Norwich Research Park Featured PhD Programmes
University of Oxford Featured PhD Programmes
Norwich Research Park Featured PhD Programmes

Genetics PhD Research Projects

We have 451 Genetics PhD Research Projects

Discipline

Discipline

Biological & Medical Sciences

Location

Location

All locations

Institution

Institution

All Institutions

PhD Type

PhD Type

PhD Research Projects

Funding

Funding

I am a non-European student


We have 451 Genetics PhD Research Projects

PhD saved successfully

Building a pyrenoid-based CO2-concentrating mechanism in higher plants

  Research Group: Institute of Molecular Plant Sciences
Photosynthesis is one of the key engineering targets for synthetic biologists to enhance the yield potential of globally important crops. Read more

How to build chromosome segregation machinery in meiosis and mitosis

  Research Group: Institute of Cell Biology
Genes must be passed on accurately from cell to cell and from parents to children.  Failure to do so can be a cause or contributing factor in human illnesses, such as cancer or reproductive/birth defects. Read more

Antiviral RNA-binding proteins

Most clinically important viruses have a genome composed of RNA or generate RNA intermediates during their replication. For this reason, the host cell has developed specialised RNA-binding proteins that detect the presence of the viral RNAs. Read more

New methods for detecting and quantifying genetic adaptation

  Research Group: Institute of Evolutionary Biology
Understanding how populations adapt to their environment is a major focus of evolution research. Falling sequencing costs means genome data is more abundant than ever, but we still lack efficient methods for using it to infer and quantify the effects of natural selection. Read more

Machine learning vs mechanistic models: how best to untangle biological principles?

  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
Our appetite for ever more detailed and complex data has made computation indispensable to biological research. Over the past decades, computational systems models that capture the mechanistic interplay between biological components, have brought major advances to ourunderstanding of the inner working of living cells. Read more

Post-translational regulation of stress-responsive transcription dynamics in plants

  Research Group: Institute of Molecular Plant Sciences
Precise regulation of gene expression is vital for all organisms. In eukaryotes, dynamic changes in gene expression orchestrate cell development and cellular responses to the ever changing environment. Read more

Analysing cancer networks evolution using graph neural networks

  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
Background. The classical model of cancer formation suggests that tumors arise from the stochastic accumulation of somatic mutations in key genes, called cancer driver genes, which equip an aberrant cell with the ability to escape apoptosis, elude the immune system and grow uncontrollably throughout the body [1]. Read more

Synthetic-evolution: linking genomics to biophysics to understand the rules of life.

  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
The genome of every organism encodes genes and regulatory elements required for building and maintaining cells in homeostasis. However, it is still unknown what is the minimal set of genomic elements necessary and sufficient for cellular life. Read more

Seeing double: how do dsRNA binding pseudoenzymes regulate vertebrate mRNAs?

  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
Pre-mRNAs and mRNAs are regulated post-transcriptionally by a variety of different mechanisms that include splicing and editing, which alter the information content of the RNAs. Read more

Understanding the genetic basis of cancer and associated comorbidities using heritability analysis

  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
Decades of research have shown that inherited mutations in key genes can trigger tumorigenesis. However, this evidence has been limited to low-frequency highly penetrant mutations, typically found in patients affected by cancer syndromes, which represent only a small fraction of all malignancies. Read more

Epigenetic mechanisms in genome regulation

  Research Group: Institute of Cell Biology
Epigenetic ‘signals’ such as post-translational histone modifications and RNAi-related small RNAs play key roles in eukaryotic genome regulation, and dysregulation of these signals is associated with a number of diseases including cancers. Read more

Investigating the systems physiology of obesity using Drosophila

  Research Group: Institute of Cell Biology
Obesity levels are rising rapidly around the world and are a major risk factor for diseases such as Type 2 diabetes, cancers and recently, COVID-19. Read more

Filtering Results