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Cell Biology / Development PhD Research Projects

We have 423 Cell Biology / Development PhD Research Projects

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We have 423 Cell Biology / Development PhD Research Projects

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CRISPR-based mitophagy screens for regulators of mitochondrial protein import quality control

Mitophagy is a highly selective form of autophagy (cellular self-eating) for the removal of damaged or redundant mitochondria. Failures in its regulation are implicated in numerous human diseases. Read more

Comprehensive analysis of the EBV genome in endemic Burkitt's Lymphoma

Infection-related cancers make up 25% of all cancers world-wide. In particular, Epstein Barr Virus (EBV) causes nasopharyngeal cancer frequently encountered in China and various different types of lymphomas. Read more

Metabolism in inflamed immune microenvironment

CLINICAL OPTION. Immune responses differ drastically depending on where they occur. Tissue microenvironments help control immunity by providing signalling cues, cellular interactions, and importantly, determining the supply of nutrients and metabolites. Read more

EASTBIO: Exploring the potential to manipulate macrophage behaviour in salivary gland regeneration

Radiation injury is characterised by an influx of inflammatory cells. Macrophages have long been considered key cells in the tissue repair process, but they can have both beneficial and detrimental effects on damage resolution and tissue repair, depending on their phenotype and the niche they inhabit. Read more

Metabolism in inflamed immune microenvironments

NON-CLINICAL OPTION. Immune responses differ drastically depending on where they occur. Tissue microenvironments help control immunity by providing signalling cues, cellular interactions, and importantly, determining the supply of nutrients and metabolites. Read more

Exploit the impact of disease-causing HLA variants on cellular phenotypes

The 4 Mb major histocompatibility (MHC) region on chromosome region 6p21.3, which contains the human leukocyte antigen (HLA) complex, plays a vital role in our immune system and is of great importance to many areas of medicine, from organ transplantation and disease diagnosis to cancer immunotherapy. Read more

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