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We have 50 Cardiology PhD Research Projects PhD Projects, Programmes & Scholarships

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Cardiology PhD Research Projects PhD Projects, Programmes & Scholarships

We have 50 Cardiology PhD Research Projects PhD Projects, Programmes & Scholarships

The Role of Reactive Sulfur Species in the Ageing Heart

Second Supervisor. Prof Melanie Madhani, University of Birmingham. Background . Ageing is a natural and complex biological process that involves the gradual deterioration of cells, tissues, and organ systems over time, thus leading to an increased susceptibility to diseases and mortality. Read more

Ageing to Arrhythmias

Cardiac arrhythmias are a leading cause of sudden death and morbidity. This project aims to identify why they occur in the elderly and novel routes to therapies. Read more

Regulation of protein palmitoylation in the heart by persulphidation

Hydrogen sulphide (H2S) is known to have cardioprotective qualities. Persulphidation is a reversible post-translational modification (PTM) in which a persulphide group is formed by the reaction of H2S with the thiol groups of cysteine residues in proteins. Read more

Exploring cardio-renal-metabolic interactions in patients with heart failure

Recent years have highlighted the connections and shared pathophysiology between heart failure, renal impairment, diabetes and obesity, particularly with the evidence of benefit in all of these areas with SGLT2 inhibitors and GLP1-receptor agonists. Read more

Investigation of short-term effects of colchicine on blood proteins using proteomics

The anti-inflammatory medication colchicine has been shown to significantly improve cardiovascular outcomes post heart attack and in chronic heart disease patient groups, suggesting it may be a suitable candidate for repurposing in cardiovascular diseases. Read more

The role of the extracellular matrix in cardiomyocyte developmental (SMITH_U24DTP1)

Primary Supervisor: Dr James Smith . Secondary Supervisor: Dr Iain Macaulay (EI) . Cardiomyocytes are the muscle cells of the heart, responsible for the production of contraction forces. Read more

MScR - Preserving t-tubule function in adult cardiac myocytes in short-term culture

Invaginations of the sarcolemma of adult cardiac myocytes known as transverse (or t-) tubules account for up to 65% of the total sarcolemma surface and play a key role in excitation-contraction (EC) coupling and cell signalling (Hong & Shaw, 2017). Read more

In the game for life: Lifelong welfare, education and support for rugby players

Applications are invited for a fully-funded 3-year PhD to commence in October 2024. . The PhD will be based in the Faculty of Science and Health and the candidate will join the Physical Activity, Health and Rehabilitation Thematic Research Group. Read more

Mechanisms underlying the effects of activated protein C (APC) in cardiac muscle

  Research Group: Chemistry and Biosciences
APC is an anticoagulant enzyme that also exerts antithrombotic, anti-inflammatory, antiapoptotic and a variety of other cytoprotective effects in different tissues, where the mechanism of action is thought to involve the endothelial protein C receptor (EPCR) and a protease activated receptor (PAR). Read more

The effect of early-life stress on cardiac function in later life

Stressful experiences in early childhood can increase the risk of cardiovascular disease (CVD) in later life. How early-life stress (ELS) influences susceptibility to CVD onset remains largely unknown. Read more

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