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We have 90 The University of Manchester, Faculty of Biology, Medicine and Health PhD Research Projects PhD Projects, Programmes & Scholarships

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Faculty of Biology, Medicine and Health  The University of Manchester

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The University of Manchester, Faculty of Biology, Medicine and Health PhD Research Projects PhD Projects, Programmes & Scholarships

We have 90 The University of Manchester, Faculty of Biology, Medicine and Health PhD Research Projects PhD Projects, Programmes & Scholarships

Evaluation of MCT1s role in chromatin remodelling and metabolomics changes involved in cancer progression

Monocarboxylate transporter 1 (MCT1) is a transmembrane protein involved in cell metabolism and mediates transport of monocarboxylates (such as pyruvate and lactate) in both directions across plasma membrane. Read more

Sunlight exposure and cutaneous production of vitamin D in Black African/Afro-Caribbean adults

Our main source of vitamin D is through skin exposure to ultraviolet radiation (UVR) in sunlight. Vitamin D is essential for healthy bones and is associated with reduced incidence of several cancers and immune-mediated disorders. Read more

(MB-PhD)Immunomodulation in multiple myeloma

Multiple myeloma is a devastating B-cell malignancy for which there is no cure. The development of immunomodulatory drugs (IMiDs) has proved transformative to multiple myeloma care, however, their remain unanswered questions related to the mechanism of action of this important drug class. Read more

(MB-PhD) MYST Histone Acetyltransferases as Therapeutic Targets in Acute Myeloid Leukaemia

Cytotoxic chemotherapy has been the standard of care for treatment of acute myeloid leukaemia (AML) for the last 50 years. Unfortunately, more often than not, it fails to cure patients, and the 5 years survival rate for all-comers with AML is only around 20%. Read more

(MB-PhD) Gene regulatory networks driving metastatic progression in oesophageal adenocarcinoma

Oesophageal adenocarcinoma (OAC) incidence is increasing and yet survival rates remain very poor. There are limited treatment options, especially for metastatic disease, which is especially problematic as patients usually present with late stage disease. Read more

Grief experiences of patients in a secure mental health inpatient hospital: exploring staff and patient perspectives

Although grief is a part of life, some experiences of grief can lead to a deterioration of mental health. A substantial body of research has been undertaken on grief and grief responses, but few studies have focused on the experiences of those bereaved in secure environments. Read more