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We have 88 Genetics (self) PhD Research Projects PhD Projects, Programmes & Scholarships

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Genetics (self) PhD Research Projects PhD Projects, Programmes & Scholarships

We have 88 Genetics (self) PhD Research Projects PhD Projects, Programmes & Scholarships

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Understanding the role of spliceosome gene mutations in disease

The University of Manchester Faculty of Biology, Medicine and Health
The DNA of a cell is copied into a pre-messenger RNA (pre-mRNA) that the cell uses as a template for protein production. Some of the information contained in DNA is not required for making proteins, therefore, unwanted information must be removed before a protein is made. Read more
 Supervisors: Prof R O'Keefe, Prof B Newman
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Therapeutic resolution of Myelodysplastic Syndrome (MDS) by natural products

University of Bradford Faculty of Life Sciences
  Research Group: Pharmacology and Experimental Therapeutics
Myelodysplastic syndromes (MDS) are a type of blood cancer where the patients do not have enough healthy blood cells. Read more
 Supervisors: Dr T Nasim, Dr M Najafzadeh
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The role of vitamin D3 in treating skin cancer and preventing drug resistance

University of Bradford Faculty of Life Sciences
  Research Group: Chemistry and Biosciences
During the last decade numerous studies have alluded to vitamin D. 3. playing a role in the prevention of cancer. Recent clinical trials looking at the potential role of vitamin D. Read more
 Supervisors: Dr M Sutherland, Dr H Sheldrake, Dr S Kauser
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Exploring the role of interferon stimulated genes (ISGs) in stem cells of serous ovarian cancer

University of Bradford Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Epithelial ovarian cancer (EOC) is the leading cause of mortality in women due to gynaecological cancers. High-grade serous ovarian cancer (HGSOC) accounts for 70-80% of patients with EOC. Read more
 Supervisors: Dr S Swaroop, Dr G Grimaldi, Dr ED Perkins
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the cellular functions of Trappc9 in brain development and microcephaly

University of Liverpool Institute of Systems, Molecular and Integrative Biology
This PhD project will investigate the cellular functions of the Trafficking protein particle complex subunit 9 (Trappc9) and its roles in brain development. Read more
 Supervisors: Dr A Plagge, Dr T Zech
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Join Our Quest to Unravel the Secrets of Eukaryotic Genomes!

University of Leicester Molecular and Cell Biology
We're on the lookout for passionate PhD students who are eager to delve deep into the mysteries of our DNA. Our quest? To understand the subtle changes that determine how our genes function, both in sickness and in health. Read more
 Supervisor: Dr T Schalch
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Short and long-distance communication in cancer: Feedback regulation of Ras signalling in tumourigenesis and cachexia

Cardiff University Cardiff School of Biosciences
Hamaratoglu Lab studies cell-cell signalling in development and tumourigenesis. We take advantage of outstanding genetic tools in Drosophila, and use larval imaginal discs as model epithelial organs. Read more
 Supervisors: Dr F Hamaratoglu, Dr C Hogan
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Engineering more water-use efficient crops: functional genomics of CO2 fixation during Crassulacean acid metabolism

University of Liverpool Institute of Systems, Molecular and Integrative Biology
The world is getting hotter and drier due to climate change, and the human population is growing rapidly. Furthermore, it has been predicted that we will need to increase crop yields by 50 - 70 % by 2050 in order to feed the predicted 9 - 10 billion people. Read more
 Supervisors: Dr J Hartwell, Dr P Walley
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Genotypic and phenotypic markers of resistance in Aspergillus fumigatus and their impact on outcomes in chronic pulmonary aspergillosis

The University of Manchester Faculty of Biology, Medicine and Health
Chronic pulmonary aspergillosis (CPA) is a progressive infection affecting patients with chronic lung disease. It significantly affects quality of life and mortality. Read more
 Supervisors: Dr CK Kosmidis, Dr M Bromley, Dr R Richardson, Dr M Bottery, Prof T Hussell
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Genetics: Investigating the functional effect of novel genes and genetic variants in malignant hyperthermia susceptibility using model systems

University of Leeds Faculty of Medicine and Health
Malignant hyperthermia (MH) is an inherited condition, where patients exposed to anaesthetic drugs are susceptible to a dramatic hyperthermic and hypermetabolic response that can contribute to a significant proportion of post-operative morbidity and deaths. Read more
 Supervisors: Prof P Hopkins, Dr M-A Shaw, Dr C Diggle
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cancer: Investigation of accentuated mitochondrial ROS and NLRP3 inflammasome activation in cystic fibrosis and colorectal carcinoma.

University of Leeds Faculty of Medicine and Health
Cystic fibrosis (CF) is associated with an accentuated inflammatory response to bacterial lipopolysaccharides (LPS), increased resting energy expenditure and a higher than expected prevalence of gastrointestinal and other malignancies. Read more
 Supervisors: Prof D Peckham, Prof D Jayne, Dr S Savic, Miss LR Caley
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cancer: Characterization of EGFR signaling activated by the endothelium in the process of breast cancer metastasis to the brain

University of Leeds Faculty of Medicine and Health
The Epidermal Growth Factor Receptor (EGFR) is important in normal physiology regulating epithelial development and homeostasis. In cancer, deregulation resulting from mutation, amplification or transcriptional upregulation promotes tumorigenesis. Read more
 Supervisors: Dr G Mavria, Dr S Bell
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the mechanisms of antibacterial action of silver and copper ions and nanoparticles, and the emerging threat of metal-ion resistance

University of Reading Department of Biomedical Sciences
Project Overview. The emergence of bacterial strains with resistance to multiple classes of antibiotics has led to renewed interest in the antimicrobial properties of metals including silver. Read more
 Supervisor: Dr G Mulley
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Developing a forensic DNA legislative framework and policy for Africa (Ref: SF22/HLS/APP/AMANKWAA)

Northumbria University Faculty of Health and Life Sciences
The use of forensic DNA and national DNA databases (NDNAD) has gained popularity in criminal investigations globally [1]. While the technology has been embraced in Europe and other high-income countries, its use and regulation are still at an infant stage in Africa [2]. Read more
 Supervisor: Dr A Amankwaa
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating mechanical mechanisms underlying osteoarthritis

Cardiff University Cardiff School of Biosciences
Project Description. Osteoarthritis is the major global cause of pain and disability affecting nearly 30million people in the US and 10 million in the UK. Read more
 Supervisors: Dr D Mason, Dr SJG Gilbert
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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