University of Leeds Cancer Biology PhD Projects, Programmes & Scholarships

Supervisors: Dr S Burke, Dr CB Burnett, Dr KNF Franks

The School of Biomedical Sciences invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

Exploring Synthetic Lethality Interactions through Targeting the SUMO Pathway for Therapeutic Insights

Year round applications PhD Research Project Self-Funded PhD Students Only

The School of Molecular and Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Supervisor: Dr C Bassi

Disrupted SUMO signalling in epithelial cancers, implications for genome stability and response to therapy.

Year round applications PhD Research Project Self-Funded PhD Students Only

The School of Molecular and Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Supervisor: Dr A Garvin

Structural and mechanistic studies of fibroblast growth factor receptor signalling

Supervisors: Prof A.L. Breeze, Prof F. Sobott

The School of Molecular and Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

How does the E5 oncoprotein contribute to human papillomavirus replication and disease?

Supervisors: Dr A Macdonald, Prof A Whitehouse

The School of Molecular and Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

Live cell imaging of epithelial cancer cell proliferation for therapy

Supervisors: Prof A Divan, Dr S Ponnambalam, Dr M A Harrison

The School of Molecular & Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

The role of ubiquitin-modifying enzymes in angiogenesis

Supervisors: Dr S Ponnambalam, Dr M A Harrison

The School of Molecular & Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

Uncovering the links between the environmental sensor, AHR, and the development of breast cancer

Supervisors: Dr C Gorrini, Dr A Zhuravleva

The School of Molecular and Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

NIHR Leeds BRC: The microbiome and the promotion of bowel cancer: The key to understanding causation and prevention of this important disease

Supervisors: Dr K Marks, Dr H Wood, Dr N West, Prof P Quirke

Bowel cancer is the second commonest cause of cancer death in the UK and affects 1.9 million people annually worldwide. Its cause is still unknown but recent work by Wood et al. Read more

26 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

NIHR Leeds BRC: Multimodal predictive modelling of outcome in patients with gastrointestinal cancer

Supervisors: Dr H Grabsch, Dr N West, Dr D Magee

Worldwide, cancer of the upper (oesophagus, stomach) and lower gastrointestinal (colon and rectum) tract is newly diagnosed in 3.6 million patients every year and 2.2 million patients die from this disease every year. Read more

26 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

Epigenetics and Cancer: Determining how Mistakes in V(D)J Recombination Trigger Leukaemias and Lymphomas

Year round applications PhD Research Project Self-Funded PhD Students Only

V(D)J recombination is essential to produce an effective adaptive immune system but since the reaction involves breakage and rejoining of DNA, it is highly dangerous and errors have long been thought to lead to leukaemias and lymphomas. Read more

Supervisor: Dr J Boyes

Cancer: Investigation of accentuated mitochondrial ROS and NLRP3 inflammasome activation in cystic fibrosis and colorectal carcinoma.

Supervisors: Prof D Peckham, Prof D Jayne, Dr S Savic, Miss LR Caley

Cystic fibrosis (CF) is associated with an accentuated inflammatory response to bacterial lipopolysaccharides (LPS), increased resting energy expenditure and a higher than expected prevalence of gastrointestinal and other malignancies. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

Cancer: Characterization of EGFR signaling activated by the endothelium in the process of breast cancer metastasis to the brain

Supervisors: Dr G Mavria, Dr S Bell

The Epidermal Growth Factor Receptor (EGFR) is important in normal physiology regulating epithelial development and homeostasis. In cancer, deregulation resulting from mutation, amplification or transcriptional upregulation promotes tumorigenesis. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

Haematology: Oncogenic reprogramming of immune cells; novel mechanism for drug resistance in leukaemia

Year round applications PhD Research Project Self-Funded PhD Students Only

Under pathogenic challenges, cells of the haematopoietic system become epigenetically reprogrammed and establish immune memory. Read more

Supervisor: Dr P Laslo

Oncology: Evaluating Photodynamic Therapy in colorectal cancer using patient-derived organoids

Supervisors: Dr I Knot, Prof D Jayne

Colorectal cancer (CRC) is the 3rd most common cancer worldwide. Surgery is first line treatment and often in adjunct with chemotherapy. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only