomerase Inhibition: A Novel Therapeutic Strategy against Pancreatic Cancer
  Dr P Foster, Dr D Tennant
Application Deadline: 6 May 2019
Patients with pancreatic cancer have a very poor prognosis as the disease remains largely incurable. One-year relative survival rate is 20%, with five-year rate just 7%.
  Ensuring chemical safety through toxicity studies in Daphnia using state-of-the-art molecular, imaging and modelling approaches
  Prof M Viant, Dr B Campos, Dr C Rivetti, Dr I Sorrell
Application Deadline: 5 May 2019
This exciting 4-year BBSRC iCASE PhD opportunity bridges the University of Birmingham’s (*) metabolomics team and Unilever’s Safety and Environmental Assurance Centre (SEAC), both having state-of-the-art facilities and renowned research programmes, thereby creating an excellent environment for this challenging yet impactful research project.
  Mybl2 in the regulation of cell fate decisions
  Dr P Garcia
Applications accepted all year round
We are interested in the molecular mechanisms regulating cell fate decisions that occur during normal development, somatic reprogramming and cancer.
  Metabolic control of T cell function
  Dr S Dimeloe
Applications accepted all year round
Current research interests in Sarah Dimeloe’s lab focus on the metabolism and interlinked immune function of T lymphocytes in health and disease.
  Targeting steroid metabolism to block colorectal cancer proliferation
  Dr P Foster, Dr L Cox
Applications accepted all year round
Our group is a world leader in targeting specific aspects of steroid metabolism to block cancer growth. Our research has been instrumental in the successful pre-clinical and clinical development of various novel anti-cancer compounds.
  Repairing DNA Damage in Response to BRAF Mutation
  Dr C McCabe, Prof G Stewart
Applications accepted all year round
We are the leading thyroid cancer research group in the UK; we work on other neoplasias as well, including breast and head and neck etc.
  Targeting the Role of Myeloid Steroid Metabolism in Chronic Inflammation
  Dr R Hardy, Dr P Foster
Applications accepted all year round
Background. Myeloid derived cell populations such as macrophages play a critical role in the early innate immune response, whilst dendritic cells are essential in bridging the progression to an adaptive immune response.
  Polo-like kinase inhibitors for targeted therapy in adrenocortical carcinoma
  Dr C L Ronchi, Dr P Foster
Applications accepted all year round
Adrenocortical carcinoma (ACC) is a rare cancer with a generally poor prognosis and partially unknown pathogenesis.
  Determining the translational potential of the highly phosphorylated proto-oncogene PBF
  Dr V Smith
Applications accepted all year round
In order to translate the many molecular alterations now detectable in human tumours into effective clinical management we need to fully understand their impact on tumour biology.
  Adipose tissue functional responses to nutritional stress
  Dr K Manolopoulos, Prof D Calebiro
Applications accepted all year round
Obesity is the leading cause of insulin resistance and type 2 diabetes. Adipose tissue dysfunction has been proposed as being central in the pathophysiology of obesity-related complications.
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