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Endocrinology PhD Research Projects

We have 42 Endocrinology PhD Research Projects

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We have 42 Endocrinology PhD Research Projects

Effect of vitamin D in vascular and endocrine cells

Vitamin D3 deficiency is a common public health problem worldwide that is increasingly believed to contribute not only to decreased bone mineralisation but potentially to other serious medical conditions. Read more

Control of Parathyroid Hormone Secretion

The regulation of parathyroid hormone (PTH) secretion is of fundamental importance for calcium homeostasis and in mineral conditions affecting bone and the kidneys. Read more

Rhythmic control of energy balance - to understand how our internal clocks regulate energy metabolism

24-hour rhythms are present in virtually all aspects of our behaviour and physiology. These rhythms are underpinned by circadian clocks that run throughout the body, and act within each tissue to orchestrate many organ functions and rhythmic activities (e.g. Read more

Lateral hypothalamus as a visual centre controlling arousal, autonomic function and reflex behaviours

In addition to supporting our conscious perception of the world around us, light and visual stimuli exert wide ranging effects on animal physiology and behaviour via hard-wired ‘reflexes’ which range from simple effects of light on sleep, alertness and neuroendocrine function to the avoidance of rapidly approaching objects. Read more

Preferential Gq signalling in diabetes: an electrical switch in incretin action and in diabetes progression?

The progression of type 2 diabetes (T2D) involves development of insulin resistance that is frequently associated with obesity and that is initially compensated by increased insulin secretion from pancreatic β-cells. Read more

Deciphering the role of white and brown adipocytes in metabolic disease

Our work focuses on understanding how obesity drives the development of type 2 diabetes and cardiovascular disease. Specifically, it aims to decipher molecular determinants of adipocyte number and distribution within the body; key factors of susceptibility to obesity-associated cardiometabolic diseases. Read more

Environmental Conditions, Clock and Sleep

Our group investigates circadian clocks in mammals using mice as a model system. We are interested in the question how clocks in different tissues adjust to environmental cues and how the brain integrates this information to produce coherent systemic circadian rhythms. Read more

Investigating the molecular mechanism of effector secretion by the bacterial type IV secretion system

The bacterial type IV secretion system (T4SS) translocates DNA-protein complexes, peptidoglycan and a wide range of effectors proteins into target cells and is responsible for multiple disease conditions in humans. Read more

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