We have 92 The University of Manchester, Faculty of Biology, Medicine and Health PhD Research Projects PhD Projects, Programmes & Scholarships

T cell-based immunotherapy has revolutionised the treatment of many different types of cancer. However, to date, these treatments have not been successful or widely used for the treatment of brain tumours. Read more

Supervisors: Dr K Couper, Prof D Brough, Dr OP Pathmanaban

Year round applications PhD Research Project Self-Funded PhD Students Only

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VariantVisualiser: Ensuring precise diagnoses of genetic disorders through the development of intuitive software that facilitates the integration and visualisation of complex informatics with biological and clinical data

The University of Manchester Faculty of Biology, Medicine and Health

Rare diseases affect. This proposal builds on substantial efforts of a Human Genome Organization committee which has proposed a unified professional-standard for representing genomic data which, when finalised, will be adopted world-wide. Read more

Supervisors: Dr S Pettifer, Dr PF Freeman

Year round applications PhD Research Project Self-Funded PhD Students Only

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Targeting the mechanism of small GTPase splice variant RAC1B using ligand design

The University of Manchester Faculty of Biology, Medicine and Health

RAC1 is a small GTPase protein that functions as a key signalling node downstream of various microenvironmental signalling pathways. Read more

Supervisors: Dr RB Bryce, Dr S Butterworth, Dr T Jowitt, Dr A Ucar

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding the evolution of gene regulatory networks through biophysical modelling and machine learning

The University of Manchester Faculty of Biology, Medicine and Health

The ability to coordinate the expression of genes within a cell is at the heart of life. When and how much of a specific gene is turned into a protein is essential for organisms to respond to their environment and to manage resources. Read more

Supervisors: Dr M Lagator, Prof M Rattray

Year round applications PhD Research Project Self-Funded PhD Students Only

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Delineating the IRF6 regulatory network driving periderm formation and function

The University of Manchester Faculty of Biology, Medicine and Health

During development, the ectoderm passes through a series of cell states to produce a self-replenishing, multi-layered epidermis. Initial stratification forms a single-cell layer of flattened periderm cells which act as a barrier to prevent pathological adhesions during embryogenesis. Read more

Supervisors: Prof M Dixon, Dr J Dixon

Year round applications PhD Research Project Self-Funded PhD Students Only

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Eco-evolutionary optimization of synthetic phage therapy

The University of Manchester Faculty of Biology, Medicine and Health

Background. Bacteriophages are viruses that infect bacterial cells, use their cellular machinery to assemble new phage virions, and then kill the cell via lysis to release the virions. Read more

Supervisors: Prof M Brockhurst, Prof P Cai, Dr CI Igler

15 June 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Ocular staining with lissamine green

The University of Manchester Faculty of Biology, Medicine and Health

This project will explore issues related to ocular staining with lissamine green. Read more

Supervisors: Dr P Morgan, Dr C Maldonado-Codina

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating inequalities in the safety of artificial intelligence triage in general practice

The University of Manchester Faculty of Biology, Medicine and Health

Background. GP practices in England provide over 30 million appointments per month. Some are for urgent medical conditions that require urgent treatment where delays in care can lead to patient harm. Read more

Supervisors: Dr B Brown, Dr S Cheraghi-Sohi, Prof E Kontopantelis

26 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Decluttering primary care in England to improve patient safety

The University of Manchester Faculty of Biology, Medicine and Health

Reducing the provision of low-value interventions that expose patients to unnecessary risk of harm, both directly, and indirectly, is key to promoting patient safety and reducing healthcare costs. Read more

Supervisors: Prof E Kontopantelis, Dr M Anderson, Dr RP Parisi, Dr K.H Howells, Prof C Armitage

26 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Eco-evolutionary dynamics of environmental microbiomes

The University of Manchester Faculty of Biology, Medicine and Health

Include details on the project, outlining the objectives, methods and potential outcomes. Include details of training/techniques to be provided. Read more

Supervisors: Prof M Brockhurst, Dr S Nixon, Dr K Coyte

15 June 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Identifying variants impacting splicing of 5’ and 3’ UTRs and underpinning inherited retinal disease

The University of Manchester Faculty of Biology, Medicine and Health

Genomic variation that impacts splicing is well established as a cause of genomic disorders, but is almost exclusively limited to protein-coding exons and introns intersecting protein-coding exons. Read more

Supervisors: Dr J Ellingford, Prof R O'Keefe

15 June 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Assessing the contribution of the human microbiome to paediatric cancer and predisposition and chromosomal instability syndromes

The University of Manchester Faculty of Biology, Medicine and Health

A self-funded PhD studentship is available in the laboratories of Andrew McBain, Stefan Meyer and Chris Knight. The project aims to study the microbiome in paediatric cancer predisposition and chromosomal instability syndromes (CIS). Read more

Supervisors: Prof A McBain, Dr S Meyer, Dr C Knight

Year round applications PhD Research Project Self-Funded PhD Students Only

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Peptide-mediated nanocarrier drug delivery for enhanced brain targeting and treatment of inflammation

The University of Manchester Faculty of Biology, Medicine and Health

This project involves the study of nanoparticles and drug delivery to the brain. The student would be required to make and characterise novel nanoparticles from special lipid molecules of various compositions more suitable for blood-brain barrier (BBB) targeting. Read more

Supervisors: Dr HS Shokr, Dr CT Tapeinos, Dr H Aojula

Year round applications PhD Research Project Self-Funded PhD Students Only

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Optimising the measurement of working memory for assessment of speech-in-noise perception

The University of Manchester Faculty of Biology, Medicine and Health

The ability to hear and understand speech in a noisy background is vitally important to good communication, and ultimately a good quality of life. Read more

Supervisors: Dr A Heinrich, Dr R Millman, Dr S Couth

Year round applications PhD Research Project Self-Funded PhD Students Only

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Collective problem-solving and rationality in early childhood

The University of Manchester Faculty of Biology, Medicine and Health

Reasoning has traditionally been viewed as an individual skill. However, recent accounts emphasize its social dimension (Mercier & Sperber, 2011) suggesting that collectives can make inferences to maximize the outcomes for both the individual and the collective (Tomasello, 2019). Read more

Supervisors: Dr B.K Koymen, Dr B.LP Lopez-Perez, Dr K Jensen, Dr B.K Kandemirci

15 June 2024 PhD Research Project Funded PhD Project (UK Students Only)

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We have 92 The University of Manchester, Faculty of Biology, Medicine and Health PhD Research Projects PhD Projects, Programmes & Scholarships

The University of Manchester, Faculty of Biology, Medicine and Health PhD Research Projects PhD Projects, Programmes & Scholarships

We have 92 The University of Manchester, Faculty of Biology, Medicine and Health PhD Research Projects PhD Projects, Programmes & Scholarships

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